Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michiko Hayasaka"'
Publikováno v:
Development, Growth & Differentiation. 56:653-668
A mouse line carrying a lacZ transgene driven by the human EEF1A1/EF1 alpha promoter was established. Although the promoter is known to show ubiquitous activity, only paternal transgene alleles were expressed, resulting in a transgene imprinting. At
Publikováno v:
genesis. 49:803-810
The homeobox gene Lbx1 not only plays critical roles in myogenesis and neurogenesis during embryonic development but is also expressed in activated satellite cells of adult mice. To address the potential postnatal functions of Lbx1, we generated cond
Autor:
Kazuma Tomizuka, Takeyoshi Yamashita, Motoo Takahashi, Yuri Shibasaki, Kazunori Hanaoka, Nobuaki Etoh, Makoto Kakitani, Michiko Hayasaka
Publikováno v:
Biochemical and Biophysical Research Communications. 381:482-486
NaPi-IIb encodes a Na(+)-dependent Pi co-transporter, which is expressed in various adult tissues and mediates transport of extracellular Pi ions coupling with Na(+) ion. To define the role of NaPi-IIbin vivo, NaPi-IIb gene deficient mice were genera
Autor:
Michiko Hayasaka, Seiji Hitoshi, Kumiko Ui-Tei, Tomoaki Nishimura, Akiko Kinoshita-Toyoda, Kazunari Hanaoka, Kazuhiro Ikenaka, Hidenao Toyoda, Kazuhiko Okishio, Kaoru Saigo, Yasuo Suda, Norihiko Sasaki, Shoko Nishihara
Publikováno v:
Journal of Biological Chemistry. 283:3594-3606
Embryonic stem (ES) cell self-renewal and pluripotency are maintained by several signaling cascades and by expression of intrinsic factors, such as Oct3/4 and Nanog. The signaling cascades are activated by extrinsic factors, such as leukemia inhibito
Publikováno v:
Journal of Cell Science. 120:4178-4187
Satellite cells are usually mitotically quiescent muscle stem cells, located between the sarcolemma and the basement membrane of muscle fibers. When muscles are damaged, satellite cells become activated, proliferate and differentiate to form multinuc
Autor:
Kazunori Hanaoka, Michiko Hayasaka, Akiko Ueda, Haruko Ikeda, Makoto Kakitani, Kazuma Tomizuka, Hiroe Kudoh
Publikováno v:
Biochemical and Biophysical Research Communications. 328:507-516
Duchenne muscular dystrophy (DMD) is caused by mutation in the 2.4-Mb dystrophin (DMD) gene . This gene encodes a number of tissue-specific isoforms of dystrophin generated by transcription from at least seven promoters and also by alternative splici
Autor:
Yumi Mizukura, Kanae Sekine, Kazunori Hanaoka, Yasuhito Nakagawa, Hirotaka Imai, Takeo Kitamoto, Fumi Hirao, Taro Sakamoto, Makoto Saito, Michiko Hayasaka
Publikováno v:
Biochemical and Biophysical Research Communications. 305:278-286
Phospholipid hydroperoxide glutathione peroxidase (PHGPx) is the only known intracellular antioxidant enzyme that can directly reduce lipid hydroperoxide in membrane. Mitochondrial and non-mitochondrial PHGPx and sperm nuclei GPx are transcribed from
Autor:
Michiko Hayasaka, Koji Uchiyama, Naomichi Nishimura, Ayako Yamamoto, Tomoka Nara, Tatsuro Yamamoto, Kazunori Hanaoka
Publikováno v:
Developmental neuroscience. 36(5)
Spock3/Testican-3 is a nervous system-expressed heparan sulfate proteoglycan belonging to a subgroup of the BM-40/SPARC/osteonectin family, the role of which in brain development is unclear. Because Spock1, a member of the Spock family, inhibits thei
Publikováno v:
General Pharmacology: The Vascular System. 30:103-107
1. 1. Experiments were designed to study the roles of protein kinase C in carbachol- and pilocarpine-induced contraction and the increase in cytosolic Ca2+ concentration ([Ca2+]i) in guinea pig ileal longitudinal muscle. 2. 2. The protein kinase C in
Autor:
Michiko Hayasaka, Yo-ichi Nabeshima, Hirohisa Katoh, Shun-ichi Takewaki, Tsuyoshi Noguchi, Akira Miyagishi, Ryozo Nagai, Yoshio Yazaki, Yumi Fujimori, Yukio Hiroi, Makoto Kuro-o, Kazunori Hanaoka
Publikováno v:
Circulation Research. 76:148-153
Abstract Essential hypertension is one of the most common diseases that exacerbate the risk of cardiovascular or cerebrovascular attacks. Although the etiology of essential hypertension remains unclear, recent investigations have revealed that an enh