Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michiel W. van den Heuvel"'
Publikováno v:
British Journal of Clinical Pharmacology. 72:415-433
AIMS An integrated population pharmacokinetic–pharmacodynamic model was developed with the following aims: to simultaneously describe pharmacokinetic behaviour of sugammadex and rocuronium; to establish the pharmacokinetic–pharmacodynamic model f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05264b35132bc0e2a616d52d07bac84f
https://doi.org/10.1111/j.1365-2125.2011.04000.x
https://doi.org/10.1111/j.1365-2125.2011.04000.x
Autor:
Ryan C. Vargo, Filippos Kesisoglou, Stefaan Rossenu, Colm Farrell, Marita Prohn, Shaun Fitzpatrick, Pieter-Jan de Kam, Michiel W. van den Heuvel
Publikováno v:
Journal of pharmaceutical sciences. 103(11)
Development of in vitro – in vivo correlations (IVIVCs) for extended‐release (ER) products is commonly pursued during pharmaceutical development to increase product understanding, set release specifications, and support biowaivers. This manuscrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5461a1689f0f4a62e5db44b8fab30c
https://pubmed.ncbi.nlm.nih.gov/25256703
https://pubmed.ncbi.nlm.nih.gov/25256703
Autor:
Marjan L. F. Jagt-Smook, Steven Ramael, Justin Dennie, Pierre A. M. Peeters, Michiel W. van den Heuvel, Pieter-Jan de Kam, Rob J. W. Berg, Guy Cammu, Peter Grobara
Publikováno v:
Clinical drug investigation. 33(8)
We evaluated the potential for QT/corrected QT (QTc) interval prolongation after sugammadex given with propofol or sevoflurane anaesthesia. This was a two-factorial, randomized, parallel-group study in 132 healthy subjects. Anaesthesia was maintained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab886695592a9718b3c683dbe2404cb
https://pubmed.ncbi.nlm.nih.gov/23824662
https://pubmed.ncbi.nlm.nih.gov/23824662
Autor:
Peter G. Schnabel, Gabriele S. Merki-Feld, Ingrid Duijkers, Ellen Mommers, Alice Malvy, Michiel W. van den Heuvel
The etonogestrel (ENG)-releasing implant is a subdermal progestogen-only contraceptive that provides coverage for up to 3 years. This long-acting hormonal contraceptive has been available in Europe since 1998 and in the US since 2006. To date, locali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf5c21bcabd787b00041c497794be0d
https://www.zora.uzh.ch/id/eprint/71899/
https://www.zora.uzh.ch/id/eprint/71899/
Autor:
Steven Ramael, Alex Zwiers, Pieter-Jan de Kam, Jean-Luc Jadoul, Pierre A.M. Peeters, Michiel W. van den Heuvel, Erik de Clerck, Peter Grobara
Publikováno v:
Clinical drug investigation. 32(3)
Background: Sugammadex, a modified γ-cyclodextrin, facilitates rapid reversal of rocuronium- and vecuronium-induced neuromuscular blockade (NMB). Cyclodextrins are known for their ability to form inclusion complexes with various drugs. Theoretically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341cdec2463d209b94ce7bd0db147a6d
https://pubmed.ncbi.nlm.nih.gov/22201295
https://pubmed.ncbi.nlm.nih.gov/22201295
Publikováno v:
British journal of clinical pharmacology. 72(3)
An integrated population pharmacokinetic-pharmacodynamic model was developed with the following aims: to simultaneously describe pharmacokinetic behaviour of sugammadex and rocuronium; to establish the pharmacokinetic-pharmacodynamic model for rocuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa7980d19f91cba73b117ae116113cc3
https://pubmed.ncbi.nlm.nih.gov/21535448
https://pubmed.ncbi.nlm.nih.gov/21535448
Autor:
Michiel W. van den Heuvel, Pierre A. M. Peeters, Alex Zwiers, Thijs van Iersel, Paul C. C. M. Passier, Emiel van Heumen, Jean Smeets
Publikováno v:
Clinical drug investigation. 30(12)
Sugammadex facilitates rapid reversal of rocuronium- and vecuronium-induced neuromuscular blockade. This study aimed to evaluate the safety, tolerability and pharmacokinetics of high doses of sugammadex (up to 96 mg/kg) in healthy subjects.In this ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f87f8b03f2c05a45653e95cc05ddd1f
https://pubmed.ncbi.nlm.nih.gov/20825252
https://pubmed.ncbi.nlm.nih.gov/20825252
Autor:
Alex Zwiers, Emiel van Heumen, Paul C. C. M. Passier, Jean Smeets, Thijs van Iersel, Michiel W. van den Heuvel, Pierre A. M. Peeters
Publikováno v:
Clinical Drug Investigation. :1
Background and objective Sugammadex facilitates rapid reversal of rocuronium- and vecuronium-induced neuromuscular blockade. This study aimed to evaluate the safety, tolerability and pharmacokinetics of high doses of sugammadex (up to 96 mg/kg) in he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb1dc72f27ef6e3927ec8f6c3e4fda49
https://doi.org/10.2165/11538920-000000000-00000
https://doi.org/10.2165/11538920-000000000-00000