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pro vyhledávání: '"Michelle Visagie"'
Autor:
Mandie Botes, Tamarin Jurgens, Zohreh Riahi, Michelle Visagie, Rustelle Janse van Vuuren, Anna Margaretha Joubert, Iman van den Bout
Publikováno v:
Cancer Cell International, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background 2-Methoxyestradiol (2ME2) is an estradiol metabolite with well documented antiproliferative properties in many cancer cell lines. However, it is rapidly metabolised in vivo which limits its clinical application. Therefore, more st
Externí odkaz:
https://doaj.org/article/0aaf460e1e65438299e76fc51d74ddac
Autor:
Michelle Visagie, Anne Theron, Thandi Mqoco, Warren Vieira, Renaud Prudent, Anne Martinez, Laurence Lafanechère, Annie Joubert
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e71935 (2013)
2-Methoxyestradiol (2ME2) is a naturally occurring estradiol metabolite which possesses antiproliferative, antiangiogenic and antitumor properties. However, due to its limited biological accessibility, synthetic analogues have been synthesized and te
Externí odkaz:
https://doaj.org/article/0d4768f1db5c42ceaeca946fa5dc627b
Publikováno v:
Cells. 11(21)
Papaverine (PPV), a benzylisoquinoline alkaloid, extracted from the Papaverine somniferum plant, is currently in clinical use as a vasodilator. Research has shown that PPV inhibits phosphodiesterase 10A (PDE10A,) resulting in the accumulation of cycl
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4654
Papaverine (PPV) is a benzylisoquinoline alkaloid isolated from Papaver somniferum that exerts antiproliferative activity. However, several questions remain regarding the biochemical pathways affected by PPV in tumourigenic cells. In this study, the
Autor:
Michelle Visagie
Publikováno v:
Science Trends.