Výsledky vyhledávání - "Michiari Okuda"

Mitochondrial Dysfunction in Hepatitis C

Autor: Kazuhiro Otani, Steven A. Weinman, Masaaki Korenaga, Yanchun Li, Michiari Okuda, Ting Wang

Publikováno v: Journal of Clinical Gastroenterology. 39:S162-S166

Chronic hepatitis C induces a state of hepatic oxidative stress that is more pronounced than that present in many other inflammatory liver diseases. This review summarizes recent information that the hepatitis C virus (HCV) core protein plays an impo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342713149802420eac9d12f730b11c78
https://doi.org/10.1097/01.mcg.0000155517.02468.46

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Type I interferon receptor and response to interferon therapy in chronic hepatitis C patients: a prospective study

Autor: Y. Kubo, K. Uchida, D. Fujiwara, Michiari Okuda, H. Nakamura, Tomomi Konishi, Masaaki Korenaga, S. Yamashita, Yuhki Yamaguchi, Keisuke Hino, Kiwamu Okita

Publikováno v: Journal of Viral Hepatitis. 11:136-140

Summary. The type I interferon (IFN) receptor consists of at least two subunits, IFNAR1 and IFNAR2. We previously found a correlation between IFNAR1 and IFNAR2 expression in liver, and a correlation in IFNAR2 expression, but not in IFNAR1, between li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9efbd5bbf915d9924caa28aa255b30a
https://doi.org/10.1046/j.1365-2893.2003.00477.x

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Clinical evaluation of chronic liver diseases induced by different hepatitis C virus genotype in Japan, focused on the difference between genotypes III/2a and IV/2b

Autor: Kaori Fujii, Chisa Murakami, Fumio Tsuda, Kiwamu Okita, Masaaki Korenaga, Muneko Okazaki, Makoto Mayumi, Keisuke Hino, Michiari Okuda, Hiroaki Okamoto

Publikováno v: Hepatology Research. 14:204-211

It remains controversial if hepatitis C virus (HCV) genotypes in the same genetic group or type are different in the activity of viral replication and capacity to induce severe clinical disease. HCV genotypes and HCV RNA titers were determined in con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::545196e95ca31622445faaff77bcd761
https://doi.org/10.1016/s1386-6346(99)00002-9

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Risk factors for hepatocellular carcinoma and its incidence after interferon treatment in patients with chronic hepatitis C

Autor: Akinori Kasahara, Shinichi Kakumu, Kiwamu Okita, Akihiro Iijima, Akihiko Urushihara, Michiari Okuda, Norio Hayashi, Kentaro Yoshioka, Kendo Kiyosawa, Keisuke Hino, Kiyoshi Mochizuki, Masahide Takayanagi

Publikováno v: Hepatology. 27:1394-1402

To elucidate the risk factors for liver carcinogenesis and to examine the incidence of hepatocellular carcinoma (HCC) after interferon therapy, 1,022 chronic hepatitis C patients treated with interferon were followed by ultrasonography for 13 to 97 m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ead7daba921ddd2768644b186f3d99d
https://doi.org/10.1002/hep.510270529

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[Untitled]

Autor: Masaaki Korenaga, Kaori Fujii, Muneko Okazaki, Chisa Murakami, Keisuke Hino, Michiari Okuda, Kiwamu Okita

Publikováno v: Digestive Diseases and Sciences. 42:2476-2481

Hepatitis C virus (HCV) circulates as particles having differing buoyant densities. Changes in the relative proportions of virus particles of different densities were examined in 19 patients with chronic hepatitis C: 6 without (group A) and 13 with (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5326bba7f73750b38e2b229c8c06b2a9
https://doi.org/10.1023/a:1018800225815

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An autopsy of a case of acute liver failure associated with adult-onset Still's disease

Autor: Mitsuru Yasunaga, Teruaki Kimura, Takahiro Yamasaki, Kiwamu Okita, Michiari Okuda, Shyuji Mizumachi

Publikováno v: Kanzo. 37:176-181

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4b4c7cdb3cc8197d694760002fdab30
https://doi.org/10.2957/kanzo.37.176

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Relationship of serum 2.5 oligoadenylate synthetase activity during interferon therapy to pretreatment levels or genotypes of serum HCV-RNA

Autor: Isao Sakaida, Mitsuru Yasunaga, Keisuke Hino, Kiwamu Okita, Kenji Mori, Kouzou Kayano, Kazuyuki Takenaka, Masafumi Kubota, Aogu Yamashita, Fujio Murakami, Michiari Okuda, Tomomi Konishi

Publikováno v: International Hepatology Communications. 2:358-362

2.5 oligoadenylate synthetase (2.5AS) activity is induced during interferon (IFN) therapy of patients with chronic hepatitis C. It is assumed that the genotype and quantitative level of hepatitis C virus RNA (HCV-RNA) in serum preceding IFN therapy a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59c25b87c382f082966e24992cdd2a77
https://doi.org/10.1016/0928-4346(94)90033-7

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Effects of secretin on bile production in two kinds of cholestatic models by choledocho-caval fistula and bile duct ligation in rats

Autor: Kiwamu Okita, Yohei Fukumoto, Michiari Okuda, Mitsuru Yasunaga, Masaya Ando

Publikováno v: Gastroenterologia Japonica. 27:396-404

Secretin is known to stimulate bile flow from the bile duct epithelium. To investigate the effects of secretin in cholestasis, we studied the response of the bile flow and the excretion of biliary components to secretin using two cholestatic models w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a0a6df0aa71c72f8595fe426312ccc
https://doi.org/10.1007/bf02777760

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