Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Michiharu Sakakida"'
Autor:
Eiichi Araki, Akiko Matsuyoshi, Michiharu Sakakida, Takeshi Chirioka, Kayo Taketa, Fumi Sakamoto, Kaku Tsuruzoe, Seiya Shimoda, Nobuhiro Miyamura
Publikováno v:
Diabetes Research and Clinical Practice. 72:238-243
A 75-year-old man with type 1 diabetes and history of insulin therapy for previous 3 years using only human recombinant ones was suffering from unstable glycemic control. He had a high level of total insulin and a high titer of insulin antibodies (IA
Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice
Autor:
Kazuhiko Kume, Kaku Tsuruzoe, Shoen Kume, Junji Kawashima, Hideo Goto, K. Matsumoto, Michiharu Sakakida, Tatsuya Kondo, Eiichi Araki, Shoko Kodama, Tetsushi Toyonaga
Publikováno v:
Biochemical and Biophysical Research Communications. 327(No. 4):1170-1178
Progenitor cells exist in the adult pancreas and transform to endocrine cells in pathological conditions. To address the mechanism of beta cell regeneration, mice were treated with streptozotocin (STZ group) or streptozotocin and exendin-4 (STZ + Ex-
Autor:
Takeshi Matsumura, Tomoko Matsuo, Takahumi Senokuchi, Eiichi Araki, Hideki Kishikawa, Shinsuke Kiritoshi, Takeshi Nishikawa, Nobuhiro Miyamura, Daisuke Kukidome, Michiharu Sakakida, Nakayasu Wake, Takayuki Sasahara, Kazuhiro Sonoda
Publikováno v:
Diabetes Care. 26:1507-1512
OBJECTIVE—To evaluate urinary 8-hydroxydeoxyguanosine (8-OHdG) as a marker for the progression of diabetic macroangiopathic complications. RESEARCH DESIGN AND METHODS—The content of urinary 8-OHdG, common carotid intima-media thickness (IMT), the
Autor:
Tetsuya Taguchi, Shinsuke Iwashita, Michiharu Sakakida, Kayo Taketa, Tetsushi Toyonaga, Takeshi Nishikawa, Eiichi Araki, Yusuke Murata, Kazuya Matsumoto, Nobuhiro Miyamura
Publikováno v:
Endocrine. 19:319-326
ACTH-independent macronodular adrenal hyperplasia (AIMAH) is a rare disorder and an unusual cause of Cushing s syndrome, of which familial transmission has rarely been reported. In this study, a mother and her son, the former affected with definite A
Autor:
Kazuhiko Ishihara, Seiya Shimoda, Kenshi Ichinose, Tanja Nowak, Kenro Nishida, Michiharu Sakakida, Nobuo Nakabayashi, Motoaki Shichiri, Y. Konno
Publikováno v:
Journal of Artificial Organs. 3:39-46
Biocompatibility is important to assure a mild body reaction to an implanted device and its long-term stability and functionality. In diabetes research, subcutaneously implanted glucose monitoring systems need biocompatible surfaces for long-term app
Publikováno v:
Artificial Organs. 22:32-42
At present, 2 major problems should be solved before long-term application of the wearable artificial endocrine pancreas, the development of a reliable and stable glucose monitoring system and the development of a subcutaneous insulin infusion algori
Autor:
Mihoko Kodama, Norio Niikawa, Takako Otsuka, Noritaka Iwatani, Teruhisa Miike, Motoaki Shichiri, Yoshihiro Jinno, Michiharu Sakakida
Publikováno v:
Japanese Journal of Human Genetics. 42:323-329
Deletions and point mutations of the growth hormone (GH) receptor gene (GHR) have been identified in patients with Laron syndrome. We report the first detection of the GHR mutation among Japanese patients with Laron syndrome. Using the Japanese femal
Autor:
Noritaka Iwatani, Motoaki Shichiri, Takako Otsuka, Teruhisa Miike, Michiharu Sakakida, Hiroyo Mabe, Yoshihiro Jinno, Mihoko Kodama, Norio Niikawa
Publikováno v:
Folia Endocrinologica Japonica. 73:643-649
Publikováno v:
Diabetes Care. 17:387-396
OBJECTIVE To develop a reliable and practical glucose monitoring system by combining a needle-type glucose sensor with a microdialysis sampling technique for long-term subcutaneous tissue glucose measurements. RESEARCH DESIGN AND METHODS A microdialy
Publikováno v:
Sensors and Actuators B: Chemical. 13:319-322
A ferrocene-mediated needle-type glucose sensor covered with a newly designed biocompatible membrane of 2-methacryloyloxyethyl phosphorylcholine (MPC) has been developed and its characteristics examined in vitro and in vivo. Application of ferrocene