Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Michiji Komoto"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1256:166-174
Human lens accumulates gangliosides in association with aging and senile cataract progression. In this study we purified and characterized five major gangliosides in human cataractous lenses. Structural analyses and immunological studies revealed the
Publikováno v:
Experimental Eye Research. 60:317-323
We previously reported that human lens accumulates gangliosides in association with aging and senile cataract progression. Structural analysis revealed that gangliosides in human cataractous lenses were composed of ganglio-series gangliosides, such a
Publikováno v:
Experimental Eye Research. 60:193-198
Neutral glycosphingolipids were purified from non-cataractous lenses of Sprague-Dawley rats by a combination of solvent extraction, Folch's partition, and column chromatography using DEAE-Sephadex and Iatrobeads. Six major GSLs from monohexosylcerami
Autor:
Motonori Hoshi, Tatsuyuki Okinaga, Nobuyuki Saito, Ichiro Nishiyama, Manabu Ogiso, Michiji Komoto
Publikováno v:
Glycobiology. 5:187-194
Rat lens was found to contain several neutral and acidic glycosphingolipids in lens epithelia, cortex and nucleus, and showed developmental changes in their content and localization. TLC-immunostaining of gangliosides revealed the enrichment of some
Publikováno v:
Experimental Eye Research. 59:653-664
The carbohydrate epitope Gal alpha 1-3Gal-R (alpha-galactosyl epitope), which is detectable by its binding with Bandeiraea simplicifolia-IB4 lectin, was found in glycosphingolipids (GSLs), both neutral and acidic (gangliosides), from lens tissues of
Publikováno v:
Glycobiology. 7(5)
The functions of glycosphingolipids, especially those containing the alpha-galactosyl epitope, were investigated during the development and differentiation of rat lens. Glycosphingolipids in embryonic lens tissue were mainly composed of neolacto-seri
Publikováno v:
Biochimica et biophysica acta. 1315(1)
In Japanese monkey lenses, 3 H-labeled fucose and N -acetylneuraminic acid were enzymatically transferred to neolactotetraosylceramide (nLc4) and III 3 FucnLc4, respectively, suggesting the presence of a synthetic pathway of IV 3 NeuACIII 3 FucnLc4 v
Autor:
Manabu Ogiso, Toshiyuki Matsuno, Michiji Komoto, Yuji Koide, Hideo Kubo, Atsushi Irie, Motonori Hoshi
Publikováno v:
The Journal of biological chemistry. 268(18)
Neutral glycosphingolipids were purified from human senile cataractous lenses by a combination of solvent extraction, Folch's partition, acetylation, and column chromatography using DEAE-Sephadex and Iatrobeads. Six major glycosphingolipids (A-F) fro
Publikováno v:
The Journal of biological chemistry. 267(10)
A glycosphingolipid that reacted positively to anti-stage-specific embryonic antigen-1 (SSEA-1) antiserum accumulated in human lens in association with aging and senile cataract formation. Since this antiserum recognizes Lewis(x) (Le(x)) structure, G
Autor:
Nobuyuki Saito, Takanobu Hidaka, Michiji Komoto, Masahiko Kishi, Teruyuki Kurihara, Masao Kinoshita
Publikováno v:
Journal of the neurological sciences. 99(1)
An X chromosome-linked mouse mutant (mdx) has been investigated as an animal model of Duchenne's muscular dystrophy, and has been found to have the same defect of dystrophin in the muscle surface membrane. Intracellular recordings from the mdx mouse