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of 4
pro vyhledávání: '"Michelle Waugh"'
Autor:
Robb U. de Iongh, Tracy Ho, Ursula Greferath, Erica L. Fletcher, Andrew I Jobling, Kirstan A. Vessey, Samuel A Mills, Joanna A. Phipps, Michelle Waugh
Publikováno v:
Optometry and Vision Science
Over the recent years, there have been tremendous advances in our understanding of the genetic and environmental factors associated with the development of age-related macular degeneration (AMD). Examination of retinal changes in various animals has
Autor:
Erica L. Fletcher, Lidia Trogrlic, Andrew I Jobling, Kirstan A. Vessey, Ursula Greferath, Joanna A. Phipps, Michelle Waugh, Tracy Ho
Publikováno v:
Investigative ophthalmologyvisual science. 56(2)
PURPOSE: The chemokine Ccl2, or monocyte chemoattractant protein-1 (MCP-1), has previously been identified as playing a potential role in many ocular diseases; however, its role in mice is less clear. We sought to correlate changes in retinal pigment
Publikováno v:
Investigative Opthalmology & Visual Science. 54:3350
PURPOSE: This work investigates a novel, naturally occurring mouse model of achromatopsia. The specific missense mutation within the Gnat2 gene was identified and the subsequent retinal phenotype characterized. METHODS: The Gnat2 sequence was amplifi
Autor:
Michelle Waugh, Andrew I Jobling, Kirstan A. Vessey, Tracy Ho, Erica L. Fletcher, Ursula Greferath, Joanna A. Phipps
Publikováno v:
Investigative Opthalmology & Visual Science. 53:7833
Purpose The chemokine, Ccl2, and the fractalkine receptor, Cx3cr1, have both been implicated in the pathogenesis of age related macular degeneration (AMD), with mice lacking both genes exhibiting features of AMD by 3 months of age. However, recent re