Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mick Brown"'
Autor:
Rachel Eyre, Denis G. Alférez, Angélica Santiago-Gómez, Kath Spence, James C. McConnell, Claire Hart, Bruno M. Simões, Diane Lefley, Claudia Tulotta, Joanna Storer, Austin Gurney, Noel Clarke, Mick Brown, Sacha J. Howell, Andrew H. Sims, Gillian Farnie, Penelope D. Ottewell, Robert B. Clarke
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
In breast cancer, dormant cancer cells may develop into bone metastases. Here, the authors demonstrate that microenvironmental IL1β stimulates metastatic breast cancer cell colonisation in the bone via IL1β-NFKB/CREB-Wnt pathway activation and canc
Externí odkaz:
https://doaj.org/article/c9b7748a363e46eb80d945fea7c4be66
Following the recognition that airborne particulate matter, even at quite modest concentrations, has an adverse effect on human health, there has been an intense research effort to understand the mechanisms and quantify the effects. One feature that
Autor:
Ashwin Sachdeva, Claire A. Hart, Kyungmin Kim, Thomas Tawadros, Pedro Oliveira, Jonathan Shanks, Mick Brown, Noel Clarke
Publikováno v:
Sachdeva, A, Hart, C A, Kim, K, Tawadros, T, Oliveira, P, Shanks, J, Brown, M & Clarke, N 2022, ' Non-canonical EphA2 activation underpins PTEN-mediated metastatic migration and poor clinical outcome in prostate cancer ', British Journal of Cancer . https://doi.org/10.1038/s41416-022-01914-3
Background The key process of mesenchymal to amoeboid transition (MAT), which enables prostate cancer (PCa) transendothelial migration and subsequent development of metastases in red bone marrow stroma, is driven by phosphorylation of EphA2S897 by pA
Autor:
Mick Brown
In 1897, an Indian yogi named Bava Lachman Dass exhibited himself at the Westminster Aquarium in London, demonstrating forty-eight yoga positions to a bemused audience. Four years earlier, Hindu philosopher Swami Vivekananda had spoken at the first W
Publikováno v:
Architectural Science Review. 52:261-269
Biodiversity is one aspect of a natural environment affected by the construction of buildings and the manufacture of building materials. However, the complexity of biodiversity impact assessment and the lack of a meaningful surrogate or indicator for
Publikováno v:
Physics Education. 38:398-405
This article is the second of a pair of articles about randomness in physics. In the preceding article we have shown how simple random walk arguments can give the mean and standard deviation of a number of random counts. In this article we go a littl
Publikováno v:
Physics Education. 38:391-397
This is the first of a pair of articles about randomness in physics. In this article, we use some variations on the idea of a `random walk' to consider first the path of a particle in Brownian motion, and then the random variation to be expected in r
Autor:
Mick Brown
In 2002, the reclusive and legendary record producer Phil Spector gave his first interview in twenty-five years to Mick Brown. The day after it was published an actress named Lana Clarkson was shot dead in Spector's LA castle. This is Brown's odyssey
Publikováno v:
Europe PubMed Central
The considerable morbidity and mortality associated with certain human papillomaviruses (HPV) has provided the impetus for HPV vaccine development. The design of such vaccines has evolved from an understanding of the nature of HPV infections and thei
Publikováno v:
Physics World. 10:45-50
No Chain is stronger than its weakest link. That may be a cliche, but it is certainly true of materials such as ceramics and metals. They nearly always consist of crystallites of varying orientation, and the boundaries between one grain and another a