Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Michiari, Okuda"'
Autor:
Yuichi Hara, Yuhki Yamaguchi, Keisuke Hino, Michiari Okuda, Kohki Yutoku, Fenyu Ren, Kiwamu Okita, Takakazu Furutani, Yasuko Murakami, Ayako Nagai, Akira Kitase, Misako Okita, Satoyoshi Yamashita
Publikováno v:
Journal of Gastroenterology and Hepatology. 21:1269-1275
Background: Oxidative damage of the erythrocyte membrane plays an important role in ribavirin-induced anemia. The purpose of the present paper was to assess whether supplementation of α-tocopherol and ascorbic acid (vitamins) causes changes in the e
Autor:
Keisuke Hino, Ayako Nagai, Michiari Okuda, Yasuko Murakami, Takayo Kawakami, Yuh-ichi Hara, Kiwamu Okita, Misako Okita, Akira Kitase
Publikováno v:
Nutrition. 22:114-122
Objective We investigated the effects of vitamin E and C supplementation on the fatty acid composition of mononuclear cells and on the clinical observations in patients who had chronic hepatitis C and received interferon-α-2b (IFN-α-2b) and ribavir
Publikováno v:
Journal of Clinical Gastroenterology. 39:S162-S166
Chronic hepatitis C induces a state of hepatic oxidative stress that is more pronounced than that present in many other inflammatory liver diseases. This review summarizes recent information that the hepatitis C virus (HCV) core protein plays an impo
Autor:
Y. Kubo, K. Uchida, D. Fujiwara, Michiari Okuda, H. Nakamura, Tomomi Konishi, Masaaki Korenaga, S. Yamashita, Yuhki Yamaguchi, Keisuke Hino, Kiwamu Okita
Publikováno v:
Journal of Viral Hepatitis. 11:136-140
Summary. The type I interferon (IFN) receptor consists of at least two subunits, IFNAR1 and IFNAR2. We previously found a correlation between IFNAR1 and IFNAR2 expression in liver, and a correlation in IFNAR2 expression, but not in IFNAR1, between li
Autor:
Kaori Fujii, Chisa Murakami, Fumio Tsuda, Kiwamu Okita, Masaaki Korenaga, Muneko Okazaki, Makoto Mayumi, Keisuke Hino, Michiari Okuda, Hiroaki Okamoto
Publikováno v:
Hepatology Research. 14:204-211
It remains controversial if hepatitis C virus (HCV) genotypes in the same genetic group or type are different in the activity of viral replication and capacity to induce severe clinical disease. HCV genotypes and HCV RNA titers were determined in con
Autor:
Akinori Kasahara, Shinichi Kakumu, Kiwamu Okita, Akihiro Iijima, Akihiko Urushihara, Michiari Okuda, Norio Hayashi, Kentaro Yoshioka, Kendo Kiyosawa, Keisuke Hino, Kiyoshi Mochizuki, Masahide Takayanagi
Publikováno v:
Hepatology. 27:1394-1402
To elucidate the risk factors for liver carcinogenesis and to examine the incidence of hepatocellular carcinoma (HCC) after interferon therapy, 1,022 chronic hepatitis C patients treated with interferon were followed by ultrasonography for 13 to 97 m
Autor:
Masaaki Korenaga, Kaori Fujii, Muneko Okazaki, Chisa Murakami, Keisuke Hino, Michiari Okuda, Kiwamu Okita
Publikováno v:
Digestive Diseases and Sciences. 42:2476-2481
Hepatitis C virus (HCV) circulates as particles having differing buoyant densities. Changes in the relative proportions of virus particles of different densities were examined in 19 patients with chronic hepatitis C: 6 without (group A) and 13 with (
Autor:
Mitsuru Yasunaga, Teruaki Kimura, Takahiro Yamasaki, Kiwamu Okita, Michiari Okuda, Shyuji Mizumachi
Publikováno v:
Kanzo. 37:176-181
Autor:
Isao Sakaida, Mitsuru Yasunaga, Keisuke Hino, Kiwamu Okita, Kenji Mori, Kouzou Kayano, Kazuyuki Takenaka, Masafumi Kubota, Aogu Yamashita, Fujio Murakami, Michiari Okuda, Tomomi Konishi
Publikováno v:
International Hepatology Communications. 2:358-362
2.5 oligoadenylate synthetase (2.5AS) activity is induced during interferon (IFN) therapy of patients with chronic hepatitis C. It is assumed that the genotype and quantitative level of hepatitis C virus RNA (HCV-RNA) in serum preceding IFN therapy a
Publikováno v:
Gastroenterologia Japonica. 27:396-404
Secretin is known to stimulate bile flow from the bile duct epithelium. To investigate the effects of secretin in cholestasis, we studied the response of the bile flow and the excretion of biliary components to secretin using two cholestatic models w