Mapping the EORTC QLQ-C30 and QLQ-H&N35 to the EQ-5D for head and neck cancer: Can disease-specific utilities be obtained?

Autor: Ann-Jean C C Beck, Jacobien M Kieffer, Valesca P Retèl, Lydia F J van Overveld, Robert P Takes, Michiel W M van den Brekel, Wim H van Harten, Martijn M Stuiver

Publikováno v: PLoS ONE, Vol 14, Iss 12, p e0226077 (2019)

INTRODUCTION:Innovations in head and neck cancer (HNC) treatment are often subject to economic evaluation prior to their reimbursement and subsequent access for patients. Mapping functions facilitate economic evaluation of new treatments when the req

Externí odkaz: https://doaj.org/article/ba9466165a874f7cb8ec5e9d2f77ab0f

Role of variant allele fraction and rare SNP filtering to improve cellular DNA repair endpoint association.

Autor: David M Vossen, Caroline V M Verhagen, Reidar Grénman, Roelof J C Kluin, Marcel Verheij, Michiel W M van den Brekel, Lodewyk F A Wessels, Conchita Vens

Publikováno v: PLoS ONE, Vol 13, Iss 11, p e0206632 (2018)

BACKGROUND:Large cancer genome studies continue to reveal new players in treatment response and tumorigenesis. The discrimination of functional alterations from the abundance of passenger genetic alterations still poses challenges and determines DNA

Externí odkaz: https://doaj.org/article/1ece493379cf446194cdc3f9516511b8

Understanding and predicting the performance of passive heat and moisture exchangers using a numerical model

Autor: Maartje Leemans, Maarten J. A. van Alphen, Wim Vallenduuk, Richard Dirven, Michiel W. M. van den Brekel, Sara H. Muller

Publikováno v: Head and Neck, 45(4), 993-1005. John Wiley and Sons Inc.

Background: To improve the understanding of the thermodynamics and performance of small passive hygroscopic Heat and Moisture Exchangers (HMEs), a computer model simulating HME function is required. Methods: We developed a numerical HME model to calc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0171f70e1a2a348f541a3f155c8c8ef8
https://doi.org/10.1002/hed.27314

Biological Determinants of Chemo-Radiotherapy Response in HPV-Negative Head and Neck Cancer: A Multicentric External Validation

Autor: Martijn van der Heijden, Paul B. M. Essers, Monique C. de Jong, Reinout H. de Roest, Sebastian Sanduleanu, Caroline V. M. Verhagen, Olga Hamming-Vrieze, Frank Hoebers, Philippe Lambin, Harry Bartelink, C. René Leemans, Marcel Verheij, Ruud H. Brakenhoff, Michiel W. M. van den Brekel, Conchita Vens

Publikováno v: Frontiers in Oncology, Vol 9 (2020)

Purpose: Tumor markers that are related to hypoxia, proliferation, DNA damage repair and stem cell-ness, have a prognostic value in advanced stage HNSCC patients when assessed individually. Here we aimed to evaluate and validate this in a multifactor

Externí odkaz: https://doaj.org/article/3b05fb098e53417c96657e4cfa21c600

Dysphagia, trismus and speech impairment following radiation-based treatment for advanced stage oropharyngeal carcinoma: a one-year prospective evaluation

Autor: Remco de Bree, Rob J.J.H. van Son, Lisette van der Molen, Najiba Chargi, Frans J. M. Hilgers, Jan de Boer, Martijn M. Stuiver, Rebecca T. Karsten, Ludi E. Smeele, Abrahim Al-Mamgani, Michiel W. M. van den Brekel

Publikováno v: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS). Springer Verlag
European Archives of Oto-Rhino-Laryngology and Head & Neck, 279, 1003-1027. Springer Nature Switzerland AG
Karsten, R T, Chargi, N, van der Molen, L, van Son, R J J H, de Bree, R, Al-Mamgani, A, de Boer, J P, Hilgers, F J M, van den Brekel, M W M, Smeele, L E & Stuiver, M M 2022, ' Dysphagia, trismus and speech impairment following radiation-based treatment for advanced stage oropharyngeal carcinoma: a one-year prospective evaluation ', European Archives of Oto-Rhino-Laryngology, vol. 279, no. 2, pp. 1003-1027 . https://doi.org/10.1007/s00405-021-06870-x
European Archives of Oto-Rhino-Laryngology, 279(2). Springer Verlag
European Archives of Oto-Rhino-Laryngology, 279(2), 1003-1027. Springer Verlag
Karsten, R T, Chargi, N, van der Molen, L, van Son, R J J H, de Bree, R, Al-Mamgani, A, de Boer, J P, Hilgers, F J M, van den Brekel, M W M, Smeele, L E & Stuiver, M M 2022, ' Dysphagia, trismus and speech impairment following radiation-based treatment for advanced stage oropharyngeal carcinoma : a one-year prospective evaluation ', European Archives of Oto-Rhino-Laryngology, vol. 279, no. 2, pp. 1003-1027 . https://doi.org/10.1007/s00405-021-06870-x

Objective: The objective was to assess swallowing, mouth opening and speech function during the first year after radiation-based treatment (RT(+)) after introduction of a dedicated preventive rehabilitation program for stage III–IV oropharyngeal ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba2c6d1f83fe267405d24ae8f463ad8
https://doi.org/10.1007/s00405-021-06870-x