Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mickaël Bettan"'
Publikováno v:
Experimental Hematology. 29:295-300
Objective A new intramuscular DNA electrotransfer method for erythropoietin (EPO) expression was evaluated in the natural mouse model of human β-thalassemia (Hbb-thal1) in terms of its ability to reverse the anemia and improve the thalassemic featur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5546ea5da45850af335bd2e5b4eb5b2e
https://doi.org/10.1016/s0301-472x(00)00679-2
https://doi.org/10.1016/s0301-472x(00)00679-2
Autor:
I. Kuzniak, Julien Zuber, A. Houque, Daniel Scherman, Yves Beuzard, E. Tomkiewitcz, A. Henri, Mickaël Bettan, Emmanuel Payen
Publikováno v:
The Journal of Gene Medicine. 3:498-504
Background The combination of physiologically and pharmacologically controlled elements may provide a means to ensure both the regulation and the safety of transgene expression – two major goals in gene therapy. Methods A two-gene modulation system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3202deb116987d025bdccae398ae4924
https://doi.org/10.1002/jgm.217
https://doi.org/10.1002/jgm.217
Autor:
Florence Emmanuel, Abderrahim Mahfoudi, Daniel Scherman, Pia Delaère, Mickaël Bettan, Didier Branelec, Fabienne Soubrier, Jean-Michel Caillaud, Nicolas Duverger, Raphaël Darteil
Publikováno v:
Molecular Therapy. 2:204-210
Numerous diseases are linked to the absence or insufficient concentration of a specific plasma protein. Gene transfer is an appealing strategy for correction of such diseases. We report high and sustained plasma secretion of human secreted alkaline p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adf07b4d4a868c0cd68e15e66826e09
https://doi.org/10.1006/mthe.2000.0117
https://doi.org/10.1006/mthe.2000.0117
Autor:
Daniel Scherman, Mickaël Bettan, Lluis M. Mir, Florence Boissière, Marie-Agnès Ivanov, Pia Delaère
Publikováno v:
Bioelectrochemistry. 52:83-90
DNA transfer to tumor cells of antiproliferative genes or of genes coding for immunomodulatory or antiangiogenic products is a promising approach for cancer therapy. However, intratumoral injection of plasmid DNA either naked or associated to chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d79678089dae4bac88ff8559f1cf624
https://doi.org/10.1016/s0302-4598(00)00087-8
https://doi.org/10.1016/s0302-4598(00)00087-8
Publikováno v:
The Journal of Gene Medicine. 1:245-250
Background Direct intramuscular plasmid DNA injection has recently been proposed for erythropoietin therapy, as an alternative to either systemic injection of recombinant erythropoietin or the use of viral vectors for erythropoietin gene transfer. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9abc004e04b88a1f37c7609bcb7cdcf
https://doi.org/10.1002/(sici)1521-2254(199907/08)1:4<245::aid-jgm49>3.0.co
https://doi.org/10.1002/(sici)1521-2254(199907/08)1:4<245::aid-jgm49>3.0.co
Publikováno v:
Analytical Biochemistry. 271:187-189
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b254a6574489e7c137fe266e7abf4e
https://doi.org/10.1006/abio.1999.4144
https://doi.org/10.1006/abio.1999.4144
Publikováno v:
Neuromuscular disorders : NMD. 13(2)
Duchenne muscular dystrophy is an X-linked genetic disease caused by the absence of functional dystrophin. Pharmacological upregulation of utrophin, the autosomal homologue of dystrophin, offers a potential therapeutic approach to treat Duchenne pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987206ac3c29e97d2ed12d6b762d76df
https://pubmed.ncbi.nlm.nih.gov/12565912
https://pubmed.ncbi.nlm.nih.gov/12565912
Publikováno v:
Arthritis Research. 3:P42
Gene delivery to skeletal muscle and to tumors is a promising strategy for the treatment of muscle disorders or cancer, and for the systemic secretion by muscle of therapeutic proteins. We and others have reported efficient plasmid DNA transfer into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe29cfbd0cc9700e09bb7a3619adf83c
https://doi.org/10.1186/ar370
https://doi.org/10.1186/ar370