Zobrazeno 1 - 10 of 67 pro vyhledávání: '"Michio SUGITA"'
1
Data from Baseline Gene Expression Predicts Sensitivity to Gefitinib in Non–Small Cell Lung Cancer Cell Lines
Autor: Paul A. Bunn, Mark W. Geraci, Fred R. Hirsch, Wilbur A. Franklin, Anna Barón, Chan Zeng, Razvan Lapadat, Michio Sugita, Samir E. Witta, Barbara A. Helfrich, Christopher D. Coldren
Tyrosine kinase inhibitors (TKI) of the epidermal growth factor receptor (EGFR) produce objective responses in a minority of patients with advanced-stage non–small cell lung cancer (NSCLC), and about half of all treated patients progress within 6 w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112ce840588081f9340ec2546303707a
https://doi.org/10.1158/1541-7786.c.6542668
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5
Frequency and significance of epidermal growth factor receptor mutations detected by PCR methods in patients with non-small cell lung cancer
Autor: Tatsuo Ohira, Kinya Furukawa, Hidenobu Takahashi, Jun Matsubayashi, Fred R. Hirsch, Wilbur A. Franklin, Osamu Uchida, Norihiko Ikeda, Eiji Nakajima, Youhei Kawaguchi, Michio Sugita
Epidermal growth factor receptor (EGFR) is the most important driver gene of non-small cell lung cancer (NSCLC) as EGFR mutations determine the efficacy of EGFR tyrosine kinase inhibitor (EGFR-TKI) therapy. In the present study, the comprehensive abi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe82e52d9d95b3bda4fb7119c514775
https://europepmc.org/articles/PMC6507309/
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8
KRAS Mutation
Autor: Wilbur A. Franklin, Jerry Haney, Lynne T. Bemis, Michio Sugita, Antonio Jimeno, Wells A. Messersmith
Publikováno v: The Journal of Molecular Diagnostics. 12:43-50
Treatment of colon carcinoma with the anti-epidermal growth factor receptor antibody Cetuximab is reported to be ineffective in KRAS-mutant tumors. Mutation testing techniques have therefore become an urgent concern. We have compared three methods fo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3db5a7f3a6f55309f678e05c4b0c0bb8
https://doi.org/10.2353/jmoldx.2010.080131
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9
EGFR regulation by microRNA in lung cancer: correlation with clinical response and survival to gefitinib and EGFR expression in cell lines
Autor: E. Nakajima, Paul A. Bunn, D. K. Birks, Marileila Varella-Garcia, Wilbur A. Franklin, Fred R. Hirsch, Jerry Haney, Glen J. Weiss, Lynne T. Bemis, William A. Robinson, Harubumi Kato, Michio Sugita, Barbara Helfrich
Publikováno v: Annals of Oncology. 19:1053-1059
Background Allelic loss in chromosome 3p is one of the most frequent and earliest genetic events in lung carcinogenesis. We investigated if the loss of microRNA-128b, a microRNA located on chromosome 3p and a putative regulator of epidermal growth fa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4af8e430ad3d1232bfb7f1112e47c68
https://doi.org/10.1093/annonc/mdn006
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10
Overexpression of vascular endothelial growth factor and its receptors in bronchial dypslasia demonstrated by quantitative RT-PCR analysis
Autor: Michio Sugita, Jerry Haney, Daniel T. Merrick, T. Kennedy, Wilbur A. Franklin, Robert L. Keith, Sheila Petrunich, York E. Miller
Publikováno v: Lung Cancer. 48:31-45
Neoangiogenesis is required for the growth of invasive lung carcinoma, however, the role of angiogenesis in the progression of premalignant changes to carcinoma of the lung is less clear. We have evaluated vascular endothelial growth factor (VEGF) ex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9371d8f0d2f43c0fd2f57c285acbeac9
https://doi.org/10.1016/j.lungcan.2004.07.049
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