Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Michiko Amao"'
Publikováno v:
Analytical Biochemistry. 472:45-51
Glucagon-like peptide-1 (GLP-1) is an incretin peptide that regulates islet hormone secretion. During recent years, incretin-based therapies have been widely used for patients with type 2 diabetes. GLP-1 peptides undergo N- and C-terminal processing
Autor:
Michiko Amao, Junkichi Miura, Junko Yamazaki, Takefumi Yokokura, Toshihiko Ando, Shintaro Kubo, Kazuo Hirayama, Hiroshi Miyano, Yushi Harada, Shinichi Ozawa, Hiroo Yoshida, Naoko Kageyama, Takashi Oonuki, Mina Nakamura, Kazutaka Shimbo
Publikováno v:
Biomedical Chromatography. 24:683-691
An automated method for high-throughput amino acid analysis, using precolumn derivatization high-performance liquid chromatography/electrospray mass spectrometry (HPLC/ESI-MS), was developed and evaluated. The precolumn derivatization step was perfor
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 23:3119-3131
Human serum albumin was purified by size-exclusion liquid chromatography. The glycated albumin in the effluent was selectively measured by a post-column reaction detector. The selective reaction mechanism is to measure the amount of Amadori form of g
Publikováno v:
The FASEB Journal. 22
Autor:
Keigi Chin, Riho Kodama, Yasuko Kawamata, Sakino Toue, Takeshi Kimura, Ryosei Sakai, Michiko Amao
Publikováno v:
The FASEB Journal. 22
Publikováno v:
The FASEB Journal. 21
Publikováno v:
The Journal of nutrition. 136
Although many animal studies have reported that dietary excess of methionine causes toxic changes including growth suppression and hemolytic anemia, the biochemical mechanism and biomarkers for methionine toxicity have not been well elucidated. The p
Publikováno v:
The Journal of nutrition. 135
Changes were investigated in plasma metabolites and physiological and toxicological variables in rats fed for 2 wk on a basal diet or diets with 1.5, 5, 10, 15, and 30% added leucine. In the same experiment, the changes in gene expression in livers o
Autor:
Riho Kodama, Makoto Miura, Takeshi Kimura, Ryosei Sakai, Michiko Amao, Yasushi Noguchi, Sakino Toue
Publikováno v:
The Journal of nutrition. 134
We report on research progress on two approaches that may be useful in determining the upper adequacy range for macronutrients such as amino acids. One approach was to attempt to identify "toxic metabolites" that were responsible for toxicity or biom
Publikováno v:
European journal of immunology. 33(4)
The redox status of macrophages (M phi), indexed by intracellular content of glutathione (icGSH), varies sequentially along with disease progression in nonobese diabetic mice. At the stage of early insulitis, M phi skew to oxidative M phi (OM phi) wi