Zobrazeno 1 - 10 of 92 pro vyhledávání: '"Mick M Welling"'
1
Akademický článek
In vivo detection of amyloid-β deposits using heavy chain antibody fragments in a transgenic mouse model for Alzheimer's disease.
Autor: Rob J A Nabuurs, Kim S Rutgers, Mick M Welling, Athanasios Metaxas, Maaike E de Backer, Maarten Rotman, Brian J Bacskai, Mark A van Buchem, Silvère M van der Maarel, Louise van der Weerd
Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38284 (2012)
This study investigated the in vivo properties of two heavy chain antibody fragments (V(H)H), ni3A and pa2H, to differentially detect vascular or parenchymal amyloid-β deposits characteristic for Alzheimer's disease and cerebral amyloid angiopathy.
Externí odkaz: https://doaj.org/article/345936b88cb54209aa94fbd068f64428
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2
Akademický článek
Evaluation of [68Ga]Ga-DOTA-AeK as a Potential Imaging Tool for PET Imaging of Cell Wall Synthesis in Bacterial Infections
Autor: Palesa C. Koatale, Mick M. Welling, Sipho Mdanda, Amanda Mdlophane, John Takyi-Williams, Chrisna Durandt, Iman van den Bout, Frederik Cleeren, Mike M. Sathekge, Thomas Ebenhan
Publikováno v: Pharmaceuticals, Vol 17, Iss 9, p 1150 (2024)
The ability of bacteria to recycle exogenous amino acid-based peptides and amino sugars for peptidoglycan biosynthesis was extensively investigated using optical imaging. In particular, fluorescent AeK–NBD was effectively utilized to study the pept
Externí odkaz: https://doaj.org/article/062210055b9a4ad49919985adba3223a
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3
Akademický článek
Combinatory Use of hLF(1-11), a Synthetic Peptide Derived from Human Lactoferrin, and Fluconazole/Amphotericin B against Malassezia furfur Reveals a Synergistic/Additive Antifungal Effect
Autor: Carlo P. J. M. Brouwer, Bart Theelen, Youp van der Linden, Nick Sarink, Mahfuzur Rahman, Saleh Alwasel, Claudia Cafarchia, Mick M. Welling, Teun Boekhout
Publikováno v: Antibiotics, Vol 13, Iss 8, p 790 (2024)
Objective: The increasing resistance of Malassezia yeasts against commonly used antifungal drugs dictates the need for novel antifungal compounds. Human lactoferrin-based peptides show a broad spectrum of antimicrobial activities. Various assays were
Externí odkaz: https://doaj.org/article/61a09555041d480a8dd918812150d5f0
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4
Akademický článek
A radio- and fluorescently labelled tracer for imaging and quantification of bacterial infection on orthopaedic prostheses a proof of principle study
Autor: Mick M. Welling, Kim Warbroek, Chrow Khurshid, Matthias N. van Oosterom, Daphne D. D. Rietbergen, Mark G. J. de Boer, Rob G. H. H. Nelissen, Fijs W. B. van Leeuwen, Bart G. Pijls, Tessa Buckle
Publikováno v: Bone & Joint Research, Vol 12, Iss 1, Pp 72-79 (2023)
AimsArthroplasty surgery of the knee and hip is performed in two to three million patients annually. Periprosthetic joint infections occur in 4% of these patients. Debridement, antibiotics, and implant retention (DAIR) surgery aimed at cleaning the i
Externí odkaz: https://doaj.org/article/e84d6ce3e47e4fad9b93502a3bbeaf06
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5
Akademický článek
Feasibility of fluorescence imaging at microdosing using a hybrid PSMA tracer during robot-assisted radical prostatectomy in a large animal model
Autor: Paolo Dell’Oglio, Danny M. van Willigen, Matthias N. van Oosterom, Kevin Bauwens, Fabian Hensbergen, Mick M. Welling, Huijbert van der Stadt, Elise Bekers, Martin Pool, Pim van Leeuwen, Tobias Maurer, Fijs W. B. van Leeuwen, Tessa Buckle
Publikováno v: EJNMMI Research, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Background With the rise of prostate-specific membrane antigen (PSMA) radioguided surgery, which is performed using a microdosing regime, demand for visual target confirmation via fluorescence guidance is growing. While proven very effective
Externí odkaz: https://doaj.org/article/7f23ca2d80ae44559c65dc4d0cb5c20e
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6
Advancing intraoperative magnetic tracing using 3D freehand magnetic particle imaging
Autor: Lennert Molenaar, Lejla Alic, Mick M. Welling, Melissa Mathilde van de Loosdrecht, Samaneh Azargoshasb, Danny M. van Willigen, Tessa Buckle, Fijs W. B. van Leeuwen, Alexander Winter, Matthias N. van Oosterom, Giuseppe Rosiello
Publikováno v: International Journal of Computer Assisted Radiology and Surgery
International journal of computer assisted radiology and surgery, 17(1), 211-218. Springer
International Journal of Computer Assisted Radiology and Surgery, 17(1), 211-218. SPRINGER HEIDELBERG
Purpose Sentinel lymph node biopsy is a routine procedure for nodal staging in penile cancer. Most commonly, this procedure is guided by radioactive tracers, providing various forms of preoperative and intraoperative guidance. This is further extende
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de984c5d69ef094429b2883441c965e
http://europepmc.org/articles/PMC8738628
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7
Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen: Tuning Pharmacokinetic Properties and Exploring Dye-Protein Interaction
Autor: Margret Schottelius, Henk G. van der Poel, Gabri van der Pluijm, Mick M. Welling, Albertus W. Hensbergen, Wytske M. van Weerden, Hans-Jürgen Wester, Fijs W. B. van Leeuwen, Felicia A. van der Wijk, Danny M. van Willigen, Tobias Maurer, Tessa Buckle
Publikováno v: Journal of Nuclear Medicine, 61(2), 234-241. Society of Nuclear Medicine and Molecular Imaging
Journal of Nuclear Medicine, 61(2), 234-241. SOC NUCLEAR MEDICINE INC
Prostate cancer surgery is currently being revolutionized by the use of prostate-specific membrane antigen (PSMA)-targeted radiotracers, for example, (99)mTc-labeled PSMA tracer analogs for radioguided surgery. The purpose of this study was to develo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8667a811e6c40e56d96ca47b09e5fa42
https://doi.org/10.2967/jnumed.119.233064
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9
Microspheres as a Carrier System for Therapeutic Embolization Procedures: Achievements and Advances
Autor: Mick. M. Welling, Nikolas Duszenko, Maarten P. van Meerbeek, Tom J. M. Molenaar, Tessa Buckle, Fijs W. B. van Leeuwen, Daphne D. D. Rietbergen
Publikováno v: Journal of Clinical Medicine. 12:918
The targeted delivery of anti-cancer drugs and isotopes is one of the most pursued goals in anti-cancer therapy. One of the prime examples of such an application is the intra-arterial injection of microspheres containing cytostatic drugs or radioisot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fdb237d14b01bda85a751361f283643e
https://doi.org/10.3390/jcm12030918
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10
In vivo stability of supramolecular host–guest complexes monitored by dual-isotope multiplexing in a pre-targeting model of experimental liver radioembolization
Autor: Tessa Buckle, Mick M. Welling, Meta Roestenberg, Silvia J. Spa, Fijs W. B. van Leeuwen, Danny M. van Willigen, D.D.D. Rietbergen
Publikováno v: Journal of Controlled Release, 293, 126-134
Journal of Controlled Release 293 (2019)
Introduction: Cyclodextrin (CD)-based supramolecular interactions have been proposed as nanocarriers for drug delivery. We previously explored the use of these supramolecular interactions to perform targeted hepatic radioembolization. In a two-step p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a78f5dff940db949f2ac268d1cfe84
https://doi.org/10.1016/j.jconrel.2018.11.020
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