Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Michelle Y-H Lee"'
Autor:
Michelle Y-H Lee, Georges Khoury, Moshe Olshansky, Secondo Sonza, Glen P. Carter, James McMahon, Timothy P. Stinear, Stephen J. Turner, Sharon R. Lewin, Damian F. J. Purcell
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Latent HIV-1 provirus in infected individuals on suppressive therapy does not always remain transcriptionally silent. Both HIV-1 LTR and human gene promoter derived transcriptional events can contribute HIV-1 sequences to the mRNA produced in the cel
Externí odkaz:
https://doaj.org/article/c2f040ad12cf4dec9245f544d8ddf3bf
Autor:
Michelle Y-H Lee, Amit A Upadhyay, Hasse Walum, Chi N Chan, Reem A Dawoud, Christine Grech, Justin L Harper, Kirti A Karunakaran, Sydney A Nelson, Ernestine A Mahar, Kyndal L Goss, Diane G Carnathan, Barbara Cervasi, Kiran Gill, Gregory K Tharp, Elizabeth R Wonderlich, Vijayakumar Velu, Simon M Barratt-Boyes, Mirko Paiardini, Guido Silvestri, Jacob D Estes, Steven E Bosinger
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009674 (2021)
HIV associated immune activation (IA) is associated with increased morbidity in people living with HIV (PLWH) on antiretroviral therapy, and remains a barrier for strategies aimed at reducing the HIV reservoir. The underlying mechanisms of IA have no
Externí odkaz:
https://doaj.org/article/23f45ec77beb4055b59259a74d913d13
Autor:
Amit A. Upadhyay, Elise G. Viox, Timothy N. Hoang, Arun K. Boddapati, Maria Pino, Michelle Y.-H. Lee, Jacqueline Corry, Zachary Strongin, David A. Cowan, Elizabeth N. Beagle, Tristan R. Horton, Sydney Hamilton, Hadj Aoued, Justin L. Harper, Christopher T. Edwards, Kevin Nguyen, Kathryn L. Pellegrini, Gregory K. Tharp, Anne Piantadosi, Rebecca D. Levit, Rama R. Amara, Simon M. Barratt-Boyes, Susan P. Ribeiro, Rafick P. Sekaly, Thomas H. Vanderford, Raymond F. Schinazi, Mirko Paiardini, Steven E. Bosinger
Publikováno v:
Nature Communications. 14
The immunopathological mechanisms driving the development of severe COVID-19 remain poorly defined. Here, we utilize a rhesus macaque model of acute SARS-CoV-2 infection to delineate perturbations in the innate immune system. SARS-CoV-2 initiates a r