Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Michishige Harada"'
Autor:
Nyambayar Dashtsoodol, Tomokuni Shigeura, Ritsuko Ozawa, Michishige Harada, Satoshi Kojo, Takashi Watanabe, Haruhiko Koseki, Manabu Nakayama, Osamu Ohara, Masaru Taniguchi
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153347 (2016)
Invariant Vα14 natural killer T (NKT) cells, characterized by the expression of a single invariant T cell receptor (TCR) α chain encoded by rearranged Trav11 (Vα14)-Traj18 (Jα18) gene segments in mice, and TRAV10 (Vα24)-TRAJ18 (Jα18) in humans,
Externí odkaz:
https://doaj.org/article/24ca0c137363450ba05b3819008aee46
Autor:
Yu Adachi, Michishige Harada, Miho Tanaka, Takashi Tanaka, Masaki Hikida, Toshitada Takemori, Tommy Terooatea, Akiko Sugimoto-Ishige, Yoshimasa Takahashi, Peter D. Burrows
Publikováno v:
International Immunology. 33:79-90
In T cell-dependent antibody responses, some of the activated B cells differentiate along extrafollicular pathways into low-affinity memory and plasma cells, whereas others are involved in subsequent germinal center (GC) formation in follicular pathw
Autor:
Toshitada Takemori, Akiko Sugimoto-Ishige, Hironori Nishitsuji, Yushi Futamura, Michishige Harada, Tomomi Kimura-Someya, Takehisa Matsumoto, Teruki Honma, Miho Tanaka, Masami Yaguchi, Kyoichi Isono, Haruhiko Koseki, Hiroyuki Osada, Daiki Miki, Takashi Saito, Takashi Tanaka, Takehiro Fukami, Toshio Goto, Mikako Shirouzu, Kunitada Shimotohno, Kazuaki Chayama
Publikováno v:
Journal of virology. 96(5)
Hepatitis B virus (HBV) infects 240 million people worldwide. Current therapy profoundly suppresses HBV replication but requires long-term maintenance therapy. Therefore, there is still a medical need for an efficient HBV cure. HBV enters host cells
Autor:
Masami Yaguchi, Toshitada Takemori, Fumihiko Ishikawa, Mikako Shirouzu, Issay Kitabayashi, Takehisa Matsumoto, Michishige Harada, Shigeyuki Yokoyama, Miho Tanaka, Akiko Ishige
Publikováno v:
Journal of Immunological Methods. 464:74-86
Antibody-based therapeutic strategies have become recognized as useful clinical options in several types of cancer, often with the expectation that such therapies will trigger target cell elimination via antibody-dependent cellar cytotoxicity (ADCC)
Autor:
Satoshi Kojo, Takashi Watanabe, Michishige Harada, Minako Aihara, Ritsuko Ozawa, Tomokuni Shigeura, Nyambayar Dashtsoodol, Masaru Taniguchi, Takaho A. Endo, Osamu Ohara
Publikováno v:
Nature Immunology. 18:274-282
Although invariant Vα14+ natural killer T cells (NKT cells) are thought to be generated from CD4+CD8+ double-positive (DP) thymocytes, the developmental origin of CD4-CD8- double-negative (DN) NKT cells still remains unresolved. Here we provide defi
Publikováno v:
Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
Natural Killer T (NKT) cells are unique lymphocytes characterized by their expression of a single invariant antigen receptor encoded by Vα14Jα18 in mice and Vα24Jα18 in humans, which recognizes glycolipid antigens in association with the monomorp
Autor:
Nyambayar, Dashtsoodol, Tomokuni, Shigeura, Minako, Aihara, Ritsuko, Ozawa, Satoshi, Kojo, Michishige, Harada, Takaho A, Endo, Takashi, Watanabe, Osamu, Ohara, Masaru, Taniguchi
Publikováno v:
Nature immunology. 18(3)
Although invariant V
Autor:
Tatsuya Atsumi, Nao Suzuki, Masaru Taniguchi, Yusuke Sotomaru, Muhammad Baghdadi, Ken-ichiro Seino, Haruka Wada, Satoshi Kojo, Hiroaki Honda, Masatoshi Kanda, Yuu Usui, Hiroyuki Yamanaka, Michishige Harada
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Invariant natural killer T (iNKT) cells are a subset of innate-like T cells that act as important mediators of immune responses. In particular, iNKT cells have the ability to immediately produce large amounts of IFN-γ upon activation and thus initia
Autor:
Ross Lazarus, Christine A. Sorkness, Weiliang Qiu, Jessica Lasky-Su, Qing Ling Duan, Barbara J. Klanderman, Stephen P. Peters, Stanley J. Szefler, Mayumi Tamari, Fernando D. Martinez, John J. Lima, Augusto A. Litonjua, Amy Murphy, Blanca E. Himes, Jody S. Sylvia, Tomomitsu Hirota, Kelan G. Tantisira, David T. Mauger, Stephen C. Lazarus, Scott T. Weiss, Yusuke Nakamura, Christoph Lange, Robert F. Lemanske, Michishige Harada
Publikováno v:
New England Journal of Medicine. 365:1173-1183
The response to treatment for asthma is characterized by wide interindividual variability, with a significant number of patients who have no response. We hypothesized that a genomewide association study would reveal novel pharmacogenetic determinants
Autor:
Akihiro Kojima, Yoko Osawa, Yusuke Nakamura, Shigeharu Fujieda, Masafumi Sakashita, Tomomitsu Hirota, Mayumi Tamari, Tatsuhiko Tsunoda, Yoshimasa Imoto, Dai Suzuki, Reiichiro Nakamichi, Michishige Harada, Masayuki Okamoto, Seita Kubo
Publikováno v:
International Archives of Allergy and Immunology. 151:255-261
Background: Allergic rhinitis (AR) is recognized as a major health problem worldwide, and its prevalence depends on the age range of the subjects. The aims of this study were to determine the current prevalence of AR, effects of age on the prevalence