Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michihiro Fujino"'
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
In recent years, the clinical importance of immunotherapy has been demonstrated in the treatment of extensive-stage small-cell lung cancer (ES-SCLC). However, immune checkpoint inhibitors (ICIs) have been shown to cause immune-related adverse events
Externí odkaz:
https://doaj.org/article/436cd5e16f2944f5954373c5fd6425d3
Autor:
Tetsuyuki, Igarashi, Kazuya, Ishiguro, Yoshitake, Takagi, Michihiro, Fujino, Masayuki, Tsujisaki
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 61(11)
When a 74-year-old male patient visited our hospital for the treatment of herpes zoster, his computed tomography (CT) revealed a mass in his right breast, axillary lymph node enlargement, and multiple lung nodules. A histological examination of the b
Autor:
Mitsuru Yoshimoto, Tohru Takahashi, Michihiro Fujino, Shin-ichi Kanno, Hideto Itoh, Masayuki Tsujisaki
Publikováno v:
Internal Medicine. 53:2121-2125
Plasma cell leukemia (PCL) is a rare variant of multiple myeloma (MM) with a poor prognosis. Nonsecretory myeloma is also a rare form of MM characterized by the absence of detectable M-protein in the serum and urine. This report describes two cases o
Autor:
Akihide Ito, Michihiro Fujino, Akira Isada, K. Ito, Atsuo Hattori, Fujiya Kishi, Yasushi Akiyama
Publikováno v:
Internal Medicine. 45:819-822
A 48-year-old man with dyspnea, cough, and fever was found to have a diffuse ground-glass pulmonary lesion without lymphadenopathy on chest X-ray. The lesion shifted to the peripheral lung zones 2 months later when transbronchial biopsy demonstrated
Autor:
Yasushi, Akiyama, Junko, Kato, Kenichiro, Itoh, Chihnatsu, Moriyama, Michihiro, Fujino, Masashi, Ohe, Fujiya, Kishi
Publikováno v:
北海道社会保険病院紀要 = Proceedings of Hokkaido Social Insurance Hospital. 5:8-10
A53-year-01d woman who was hypoxemic due to primary lung adenocarcinoma with both pleuritis and pericarditis carcinomatosa was treated with gefitinib,an inhibitor of the epithelial growth factor receptor (EGFR) tyrosine kinase.The tumor seemed to p
Autor:
Shi-Xue Hu, Ichiro Kinoshita, Hong-Ji Xu, Yoshikazu Kawakami, Hirotoshi Dosaka-Akita, Noboru Kuzumaki, Michihiro Fujino, William F. Benedict, Masao Harada
Publikováno v:
Cancer. 79:1329-1337
BACKGROUND Inactivation of the retinoblastoma (Rb) gene has been documented in various types of cancer, including lung cancer. Alterations of the p53 and ras genes are also common features in the molecular biology of lung carcinoma, and the authors o
Autor:
Kenji Akie, Michihiro Fujino, Yoshikazu Kawakami, Hirotoshi Dosaka-Akita, Ichiro Kinoshita, Hiromitsu Hiroumi, Masao Harada
Publikováno v:
Cancer. 76:2457-2463
Background. Alterations of the p53 gene are one of the most common genetic changes in various types of cancer, including lung cancer. Abnormalities in the ras genes, including point mutations and overexpression, are another common feature in the mole
Autor:
M. Katoh, Ichiro Kinoshita, Masanobu Shindoh, Kenji Akie, Hirotoshi Dosaka-Akita, Michihiro Fujino, Yoshikazu Kawakami
Publikováno v:
American Journal of Clinical Pathology. 102:660-664
Among the most common mutations in human lung cancer are those affecting the p53 gene. The expression of p53 in the nucleus is considered an immunohistochemical reflection of the nuclear accumulation of mutant p53 protein, which is coded by the p53 g
Autor:
Masaki Togashi, Satoshi Nagamori, Hirotoshi Akita, Hiroshi Isobe, Hiroshi Miyamato, Michihiro Fujino, Takashi Endo, Yoshikazu Kawakami, Shosaku Abe, Kazuaki Inoue
Publikováno v:
The Journal of the Japanese Society of Clinical Cytology. 31:426-430
Autor:
Michihiro Fujino, Masao Harada, Masakazu Kato, Hiroshi Miyamoto, Yoshikazu Kawakami, Hirotoshi Akita, Hitoshi Haneda, Hiroshi Isobe, Kenji Okayasu, Akihiko Ishiguro
Publikováno v:
Haigan. 32:177-184
切除肺癌の核DNA量を測定し, また, ras癌遺伝子産物p21蛋白の発現を免疫組織化学的に調べ, それらの肺癌患者の予後における意義を検討した.DNA量を測定した84腫瘍のうち, 19例 (23%) がDNA dipl