Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Michio SUGITA"'
Autor:
Paul A. Bunn, Mark W. Geraci, Fred R. Hirsch, Wilbur A. Franklin, Anna Barón, Chan Zeng, Razvan Lapadat, Michio Sugita, Samir E. Witta, Barbara A. Helfrich, Christopher D. Coldren
Tyrosine kinase inhibitors (TKI) of the epidermal growth factor receptor (EGFR) produce objective responses in a minority of patients with advanced-stage non–small cell lung cancer (NSCLC), and about half of all treated patients progress within 6 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112ce840588081f9340ec2546303707a
https://doi.org/10.1158/1541-7786.c.6542668
https://doi.org/10.1158/1541-7786.c.6542668
Autor:
Paul A. Bunn, Mark W. Geraci, Fred R. Hirsch, Wilbur A. Franklin, Anna Barón, Chan Zeng, Razvan Lapadat, Michio Sugita, Samir E. Witta, Barbara A. Helfrich, Christopher D. Coldren
Supplementary Table S2 from Baseline Gene Expression Predicts Sensitivity to Gefitinib in Non–Small Cell Lung Cancer Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2808550279f57f6a96e93409150888e0
https://doi.org/10.1158/1541-7786.22520524.v1
https://doi.org/10.1158/1541-7786.22520524.v1
Autor:
Paul A. Bunn, Mark W. Geraci, Fred R. Hirsch, Wilbur A. Franklin, Anna Barón, Chan Zeng, Razvan Lapadat, Michio Sugita, Samir E. Witta, Barbara A. Helfrich, Christopher D. Coldren
Supplementary Table S1 from Baseline Gene Expression Predicts Sensitivity to Gefitinib in Non–Small Cell Lung Cancer Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712e6d8fef6b52f6307fa6099fb96b3f
https://doi.org/10.1158/1541-7786.22520527.v1
https://doi.org/10.1158/1541-7786.22520527.v1
Autor:
Raphael A. Nemenoff, Mark Geraci, Paul A. Bunn, Lynn Heasley, Roger Powell, Timothy C. Kennedy, Greg Hickey, Anna E. Baron, Xian Lu, David J. Orlicky, Christopher Coldren, Charlene O'Shea, Peter J. Koch, Storey Wilson, Adrie van Bokhoven, Jessica M. Malloy, Elizabeth J. Donald, Mary C. O'Keefe, Meredith A. Tennis, Lori D. Dwyer-Nield, Micah B. Friedman, York E. Miller, Robert L. Keith, Michio Sugita, Wilbur A. Franklin, Michael G. Edwards, Daniel T. Merrick
Persistent bronchial dysplasia is associated with increased risk of developing invasive squamous cell carcinoma (SCC) of the lung. In this study, we hypothesized that differences in gene expression profiles between persistent and regressive bronchial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea91707d0c49730f588b90ad933b0c7
https://doi.org/10.1158/0008-5472.c.6512359.v1
https://doi.org/10.1158/0008-5472.c.6512359.v1
Autor:
Raphael A. Nemenoff, Mark Geraci, Paul A. Bunn, Lynn Heasley, Roger Powell, Timothy C. Kennedy, Greg Hickey, Anna E. Baron, Xian Lu, David J. Orlicky, Christopher Coldren, Charlene O'Shea, Peter J. Koch, Storey Wilson, Adrie van Bokhoven, Jessica M. Malloy, Elizabeth J. Donald, Mary C. O'Keefe, Meredith A. Tennis, Lori D. Dwyer-Nield, Micah B. Friedman, York E. Miller, Robert L. Keith, Michio Sugita, Wilbur A. Franklin, Michael G. Edwards, Daniel T. Merrick
Supplemental table S1 documents comparability between final groupings of baseline biopsies used for gene expression comparisons between persistent and regressive sites demonstrating comparability in all key histologic and clinical variables with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50980f3916c13cb411e1361af5b422aa
https://doi.org/10.1158/0008-5472.22426510
https://doi.org/10.1158/0008-5472.22426510
Autor:
Tatsuo Ohira, Kinya Furukawa, Hidenobu Takahashi, Jun Matsubayashi, Fred R. Hirsch, Wilbur A. Franklin, Osamu Uchida, Norihiko Ikeda, Eiji Nakajima, Youhei Kawaguchi, Michio Sugita
Epidermal growth factor receptor (EGFR) is the most important driver gene of non-small cell lung cancer (NSCLC) as EGFR mutations determine the efficacy of EGFR tyrosine kinase inhibitor (EGFR-TKI) therapy. In the present study, the comprehensive abi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe82e52d9d95b3bda4fb7119c514775
https://europepmc.org/articles/PMC6507309/
https://europepmc.org/articles/PMC6507309/
Autor:
Micah Friedman, Lynn E. Heasley, Michael G. Edwards, Michio Sugita, Elizabeth J. Donald, Jessica M. Malloy, Meredith A. Tennis, Raphael A. Nemenoff, Robert L. Keith, Peter Koch, Roger Powell, Wilbur A. Franklin, Charlene O'Shea, David J. Orlicky, Storey Wilson, Paul A. Bunn, Adrie van Bokhoven, Daniel T. Merrick, Lori D. Dwyer-Nield, Timothy C. Kennedy, Mark W. Geraci, Xian Lu, Mary C. O'Keefe, Christopher D. Coldren, Greg Hickey, Anna E. Barón, York E. Miller
Persistent bronchial dysplasia is associated with increased risk of developing invasive squamous cell carcinoma (SCC) of the lung. In this study, we hypothesized that differences in gene expression profiles between persistent and regressive bronchial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f053fd95c915f6359b374cc8b99f51
https://europepmc.org/articles/PMC6147150/
https://europepmc.org/articles/PMC6147150/
Autor:
Michio Sugita, Norihiko Ikeda, E. Nakajima, Hidenobu Takahashi, Yohei Kawaguchi, Wilbur A. Franklin, Kinya Furukawa, Fred R. Hirsch, Tatsuo Ohira
Publikováno v:
Journal of Thoracic Oncology. 12:S2134-S2135
Autor:
Wilbur A. Franklin, Jerry Haney, Lynne T. Bemis, Michio Sugita, Antonio Jimeno, Wells A. Messersmith
Publikováno v:
The Journal of Molecular Diagnostics. 12:43-50
Treatment of colon carcinoma with the anti-epidermal growth factor receptor antibody Cetuximab is reported to be ineffective in KRAS-mutant tumors. Mutation testing techniques have therefore become an urgent concern. We have compared three methods fo
Autor:
E. Nakajima, Paul A. Bunn, D. K. Birks, Marileila Varella-Garcia, Wilbur A. Franklin, Fred R. Hirsch, Jerry Haney, Glen J. Weiss, Lynne T. Bemis, William A. Robinson, Harubumi Kato, Michio Sugita, Barbara Helfrich
Publikováno v:
Annals of Oncology. 19:1053-1059
Background Allelic loss in chromosome 3p is one of the most frequent and earliest genetic events in lung carcinogenesis. We investigated if the loss of microRNA-128b, a microRNA located on chromosome 3p and a putative regulator of epidermal growth fa