Zobrazeno 1 - 10
of 319
pro vyhledávání: '"Michniak, P."'
Publikováno v:
AAPS Open, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract This research study involves the development of an olanzapine (OLZ) formulation using various chemical penetration enhancers (CPEs) for transdermal delivery. The aim of this study was to obtain the initial data needed about the effects of va
Externí odkaz:
https://doaj.org/article/ce333515012140af83ffe10fc3f32756
Autor:
Anna Gościniak, Anna Stasiłowicz-Krzemień, Bożena Michniak-Kohn, Piotr Fiedor, Judyta Cielecka-Piontek
Publikováno v:
Molecules, Vol 29, Iss 12, p 2938 (2024)
Chronic wound treatments pose a challenge for healthcare worldwide, particularly for the people in developed countries. Chronic wounds significantly impair quality of life, especially among the elderly. Current research is devoted to novel approaches
Externí odkaz:
https://doaj.org/article/9d78ccc12bf84755b7a9cb7e08e68cca
Publikováno v:
Scientia Pharmaceutica, Vol 92, Iss 2, p 29 (2024)
Thymoquinone (TQ), a bioactive compound found in Nigella sativa seeds, possesses diverse therapeutic properties for skin conditions. However, formulating TQ presents challenges due to its hydrophobic nature and chemical instability, which hinder its
Externí odkaz:
https://doaj.org/article/f88bb61469964a69a78bf178306c34c5
Autor:
Khea Wolff, Keyaara Robinson, Nanjoo Suh, Bozena Michniak-Kohn, Michael Goedken, Marianne Polunas, Ilya Raskin
Publikováno v:
Phytomedicine Plus, Vol 3, Iss 4, Pp 100479- (2023)
Background: Moringa (Moringa oleifera Lam.) seed extract (MSE) and its primary bioactive compound, moringa isothiocyanate-1(MIC-1), mitigate inflammation, oxidative stress, diabetes, and cancer in the in vivo rodent models following oral application.
Externí odkaz:
https://doaj.org/article/8d877aa15c8a4824aa5e37df1dfbb8af
Autor:
Joachim Kohn, Bozena Michniak-Kohn
Publikováno v:
Journal of Medical Science, Vol 92, Iss 3 (2023)
Much of the priorities in drug delivery research are focused on targeted drug delivery for cancer therapies and a wide range of controlled drug release systems for commonly used active pharmaceutical ingredients (APIs). In this “thousand words arti
Externí odkaz:
https://doaj.org/article/fc3d7a7320354232aa039986a24b30f6
Autor:
Bozena Michniak-Kohn, Joachim Kohn
Publikováno v:
Journal of Medical Science, Vol 92, Iss 3 (2023)
Background. The skin’s uppermost layer, the stratum corneum is a very effective barrier against the penetration of compounds including pharmaceuticals and cosmetic actives. To deliver higher amounts of drugs into the skin layers or to deliver drugs
Externí odkaz:
https://doaj.org/article/3a5cc65c33174dc7a2308fe22b8f286a
Akademický článek
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Autor:
Katarzyna Witkowska, Magdalena Paczkowska-Walendowska, Tomasz Plech, Daria Szymanowska, Bożena Michniak-Kohn, Judyta Cielecka-Piontek
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17229 (2023)
Centella asiatica extract is a valued plant material with known anti-inflammatory and anti-microbiological properties. Using the Design of Experiment (DoE) approach, it was possible to obtain an optimized water/alcoholic extract from Centella asiatic
Externí odkaz:
https://doaj.org/article/ed489727dab2401fb325296aa01ca9f9
Autor:
Namrata S. Matharoo, Harsha T. Garimella, Carrie German, Andrzej J. Przekwas, Bozena Michniak-Kohn
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15118 (2023)
The administration of therapeutic drugs through dermal routes, such as creams and ointments, has emerged as an increasingly popular alternative to traditional delivery methods, such as tablets and injections. In the context of drug development, it is
Externí odkaz:
https://doaj.org/article/988b0933aba4449390ed5fb037aa6fbb
Autor:
Magdalena Paczkowska-Walendowska, Andrzej Miklaszewski, Bożena Michniak-Kohn, Judyta Cielecka-Piontek
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1777 (2023)
Despite the wide pharmacological action of polyphenols, their usefulness is limited due to their low oral bioavailability, which is due to their low solubility and rapid first-pass metabolism. Red vine leaf extract is an herbal medicine containing se
Externí odkaz:
https://doaj.org/article/5d3ef1d9b19a42b48336ceef9d815c77