Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michelle Toft"'
Autor:
Sampath, Vanitha, Tupa, Dana, Graham, Michelle Toft, Chatila, Talal A., Spergel, Jonathan M., Nadeau, Kari C.
Publikováno v:
In Annals of Allergy, Asthma & Immunology January 2017 118(1):21-27
Autor:
Jessica A. Hamerman, Kerry S. Campbell, Michelle Toft, Minjian Ni, Alexander W. MacFarlane, Clifford A. Lowell
Publikováno v:
Proceedings of the National Academy of Sciences. 109:267-272
Toll-like receptors (TLRs) recognize pathogens and their components, thereby initiating immune responses to infectious organisms. TLR ligation leads to the activation of NF-κB and MAPKs through well-defined pathways, but it has remained unclear how
Autor:
Changiz Geula, Terry K. Means, Michelle Toft, Suzanne E. Hickman, Andrew D. Luster, Joseph El Khoury, Kinya Terada
Publikováno v:
Nature Medicine. 13:432-438
Microglia are the principal immune cells of the brain. In Alzheimer disease, these brain mononuclear phagocytes are recruited from the blood and accumulate in senile plaques. However, the role of microglia in Alzheimer disease has not been resolved.
Autor:
Michelle Toft, Joseph El Khoury, Kinya Terada, Kathryn J. Moore, Mason W. Freeman, Terry K. Means, Josephine H. Leung, Andrew D. Luster
Publikováno v:
The Journal of Experimental Medicine
Accumulation of inflammatory microglia in Alzheimer's senile plaques is a hallmark of the innate response to beta-amyloid fibrils and can initiate and propagate neurodegeneration characteristic of Alzheimer's disease (AD). The molecular mechanism whe
Autor:
Michelle Toft, Suzanne E. Hickman, Changiz Geula, Joseph El Khoury, Terry K. Means, Andrew D. Luster
Publikováno v:
Clinical Immunology. 123:S138