Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Michizane Hashimoto"'
Autor:
Takayoshi Kinoshita, Hideyuki Muramatsu, Motoo Kobayashi, Michizane Hashimoto, Seiji Yoshimura, Yoko Deai, Hidenori Ohki, Kazuki Okada, Satoshi Sasamura, Yukiko Yamagishi
Publikováno v:
The Journal of Antibiotics. 68:511-520
FR901459, a product of the fungus Stachybotrys chartarum No. 19392, is a derivative of cyclosporin A (CsA) and a powerful immunosuppressant that binds cyclophilin. Recently, it was reported that CsA was effective against hepatitis C virus (HCV). Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bc32e5ecb487bcf0c1e2fd4ab64393
https://doi.org/10.1038/ja.2015.19
https://doi.org/10.1038/ja.2015.19
Autor:
Shigehiro Takase, Masami Ezaki, Koji Yoshikawa, Michizane Hashimoto, Hirohito Kai, Kumiko Nitta, Akihiko Fujie, Ikuko Nakamura, Hideyuki Muramatsu, Masato Watanabe, Midori Yamashita, Noriaki Inamura
Publikováno v:
The Journal of Antibiotics. 66:465-471
The novel antifungal macrocyclic lipopeptidolactone, KB425796-A (1), was isolated from the fermentation broth of bacterial strain 530603, which was identified as a new Paenibacillus species based on morphological and physiological characteristics, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f69486f7c9fd771862ac5a84e21c705
https://doi.org/10.1038/ja.2013.63
https://doi.org/10.1038/ja.2013.63
Publikováno v:
Bioscience, biotechnology, and biochemistry. 56(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09207a38de05e86e7f2d03b0ccdc353b
https://pubmed.ncbi.nlm.nih.gov/27286227
https://pubmed.ncbi.nlm.nih.gov/27286227
Autor:
Akihiko Fujie, Shigetada Furukawa, Teruhisa Masaki, Keisuke Ohsumi, Ikuko Nakamura, Michizane Hashimoto, Seiji Yoshimura, Shigehiro Takase
Publikováno v:
The Journal of antibiotics. 70(1)
The novel antifungal agent ASP2397 (Vical's compound ID VL-2397) is produced by the fungal strain MF-347833 that was isolated from Malaysian leaf litter and is identified here as an Acremonium species based on its morphology, physiological properties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a893779ce93338c8f1c0ac51ea4c00e
https://pubmed.ncbi.nlm.nih.gov/27599768
https://pubmed.ncbi.nlm.nih.gov/27599768
Autor:
Shigehiro Takase, Satoshi Sasamura, Michizane Hashimoto, Motohiro Hino, Takashi Fujii, Hideyuki Muramatsu, Akihiko Fujie, Kazutoshi Sakamoto
Publikováno v:
The Journal of Antibiotics. 63:637-642
AS1387392 was a novel and powerful histone deacetylase inhibitor with an excellent oral absorption profile, but this compound was lacking in active moieties, which are essential to synthesize more derivatives. In our screening program to identify act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37adda7c316fe6c6d53c8fd978517761
https://doi.org/10.1038/ja.2010.89
https://doi.org/10.1038/ja.2010.89
Autor:
Ryuichi Kanasaki, Michizane Hashimoto, Motohiro Hino, Yasuhiro Hori, Yasuhisa Tsurumi, Akihiko Fujie, Shigehiro Takase, Seiji Hashimoto, Kazutoshi Sakamoto
Publikováno v:
The Journal of Antibiotics. 59:137-144
Novel antifungal lipopeptides, FR209602, FR209603 and FR209604, were isolated from the fermentation broth of a fungal strain No. 738 which was identified as Coleophoma crateriformis from morphological and physiological characteristics. The antibiotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2780f5560d56f0f4e35336bd5df9d2
https://doi.org/10.1038/ja.2006.20
https://doi.org/10.1038/ja.2006.20
Publikováno v:
Journal of Bioscience and Bioengineering. 100:567-572
Cytochrome P450 enzymes are a major class of biocatalysts related to the oxidative metabolism of many drugs, assisted by electron transfer partners. The functional expression of the P450 gene in a heterologous host will lead to efficient biotransform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48438bfb0957851eb6bc49df900148cf
https://doi.org/10.1263/jbb.100.567
https://doi.org/10.1263/jbb.100.567
Autor:
Tomoko Nakanishi, Yasuhisa Tsurumi, Shigetada Furukawa, Keisuke Ohsumi, Motoaki Nishikawa, Motohiro Hino, Kana Murakami, Michizane Hashimoto, Osamu Nakayama, Shigehiro Takase
Publikováno v:
The Journal of Antibiotics. 58:497-502
FR258900 is a novel glycogen synthesis activator produced by Fungus No. 138354. This compound was isolated from the culture broth by solvent extraction and reverse-phase column chromatography. FR258900 stimulated glycogen synthesis and glycogen synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a185babef95b55e3465ca3800d911b01
https://doi.org/10.1038/ja.2005.66
https://doi.org/10.1038/ja.2005.66
FR207944, an Antifungal Antibiotic fromChaetomiumsp. No. 217 II. Isolation and Structure Elucidation
Autor:
Akihiko Fujie, Takayoshi Kinoshita, Motohiro Hino, Seiji Yoshimura, Motoo Kobayashi, Michizane Hashimoto, Shigehiro Takase, Seiji Hashimoto, Yasuhiro Hori
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 69:1029-1032
We discovered FR207944 produced by Chaetomium sp. No. 217 in the course of screening for antifungal antibiotics from natural products. FR207944 is identical with fuscoatroside, described in the preceding paper as an anti-Aspergillus flavus agent. Det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4d27d31cfa32de32ccb0d2464698e0
https://doi.org/10.1271/bbb.69.1029
https://doi.org/10.1271/bbb.69.1029
Autor:
Motohiro Hino, Michizane Hashimoto, Kumiko Nitta, Motoo Kobayashi, Akihiko Fujie, Yasuhiro Hori, Fumie Abe, Ikuko Sato
Publikováno v:
The Journal of Antibiotics. 57:788-796
FR227244 is a novel triterpene glycoside that exhibits in vitro antifungal activity against filamentous fungi such as Aspergillus sp. and Trichophyton sp. and yeast such as Candida utilis and Candida parapsilosis but shows low activity against Candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfb5046dc8ce5f8620b6fb246043ba0
https://doi.org/10.7164/antibiotics.57.788
https://doi.org/10.7164/antibiotics.57.788