Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michelle Spata"'
Autor:
Daniel Ackerman, Sergey Tumanov, Bo Qiu, Evdokia Michalopoulou, Michelle Spata, Andrew Azzam, Hong Xie, M. Celeste Simon, Jurre J. Kamphorst
Publikováno v:
Cell Reports, Vol 24, Iss 10, Pp 2596-2605.e5 (2018)
Summary: Lipid droplets, which store triglycerides and cholesterol esters, are a prominent feature of clear cell renal cell carcinoma (ccRCC). Although their presence in ccRCC is critical for sustained tumorigenesis, their contribution to lipid homeo
Externí odkaz:
https://doaj.org/article/e5eaadd94f7f4231b99f861f6c1183b7
Autor:
M. Celeste Simon, Robert H. Vonderheide, David Allman, Amy C. Durham, Elizabeth L. Buza, Lauren J. Bayne, Michelle Spata, Kyoung Eun Lee
Supplementary Figure S1. HIF1α is dispensable for pancreas development. Supplementary Figure S2. Additional characterization of KrasG12D;Hif1αKO animals. Supplementary Figure S3. Disease spectrum of KrasG12D and KrasG12D;Hif1αKO mice. Supplementar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9acda295d82c1339633a3b09826394
https://doi.org/10.1158/2159-8290.22531434
https://doi.org/10.1158/2159-8290.22531434
Summary Pancreatitis is an inflammatory disease of the exocrine pancreas and ranks among the most common gastrointestinal disorders. Inflamed tissues frequently experience conditions of insufficient oxygen availability, or hypoxia. Here, we demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f37e21841c759130793a532c74d524
https://europepmc.org/articles/PMC6154493/
https://europepmc.org/articles/PMC6154493/
Autor:
David M. Ornitz, Phillip D. Holler, Oh Sang Kwon, Zhikun Zhang, George Cotsarelis, Maksim V. Plikus, Arben Nace, Sarah E. Millar, Xiaohong Zhang, Mayumi Ito, Sheena Baratono, Fen Wang, Michelle Spata, Chang D Kim, Elsa Treffeisen, Zaixin Yang
Publikováno v:
Nature Medicine. 19:916-923
Understanding molecular mechanisms for regeneration of hair follicles provides new opportunities for developing treatments for hair loss and other skin disorders. Here we show that fibroblast growth factor 9 (Fgf9), initially secreted by γδ T cells
Autor:
Lauren J. Bayne, Michelle Spata, Robert H. Vonderheide, Amy C. Durham, David Allman, Kyoung Eun Lee, Elizabeth L. Buza, M. Celeste Simon
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related deaths worldwide, with an exceedingly low 5-year survival rate. PDAC tumors are characterized by an extensive desmoplastic stromal response and hypovascularity, suggesting t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c110fa550be14a5567fc87939346692a
https://europepmc.org/articles/PMC4783189/
https://europepmc.org/articles/PMC4783189/