Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michiel J M Niesen"'
Autor:
Robert P Matson, BS, Michiel J M Niesen, PhD, Emily R Levy, MD, Derek N Opp, DO, Patrick J Lenehan, PhD, Greg Donadio, MA, John C O'Horo, ProfMD, A J Venkatakrishnan, PhD, Andrew D Badley, ProfMD, Venky Soundararajan, PhD
Publikováno v:
The Lancet: Digital Health, Vol 5, Iss 4, Pp e206-e216 (2023)
Summary: Background: The emergency use authorisation of BNT162b2 (tozinameran; Comirnaty, Pfizer–BioNTech) for children aged 5–17 years has resulted in rapid vaccination in the paediatric population. However, there are few studies of adverse even
Externí odkaz:
https://doaj.org/article/7a5fc9eade034d6dad7d93a8c05949a9
Autor:
Rohit Suratekar, Pritha Ghosh, Michiel J M Niesen, Gregory Donadio, Praveen Anand, Venky Soundararajan, A J Venkatakrishnan
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 2, Pp 1-10 (2022)
Abstract The highly contagious Delta variant of SARS‐CoV‐2 has become a prevalent strain globally and poses a public health challenge around the world. While there has been extensive focus on understanding the amino acid mutations in the Delta va
Externí odkaz:
https://doaj.org/article/2cc1e88e04c54521bcb418b729fd04e2
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 3, p e1005427 (2017)
We present a coarse-grained simulation model that is capable of simulating the minute-timescale dynamics of protein translocation and membrane integration via the Sec translocon, while retaining sufficient chemical and structural detail to capture ma
Externí odkaz:
https://doaj.org/article/7da32171d5524cd2834cd436261ca3af
Autor:
Michiel J M Niesen, Robert Matson, Arjun Puranik, John C O'Horo, Colin Pawlowski, Celine Vachon, Douglas Challener, Abinash Virk, Melanie Swift, Leigh Speicher, Joel Gordon, Holly Geyer, Patrick J Lenehan, A J Venkatakrishnan, Venky Soundararajan, Andrew Badley
Publikováno v:
PNAS Nexus. 1
As of 2021 November 29, booster vaccination against SARS-CoV-2 infection has been recommended for all individuals aged 18 years and older in the United States. A key reason for this recommendation is the expectation that a booster vaccine dose can al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0119faf48d3c757579f2110da83fb7a0
https://doi.org/10.1093/pnasnexus/pgac042
https://doi.org/10.1093/pnasnexus/pgac042
Autor:
Arjun Puranik, Patrick J Lenehan, John C O'Horo, Colin Pawlowski, Michiel J M Niesen, Abinash Virk, Melanie D Swift, Walter Kremers, A J Venkatakrishnan, Joel E Gordon, Holly L Geyer, Leigh Lewis Speicher, Venky Soundararajan, Andrew D Badley
Publikováno v:
PNAS nexus. 1(3)
COVID-19 vaccines are effective, but breakthrough infections have been increasingly reported. We conducted a test-negative case-control study to assess the durability of protection after full vaccination with BNT162b2 against polymerase chain reactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4cf270a2e5de734e6f4fd5e7b25eb2
https://pubmed.ncbi.nlm.nih.gov/35832867
https://pubmed.ncbi.nlm.nih.gov/35832867
Autor:
A. J. Venkatakrishnan, Praveen Anand, Patrick J. Lenehan, Rohit Suratekar, Bharathwaj Raghunathan, Michiel J. M. Niesen, Venky Soundararajan
Publikováno v:
Vaccines. 10:1509
The emergence of a heavily mutated SARS-CoV-2 variant (Omicron; Pango lineage B.1.1.529 and BA sublineages) and its rapid spread to over 75 countries raised a global public health alarm. Characterizing the mutational profile of Omicron is necessary t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a139a1ed911f96855f8549b2fb6507a3
https://doi.org/10.3390/vaccines10091509
https://doi.org/10.3390/vaccines10091509
Autor:
Michiel J. M. Niesen, Colin Pawlowski, John C. O’Horo, Doug W. Challener, Eli Silvert, Greg Donadio, Patrick J. Lenehan, Abinash Virk, Melanie D. Swift, Leigh L. Speicher, Joel E. Gordon, Holly L. Geyer, John D. Halamka, A. J. Venkatakrishnan, Venky Soundararajan, Andrew D. Badley
Publikováno v:
JAMA Network Open. 5:e227038
Recent reports on waning of COVID-19 vaccine-induced immunity have led to the approval and rollout of additional doses and booster vaccinations. Individuals at increased risk of SARS-CoV-2 infection are receiving additional vaccine doses in addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b350d4d6a5a86eb88a136341eb4c527
https://doi.org/10.1001/jamanetworkopen.2022.7038
https://doi.org/10.1001/jamanetworkopen.2022.7038
Autor:
Martin D. Gelenter, Venkata S. Mandala, Michiel J. M. Niesen, Dina A. Sharon, Aurelio J. Dregni, Adam P. Willard, Mei Hong
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
To understand how water in the channel made of the influenza B M2 protein mediates proton transport across the lipid membrane, Gelenter et al. investigate the water orientation and dynamics. This study suggests that faster dynamics and higher orienta
Externí odkaz:
https://doaj.org/article/589f0e86237b4a8cafe159e50811cbe3