Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michiko Yamato"'
Autor:
Toshinori Agatsuma, Yuki Abe, Takashi Nakada, Ichiro Hayakawa, Tetsuo Aida, Tomoko Shibutani, Yumi Nishiya, Akiko Watanabe, Kazuyoshi Kumagai, Chiharu Hattori, Takanori Maejima, Jun Hasegawa, Michiko Yamato
Supplementary Data from DS-7300a, a DNA Topoisomerase I Inhibitor, DXd-Based Antibody–Drug Conjugate Targeting B7-H3, Exerts Potent Antitumor Activities in Preclinical Models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2555c866d4671115aaf3d352455d62eb
https://doi.org/10.1158/1535-7163.22521898.v1
https://doi.org/10.1158/1535-7163.22521898.v1
Autor:
Toshinori Agatsuma, Yuki Abe, Takashi Nakada, Ichiro Hayakawa, Tetsuo Aida, Tomoko Shibutani, Yumi Nishiya, Akiko Watanabe, Kazuyoshi Kumagai, Chiharu Hattori, Takanori Maejima, Jun Hasegawa, Michiko Yamato
B7-H3 is overexpressed in various solid tumors and has been considered as an attractive target for cancer therapy. Here, we report the development of DS-7300a, a novel B7-H3–targeting antibody–drug conjugate with a potent DNA topoisomerase I inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a31bd9f9c43f7e981e6be14ca30c4b1
https://doi.org/10.1158/1535-7163.c.6543217
https://doi.org/10.1158/1535-7163.c.6543217
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Masaaki Miyazawa, Kenji Hirotani, Michiko Yamato, Hiroyasu Kaneda, Yoshikazu Hasegawa, Keita Kudo, Takafumi Okabe, Yasutaka Chiba, Kazuko Sakai, Osamu Maenishi, Sigeki Kato, Masayuki Takeda, Hidetoshi Hayashi, Kaoru Tanaka, Takayuki Takahama, Naoki Takegawa, Ryoji Kato, Hitomi Sakai, Shiki Takamura, Koji Haratani, Kimio Yonesaka
Cox proportional hazard model for PFS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505dd07e89ca0903d27a29cfc2bd0676
https://doi.org/10.1158/1078-0432.22464515.v1
https://doi.org/10.1158/1078-0432.22464515.v1
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Masaaki Miyazawa, Kenji Hirotani, Michiko Yamato, Hiroyasu Kaneda, Yoshikazu Hasegawa, Keita Kudo, Takafumi Okabe, Yasutaka Chiba, Kazuko Sakai, Osamu Maenishi, Sigeki Kato, Masayuki Takeda, Hidetoshi Hayashi, Kaoru Tanaka, Takayuki Takahama, Naoki Takegawa, Ryoji Kato, Hitomi Sakai, Shiki Takamura, Koji Haratani, Kimio Yonesaka
Effect of using a combination of targeting B7-H3 and PD-L1 on body weight in the murine tumor model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d23b233794e7c93aca35e20ccea76fe
https://doi.org/10.1158/1078-0432.22464524
https://doi.org/10.1158/1078-0432.22464524
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Masaaki Miyazawa, Kenji Hirotani, Michiko Yamato, Hiroyasu Kaneda, Yoshikazu Hasegawa, Keita Kudo, Takafumi Okabe, Yasutaka Chiba, Kazuko Sakai, Osamu Maenishi, Sigeki Kato, Masayuki Takeda, Hidetoshi Hayashi, Kaoru Tanaka, Takayuki Takahama, Naoki Takegawa, Ryoji Kato, Hitomi Sakai, Shiki Takamura, Koji Haratani, Kimio Yonesaka
Purpose: Anti-programmed-death-1 (PD-1) immunotherapy improves survival in non–small cell lung cancer (NSCLC), but some cases are refractory to treatment, thereby requiring alternative strategies. B7-H3, an immune-checkpoint molecule, is expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95980b3d3cae0019d5b82f348c03f737
https://doi.org/10.1158/1078-0432.c.6525734
https://doi.org/10.1158/1078-0432.c.6525734
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Masaaki Miyazawa, Kenji Hirotani, Michiko Yamato, Hiroyasu Kaneda, Yoshikazu Hasegawa, Keita Kudo, Takafumi Okabe, Yasutaka Chiba, Kazuko Sakai, Osamu Maenishi, Sigeki Kato, Masayuki Takeda, Hidetoshi Hayashi, Kaoru Tanaka, Takayuki Takahama, Naoki Takegawa, Ryoji Kato, Hitomi Sakai, Shiki Takamura, Koji Haratani, Kimio Yonesaka
The B7-H3 staining pattern for diagnosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cf935d279d751a45ffd6d513c4991e
https://doi.org/10.1158/1078-0432.22464527.v1
https://doi.org/10.1158/1078-0432.22464527.v1
Autor:
Kazuhiko Nakagawa, Kazuto Nishio, Masaaki Miyazawa, Kenji Hirotani, Michiko Yamato, Hiroyasu Kaneda, Yoshikazu Hasegawa, Keita Kudo, Takafumi Okabe, Yasutaka Chiba, Kazuko Sakai, Osamu Maenishi, Sigeki Kato, Masayuki Takeda, Hidetoshi Hayashi, Kaoru Tanaka, Takayuki Takahama, Naoki Takegawa, Ryoji Kato, Hitomi Sakai, Shiki Takamura, Koji Haratani, Kimio Yonesaka
Effect of PD-L1 and B7-H3 expression on response rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642e783b8bea9f568eb158457b321a1c
https://doi.org/10.1158/1078-0432.22464518
https://doi.org/10.1158/1078-0432.22464518
Autor:
Michiko Yamato, Jun Hasegawa, Takanori Maejima, Chiharu Hattori, Kazuyoshi Kumagai, Akiko Watanabe, Yumi Nishiya, Tomoko Shibutani, Tetsuo Aida, Ichiro Hayakawa, Takashi Nakada, Yuki Abe, Toshinori Agatsuma
Publikováno v:
Molecular Cancer Therapeutics. 21:635-646
B7-H3 is overexpressed in various solid tumors and has been considered as an attractive target for cancer therapy. Here, we report the development of DS-7300a, a novel B7-H3–targeting antibody–drug conjugate with a potent DNA topoisomerase I inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3759d969aadf128e10d9488ca610c7
https://doi.org/10.1158/1535-7163.mct-21-0554
https://doi.org/10.1158/1535-7163.mct-21-0554
Autor:
Koji Haratani, Yasutaka Chiba, Shiki Takamura, Takafumi Okabe, Kenji Hirotani, Hiroyasu Kaneda, Michiko Yamato, Kaoru Tanaka, Shigeki Kato, Kazuhiko Nakagawa, Kazuto Nishio, Hidetoshi Hayashi, Yoshikazu Hasegawa, Masayuki Takeda, Kazuko Sakai, Kimio Yonesaka, Masaaki Miyazawa, Osamu Maenishi, Ryoji Kato, Naoki Takegawa, Takayuki Takahama, Hitomi Sakai, Keita Kudo
Publikováno v:
Clinical Cancer Research. 24:2653-2664
Purpose: Anti-programmed-death-1 (PD-1) immunotherapy improves survival in non–small cell lung cancer (NSCLC), but some cases are refractory to treatment, thereby requiring alternative strategies. B7-H3, an immune-checkpoint molecule, is expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716f541903486e8cf68ac39109328d79
https://doi.org/10.1158/1078-0432.ccr-17-2852
https://doi.org/10.1158/1078-0432.ccr-17-2852
Autor:
Mitsuhiro Yazawa, Kenji Hirotani, Toshinori Agatsuma, Shu Takahashi, Akiko Nagase-Zembutsu, Michiko Yamato, Junko Yamaguchi, Makoto Yoshida, Takehiko Takata, Keisuke Fukuchi
Publikováno v:
Cancer Science
B7-H3 is highly overexpressed in a variety of human clinical tumors, and its expression is significantly associated with poor outcomes. In our study, we aimed to develop new antitumor mAbs by employing cancer cell immunization, and succeeded in gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69b2e34a377b70667db12115db3ad8a
http://europepmc.org/articles/PMC4970835
http://europepmc.org/articles/PMC4970835