Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michiya, Sugimori"'
Autor:
Seiji Yamamoto, Masashi Muramatsu, Erika Azuma, Masashi Ikutani, Yoshinori Nagai, Hiroshi Sagara, Bon-Nyeo Koo, Satomi Kita, Erin O’Donnell, Tsuyoshi Osawa, Hiroyuki Takahashi, Ken-ichi Takano, Mitsuko Dohmoto, Michiya Sugimori, Isao Usui, Yasuhide Watanabe, Noboru Hatakeyama, Takahiro Iwamoto, Issei Komuro, Kiyoshi Takatsu, Kazuyuki Tobe, Shumpei Niida, Naoyuki Matsuda, Masabumi Shibuya, Masakiyo Sasahara
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Pericytes are believed to originate from either mesenchymal or neural crest cells. It has recently been reported that pericytes play important roles in the central nervous system (CNS) by regulating blood-brain barrier homeostasis and blood
Externí odkaz:
https://doaj.org/article/9aa3cc86afa343a8b1e09b837010f483
Autor:
Michiya Sugimori, Yumiko Hayakawa, Bruce M Boman, Jeremy Z Fields, Miharu Awaji, Hiroko Kozano, Ryoi Tamura, Seiji Yamamoto, Toru Ogata, Mitsuhiko Yamada, Shunro Endo, Masanori Kurimoto, Satoshi Kuroda
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135760 (2015)
Accumulating evidence indicates that cancer stem cells (CSCs) drive tumorigenesis. This suggests that CSCs should make ideal therapeutic targets. However, because CSC populations in tumors appear heterogeneous, it remains unclear how CSCs might be ef
Externí odkaz:
https://doaj.org/article/02b31dd9d3904299ab1817d09bb22cc7
Publikováno v:
Oncotarget
Glioblastoma resists chemotherapy then recurs as a fatal space-occupying lesion. To improve the prognosis, the issues of chemoresistance and tumor size should be addressed. Glioma stem cell (GSC) populations, a heterogeneous power-law coded populatio
Publikováno v:
Oncotarget
Glioblastoma resists chemoradiotherapy, then, recurs to be a fatal space-occupying lesion. The recurrence is caused by re-growing cell populations such as glioma stem cells (GSCs), suggesting that GSC populations should be targeted. This study addres
Autor:
Masakiyo Sasahara, Noboru Hatakeyama, Naoyuki Matsuda, Hiroshi Sagara, Mitsuko Dohmoto, Bon Nyeo Koo, Shumpei Niida, Isao Usui, Erin O'Donnell, Seiji Yamamoto, Yasuhide Watanabe, Kiyoshi Takatsu, Masashi Ikutani, Satomi Kita, Ken-ichi Takano, Erika Azuma, Kazuyuki Tobe, Tsuyoshi Osawa, Michiya Sugimori, Issei Komuro, Yoshinori Nagai, Takahiro Iwamoto, Masabumi Shibuya, Masashi Muramatsu, Hiroyuki Takahashi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Scientific Reports
Pericytes are believed to originate from either mesenchymal or neural crest cells. It has recently been reported that pericytes play important roles in the central nervous system (CNS) by regulating blood-brain barrier homeostasis and blood flow at t
Autor:
Tomohide, Hayashi, Yumiko, Hayakawa, Masaki, Koh, Takahiro, Tomita, Shoichi, Nagai, Daina, Kashiwazaki, Michiya, Sugimori, Hideki, Origasa, Satoshi, Kuroda
Publikováno v:
Neuropathology : official journal of the Japanese Society of Neuropathology. 38(2)
This study aimed to evaluate the biological features of T-lymphokine-activated killer cell-originating protein kinase (TOPK) in vitro and to assess clinical impact of TOPK on the outcome in patients with malignant glioma. TOPK protein level and TOPK
Autor:
François Guillemot, Hiroko Nakatani, Carlos Parras, Michiya Sugimori, Motoshi Nagao, Mélanie Lebel, Masato Nakafuku
Publikováno v:
Development. 135:1271-1281
Development of oligodendrocytes, myelin-forming glia in the central nervous system (CNS), proceeds on a protracted schedule. Specification of oligodendrocyte progenitors (OLPs) begins early in development, whereas their terminal differentiation occur
Autor:
Charles Hunt, Masato Nakafuku, François Guillemot, Michiya Sugimori, Carlos Parras, David H. Rowitch
Publikováno v:
The Journal of Neuroscience. 27:4233-4242
The bHLH (basic helix-loop-helix) transcription factor Mash1 is best known for its role in the regulation of neurogenesis. However, Mash1 is also expressed in oligodendrocyte precursors and has recently been shown to promote the generation of oligode
Autor:
Seiji Yamamoto, Jeremy Z. Fields, Satoshi Kuroda, Masanori Kurimoto, Miharu Awaji, Shunro Endo, Yumiko Hayakawa, Michiya Sugimori, Toru Ogata, Bruce M. Boman, Hiroko Kozano, Mitsuhiko Yamada, Ryoi Tamura
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135760 (2015)
PLoS ONE
PLoS ONE
Background Accumulating evidence indicates that cancer stem cells (CSCs) drive tumorigenesis. This suggests that CSCs should make ideal therapeutic targets. However, because CSC populations in tumors appear heterogeneous, it remains unclear how CSCs
Autor:
Toshio Kitamura, Michiya Sugimori, Hidetaka Kosako, Motoshi Nagao, Gerry Weinmaster, Hirofumi Nakatomi, Masato Nakafuku, Kozo Nakamura, Naoya Yamamoto, Shin Ichi Yamamoto, Yo-ichi Nabeshima, Hirohide Takebayashi
Publikováno v:
Scopus-Elsevier
Recent studies have demonstrated that neural stem cells and other progenitors are present in the adult CNS. Details of their properties, however, remain poorly understood. Here we examined the properties and control mechanisms of neural progenitors i