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pro vyhledávání: '"Michely Chen"'
Autor:
Simon Milette, Masakazu Hashimoto, Stephanie Perrino, Shu Qi, Michely Chen, Boram Ham, Ni Wang, Roman Istomine, Andrew M. Lowy, Ciriaco A. Piccirillo, Pnina Brodt
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
It is known that estrogens can affect the immune response to cancer. Here, the authors show that estrogen depletion through ovariectomy reduces the extent of liver metastasis and that this is accompanied by a decrease in the number and function of im
Externí odkaz:
https://doaj.org/article/03601799ff694067bb6f3ab7d58e813f
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 297 (2023)
Pediatric high-grade gliomas (pHGG) accounts for approximately 8–12% of primary brain tumors in children. Prognosis is poor, with a median survival of 9–15 months. Insulin-like growth factor 1-receptor (IGF-1R) gene amplifications have been ident
Externí odkaz:
https://doaj.org/article/f99b3ce56232472e89038a97b3d7ec18
Publikováno v:
Cells, Vol 9, Iss 5, p 1098 (2020)
The insulin-like growth factor (IGF)-axis was implicated in cancer progression and identified as a clinically important therapeutic target. Several IGF-I receptor (IGF-IR) targeting drugs including humanized monoclonal antibodies have advanced to pha
Externí odkaz:
https://doaj.org/article/4b4690c9c9b94c0d8017cd8ccb9e1854
Autor:
Masakazu Hashimoto, Roman Istomine, Stephanie Perrino, Andrew M. Lowy, Pnina Brodt, Michely Chen, Ciriaco A. Piccirillo, Shu Qi, Boram Ham, Simon Milette, Ni Wang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
Liver metastases (LM) remain a major cause of cancer-associated death and a clinical challenge. Here we explore a sexual dimorphism observed in the regulation of the tumor immune microenvironment (TIME) of LM, wherein the accumulation of myeloid-deri
Akademický článek
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