Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Michihiko Sugimoto"'
Autor:
Masaki Yagi, Mio Kabata, Tomoyo Ukai, Sho Ohta, Akito Tanaka, Yui Shimada, Michihiko Sugimoto, Kimi Araki, Keisuke Okita, Knut Woltjen, Konrad Hochedlinger, Takuya Yamamoto, Yasuhiro Yamada
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 1113-1128 (2019)
Summary: CpG islands (CGIs) including those at imprinting control regions (ICRs) are protected from de novo methylation in somatic cells. However, many cancers often exhibit CGI hypermethylation, implying that the machinery is impaired in cancer cell
Externí odkaz:
https://doaj.org/article/16df7a08bde34afb9cf8bc2e9b4162c2
Autor:
Kazumasa Takemoto, Naoki Tani, Yuki Takada-Horisawa, Sayoko Fujimura, Nobuhiro Tanno, Mariko Yamane, Kaho Okamura, Michihiko Sugimoto, Kimi Araki, Kei-ichiro Ishiguro
Publikováno v:
Cell Reports, Vol 31, Iss 8, Pp - (2020)
Summary: Meiotic recombination is critical for genetic exchange and generation of chiasmata that ensures faithful chromosome segregation during meiosis I. Meiotic recombination is initiated by DNA double-strand break (DSB) followed by multiple proces
Externí odkaz:
https://doaj.org/article/0d8530f0fc044b2790b7d99713c75123
Autor:
Michihiko Sugimoto, Masayo Kondo, Yumiko Koga, Hirosuke Shiura, Rieko Ikeda, Michiko Hirose, Atsuo Ogura, Ayumi Murakami, Atsushi Yoshiki, Susana M. Chuva de Sousa Lopes, Kuniya Abe
Publikováno v:
Stem Cell Reports, Vol 4, Iss 4, Pp 744-757 (2015)
Epiblast stem cells (EpiSCs) are pluripotent stem cells derived from epiblasts of postimplantation mouse embryos, and thus provide a useful model for studying “primed” pluripotent states. Here, we devised a simple and robust technique to derive h
Externí odkaz:
https://doaj.org/article/6e8920f1c6a44f28beed974f08200b37
Autor:
Michihiko Sugimoto, Masayo Kondo, Michiko Hirose, Misao Suzuki, Kazuyuki Mekada, Takaya Abe, Hiroshi Kiyonari, Atsuo Ogura, Nobuo Takagi, Karen Artzt, Kuniya Abe
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1363-1374 (2012)
After implantation, pluripotent epiblasts are converted to embryonic ectoderm through cell–cell interactions that significantly change the transcriptional and epigenetic networks. An entrée to understanding this vital developmental transition is t
Externí odkaz:
https://doaj.org/article/cf438d14233442aaa53f540eb035b9bc
Autor:
Liqin Cao, Hiroshi Shitara, Michihiko Sugimoto, Jun-Ichi Hayashi, Kuniya Abe, Hiromichi Yonekawa
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000756 (2009)
In mammals, observations of rapid shifts in mitochondrial DNA (mtDNA) variants between generations have led to the creation of the bottleneck theory for the transmission of mtDNA. The bottleneck could be attributed to a marked decline of mtDNA conten
Externí odkaz:
https://doaj.org/article/90c0f44f1d2d4cbabc8776958be3d3fa
Autor:
Michihiko Sugimoto, Kuniya Abe
Publikováno v:
PLoS Genetics, Vol 3, Iss 7, p e116 (2007)
During primordial germ cell (PGC) development, epigenetic reprogramming events represented by X chromosome reactivation and erasure of genomic imprinting are known to occur. Although precise timing is not given, X reactivation is thought to take plac
Externí odkaz:
https://doaj.org/article/d7060d92298443338d11ffb4ccbdda4d
Autor:
Takashi Kamatani, Hiroki Hagizawa, Seido Yarimitsu, Miho Morioka, Saeko Koyamatsu, Michihiko Sugimoto, Joe Kodama, Junko Yamane, Hiroyuki Ishiguro, Shigeyuki Shichino, Kuniya Abe, Wataru Fujibuchi, Hiromichi Fujie, Takashi Kaito, Noriyuki Tsumaki
Publikováno v:
Biomaterials. 284
The loss of nucleus pulposus (NP) precedes the intervertebral disk (IVD) degeneration that causes back pain. Here, we demonstrate that the implantation of human iPS cell-derived cartilaginous tissue (hiPS-Cart) restores this loss by replacing lost NP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47471dcb7b0ca19f3345209cb96ea76c
http://hdl.handle.net/2433/269454
http://hdl.handle.net/2433/269454
Publikováno v:
Genes to cells : devoted to molecularcellular mechanismsREFERENCES. 27(1)
LincRNA-p21 is a long intergenic non-coding RNA (LincRNA) gene reported to activate the transcription of the adjacent Cdkn1a (p21) gene in cis. The importance of the enhancer elements in the LincRNA-p21 gene region has also been reported; however, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc309d1761bf0eb94ed2692883373b8
https://pubmed.ncbi.nlm.nih.gov/34808017
https://pubmed.ncbi.nlm.nih.gov/34808017
Autor:
Akito Tanaka, Yui Shimada, Sho Ohta, Michihiko Sugimoto, Keisuke Okita, Yasuhiro Yamada, Mio Kabata, Konrad Hochedlinger, Tomoyo Ukai, Takuya Yamamoto, Masaki Yagi, Kimi Araki, Knut Woltjen
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 1113-1128 (2019)
CpG islands (CGIs) including those at imprinting control regions (ICRs) are protected from de novo methylation in somatic cells. However, many cancers often exhibit CGI hypermethylation, implying that the machinery is impaired in cancer cells. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179a3024e2fd3431d35668ac10a66a3d
http://www.sciencedirect.com/science/article/pii/S2213671119301304
http://www.sciencedirect.com/science/article/pii/S2213671119301304
Autor:
Michihiko Sugimoto, Sayoko Fujimura, Nobuhiro Tanno, Kei-ichiro Ishiguro, Naoki Tani, Kaho Okamura, Mariko Yamane, Kazumasa Takemoto, Kimi Araki, Yuki Takada-Horisawa
SummaryMeiotic recombination is critical for genetic exchange and generation of chiasmata that ensures faithful chromosome segregation during meiosis I. Meiotic recombination is initiated by DNA double-strand break (DSB) followed by multiple processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71748ee33f1e7825936aacfa7d7ebb81
https://doi.org/10.1101/2020.02.14.950204
https://doi.org/10.1101/2020.02.14.950204
