Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Michiru Yoshimizu"'
Autor:
Tim Edmunds, Naho Ohyanagi, Kohji Itoh, Kaori Fujishima, Kobayashi Toshihide, Tadayasu Togawa, Daisuke Tsuji, Masahiko Ikekita, Kanako Sugawara, Ikuo Kawashima, Michiru Yoshimizu, Youichi Tajima, Sei-ichi Aikawa, Fumiko Matsuzawa, Kunihiko Iwamoto, Toshihiro Suzuki, Hitoshi Sakuraba, Kazuki Ohno
Publikováno v:
Clinica Chimica Acta. 391:68-73
Background Recently, enzyme enhancement therapy (EET) for Pompe disease involving imino sugars, which act as potential inhibitors of acid α-glucosidases in vitro , to improve the stability and/or transportation of mutant acid α-glucosidases in cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2293f690368010fe83c4ecfdf0f3f5c
https://doi.org/10.1016/j.cca.2008.02.014
https://doi.org/10.1016/j.cca.2008.02.014
Autor:
Hitoshi Sakuraba, Youichi Tajima, Sei Ichi Aikawa, Fumiko Matsuzawa, Michiru Yoshimizu, Toshika Okumiya, Takahiro Tsukimura, Masahiko Ikekita, Akihiko Tsuji, Seiichi Tsujino, Tim Edmunds
Publikováno v:
Journal of human genetics. 52(11)
We constructed structural models of the catalytic domain and the surrounding region of human wild-type acid alpha-glucosidase and the enzyme with amino acid substitutions by means of homology modeling, and examined whether the amino acid replacements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7640b676c1a5f09cc1f36dcb0d82b58b
https://pubmed.ncbi.nlm.nih.gov/17805474
https://pubmed.ncbi.nlm.nih.gov/17805474