Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Michihiro, Mieda"'
Autor:
Yusuke Tsuno, Michihiro Mieda
Publikováno v:
Frontiers in Neural Circuits, Vol 18 (2024)
Animals need sleep, and the suprachiasmatic nucleus, the center of the circadian rhythm, plays an important role in determining the timing of sleep. The main input to the suprachiasmatic nucleus is the retinohypothalamic tract, with additional inputs
Externí odkaz:
https://doaj.org/article/89fd5acd015c4fb38922b97111938fd4
Autor:
Kaito Onodera, Yusuke Tsuno, Yuichi Hiraoka, Kohichi Tanaka, Takashi Maejima, Michihiro Mieda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Prokineticin 2 (Prok2) is a small protein expressed in a subpopulation of neurons in the suprachiasmatic nucleus (SCN), the primary circadian pacemaker in mammals. Prok2 has been implicated as a candidate output molecule from the SCN to cont
Externí odkaz:
https://doaj.org/article/83436af8438343a89643f5071b6f2bfb
Autor:
Yusuke Tsuno, Yubo Peng, Shin-Ichi Horike, Mohan Wang, Ayako Matsui, Kanato Yamagata, Mizuki Sugiyama, Takahiro J Nakamura, Takiko Daikoku, Takashi Maejima, Michihiro Mieda
Publikováno v:
PLoS Biology, Vol 21, Iss 8, p e3002281 (2023)
The central circadian clock of the suprachiasmatic nucleus (SCN) is a network consisting of various types of neurons and glial cells. Individual cells have the autonomous molecular machinery of a cellular clock, but their intrinsic periods vary consi
Externí odkaz:
https://doaj.org/article/396143e499fe43d793ad3239192df9bc
Autor:
Gyujin Park, Kazuya Fukasawa, Tetsuhiro Horie, Yusuke Masuo, Yuka Inaba, Takanori Tatsuno, Takanori Yamada, Kazuya Tokumura, Sayuki Iwahashi, Takashi Iezaki, Katsuyuki Kaneda, Yukio Kato, Yasuhito Ishigaki, Michihiro Mieda, Tomohiro Tanaka, Kazuma Ogawa, Hiroki Ochi, Shingo Sato, Yun-Bo Shi, Hiroshi Inoue, Hojoon Lee, Eiichi Hinoi
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Hypothalamic neurons regulate body homeostasis by sensing and integrating changes in the levels of key hormones and primary nutrients (amino acids, glucose, and lipids). However, the molecular mechanisms that enable hypothalamic neurons to detect pri
Externí odkaz:
https://doaj.org/article/69274c6ccd734fd68d05813f708b0c90
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-14 (2022)
Abstract Self-grooming plays an essential role in hygiene maintenance, thermoregulation, and stress response. However, the neural populations involved in self-grooming remain largely unknown. The paraventricular hypothalamic nucleus (PVH) has been im
Externí odkaz:
https://doaj.org/article/a2ea85baf3324f4eadae8dbeb68eba73
Autor:
Jureepon Roboon, Tsuyoshi Hattori, Dinh Thi Nguyen, Hiroshi Ishii, Mika Takarada-Iemata, Takayuki Kannon, Kazuyoshi Hosomichi, Takashi Maejima, Kengo Saito, Yohei Shinmyo, Michihiro Mieda, Atsushi Tajima, Hiroshi Kawasaki, Osamu Hori
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Astrocytes play key roles in supporting the central nervous system structure, regulating synaptic functions, and maintaining brain homeostasis. The number of astrocytes in the cerebrum has markedly increased through evolution. However, the manner by
Externí odkaz:
https://doaj.org/article/98c41baf133c4cf499d47aa1978fad2d
Autor:
Karen J. Tonsfeldt, Laura J. Cui, Jinkwon Lee, Thijs J. Walbeek, Liza E. Brusman, Ye Jin, Michihiro Mieda, Michael R. Gorman, Pamela L. Mellon
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Disruptions to the circadian system alter reproductive capacity, particularly in females. Mice lacking the core circadian clock gene, Bmal1, are infertile and have evidence of neuroendocrine disruption including the absence of the preovulatory lutein
Externí odkaz:
https://doaj.org/article/ccc8699a188a4143890678faf2da2f60
Autor:
Yubo Peng, Yusuke Tsuno, Ayako Matsui, Yuichi Hiraoka, Kohichi Tanaka, Shin-ichi Horike, Takiko Daikoku, Michihiro Mieda
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The suprachiasmatic nucleus (SCN), the central circadian clock in mammals, is a neural network consisting of various types of GABAergic neurons, which can be differentiated by the co-expression of specific peptides such as vasoactive intestinal pepti
Externí odkaz:
https://doaj.org/article/227bbdf86a8346c6ae31893eb59452a7
Autor:
Nazmul Hasan, Naoto Nagata, Jun-ichi Morishige, Md Tarikul Islam, Zheng Jing, Ken-ichi Harada, Michihiro Mieda, Masanori Ono, Hiroshi Fujiwara, Takiko Daikoku, Tomoko Fujiwara, Yoshiko Maida, Tsuguhito Ota, Shigeki Shimba, Shuichi Kaneko, Akio Fujimura, Hitoshi Ando
Publikováno v:
Molecular Metabolism, Vol 49, Iss , Pp 101202- (2021)
Objective: Impaired circadian clocks can cause obesity, but their pathophysiological role in brown adipose tissue (BAT), a major tissue regulating energy metabolism, remains unclear. To address this issue, we investigated the effects of complete disr
Externí odkaz:
https://doaj.org/article/4ef08ae78982402b94b53810ee3af358
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