Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michelle Tickner"'
Publikováno v:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 371(1692)
Developmental environments are crucial for shaping our life course. Elements of the early social and biological environments have been consistently associated with reproduction in humans. To date, a strong focus has been on the relationship between e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65165eeaaf282085a1a718d362e8183
https://pubmed.ncbi.nlm.nih.gov/27022073
https://pubmed.ncbi.nlm.nih.gov/27022073
Autor:
Birger Herzog, Rehan Aqil, David L. Selwood, Basil Hartzoulakis, James Nally, Ian Zachary, Rosemary Lynch, Acely Garza-Garcia, Haiyan Jia, Malini Menon, Mark Stewart, Paul C. Driscoll, Snezana Djordjevic, Ashley Jarvis, Katie Ellard, Natalie Winfield, Charles K. Allerston, Chris Chapman, Michelle Tickner, Lili Cheng
Publikováno v:
Journal of Medicinal Chemistry
We report the molecular design and synthesis of EG00229, 2, the first small molecule ligand for the VEGF-A receptor neuropilin 1 (NRP1) and the structural characterization of NRP1-ligand complexes by NMR spectroscopy and X-ray crystallography. Mutage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ba32a699677d39e6300cb06a3fb833
https://doi.org/10.1021/jm901755g
https://doi.org/10.1021/jm901755g
Publikováno v:
British Journal of Cancer
Background: Neuropilin-1 (NRP1) is a non-tyrosine kinase receptor for vascular endothelial growth factor (VEGF) recently implicated in tumour functions. Methods: In this study we used a specific antagonist of VEGF binding to the NRP1 b1 domain, EG328
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25878a1e71f6d24d99c9d7bf24b5587a
https://doi.org/10.1038/sj.bjc.6605539
https://doi.org/10.1038/sj.bjc.6605539
Autor:
Ian Zachary, Pauliina Lehtolainen, Paul Frankel, Giovanna M. D'Abaco, Lili Cheng, Caroline Pellet-Many, Michelle Tickner
Publikováno v:
EMBO reports. 9:983-989
Neuropilin 1 (NRP1), a non-tyrosine kinase receptor for vascular endothelial growth factor and class 3 Semaphorins, is highly expressed in many human tumour cell lines, but its function is poorly understood. Here, we describe the expression of a new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44f88930198d0d5548e67b4b129a867
https://doi.org/10.1038/embor.2008.151
https://doi.org/10.1038/embor.2008.151
Autor:
Arleen B. Rifkind, Terence L. Kirley, Michelle Tickner, Aaron J. Marcus, Silvia Diani-Moore, Joan H.F. Drosopoulos, Emily Wood, Naziba Islam, M. Johan Broekman, Joshua I Park
Publikováno v:
Archives of Biochemistry and Biophysics. 407:49-62
We report here that induction of ectoATPase by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is cell-type specific and not a generalized response to aryl hydrocarbon (Ah) receptor activation. TCDD increased [14C]-ATP and -ADP metabolism in two mouse hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380f4fe691b1002b1aabc75c839c0868
https://doi.org/10.1016/s0003-9861(02)00465-4
https://doi.org/10.1016/s0003-9861(02)00465-4
Autor:
Basil Hartzoulakis, Ashley Jarvis, Azadeh Bagherzadeh, Lili Cheng, Diego Esposito, Haiyan Jia, Shaheda Shaikh, Paul C. Driscoll, Marianne Löhr, Ian Zachary, Michelle Tickner, David L. Selwood, Richard Harris, Rehan Aqil
Publikováno v:
The Journal of biological chemistry. 281(19)
Neuropilin-1 (NP-1) is a receptor for vascular endothelial growth factor-A165 (VEGF-A165) in endothelial cells. To define the role of NP-1 in the biological functions of VEGF, we developed a specific peptide antagonist of VEGF binding to NP-1 based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737bc2ba5a94f49e460b12887555447d
https://pubmed.ncbi.nlm.nih.gov/16513643
https://pubmed.ncbi.nlm.nih.gov/16513643