Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Michelle Somerville"'
Autor:
Emma Jones, Andrew Godkin, Sarah Nicol Lauder, Kathryn Smart, Veerle Kersemans, Danny Allen, Jake Scott, Ana Pires, Stefan Milutinovic, Michelle Somerville, Sean Smart, Paul Kinchesh, Elena Lopez-Guadamillas, Ellyn Hughes, Martin Scurr, Lori S Friedman, Bart Vanhaesebroeck, Awen Gallimore
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Despite striking successes, immunotherapies aimed at increasing cancer-specific T cell responses are unsuccessful in most patients with cancer. Inactivating regulatory T cells (Treg) by inhibiting the PI3Kδ signaling enzyme has shown prom
Externí odkaz:
https://doaj.org/article/03253b8693d64d3c84a6f9eeb342088e
Autor:
Stefan Milutinovic, Jun Abe, Emma Jones, Inken Kelch, Kathryn Smart, Sarah N. Lauder, Michelle Somerville, Carl Ware, Andrew Godkin, Jens V. Stein, Gib Bogle, Awen Gallimore
Publikováno v:
Cancer Research Communications. 2:1641-1656
High endothelial venules (HEV) are specialized post capillary venules that recruit naïve T cells and B cells into secondary lymphoid organs (SLO) such as lymph nodes (LN). Expansion of HEV networks in SLOs occurs following immune activation to suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f421d60081ee93185577183075cec8d
https://doi.org/10.1158/2767-9764.crc-21-0123
https://doi.org/10.1158/2767-9764.crc-21-0123
Autor:
Awen Gallimore, Gib Bogle, Jens V. Stein, Andrew Godkin, Carl Ware, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Inken Kelch, Emma Jones, Jun Abe, Stefan Milutinovic
LSFM imaging of Treg depleted and T-cell depleted fibrosarcomas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2ed8104e7626ae8079b272490919e5
https://doi.org/10.1158/2767-9764.22546256
https://doi.org/10.1158/2767-9764.22546256
Autor:
Awen Gallimore, Andrew Godkin, Robert Andrews, William J. Watkins, Matthew J. Smalley, Rhiannon French, James P. Hindley, Howard Kendrick, Stefan Milutinovic, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Emma Jones, Alexander Greenshields-Watson, Ana Pires
Supplementary Figures 1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d486884604d87cab99475a87091a408
https://doi.org/10.1158/2326-6066.22543605.v1
https://doi.org/10.1158/2326-6066.22543605.v1
Autor:
Awen Gallimore, Gib Bogle, Jens V. Stein, Andrew Godkin, Carl Ware, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Inken Kelch, Emma Jones, Jun Abe, Stefan Milutinovic
High endothelial venules (HEV) are specialized post capillary venules that recruit naïve T cells and B cells into secondary lymphoid organs (SLO) such as lymph nodes (LN). Expansion of HEV networks in SLOs occurs following immune activation to suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e518ba5cab64bb4d5b9752e29a0b0da
https://doi.org/10.1158/2767-9764.c.6551132.v1
https://doi.org/10.1158/2767-9764.c.6551132.v1
Autor:
Awen Gallimore, Andrew Godkin, Robert Andrews, William J. Watkins, Matthew J. Smalley, Rhiannon French, James P. Hindley, Howard Kendrick, Stefan Milutinovic, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Emma Jones, Alexander Greenshields-Watson, Ana Pires
The nature of the tumor microenvironment (TME) influences the ability of tumor-specific T cells to control tumor growth. In this study, we performed an unbiased comparison of the TME of regulatory T-cell (Treg)–replete and Treg-depleted carcinogen-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd1b36ae44d938b2dc48a4d25e36406
https://doi.org/10.1158/2326-6066.c.6550332
https://doi.org/10.1158/2326-6066.c.6550332
Autor:
Awen Gallimore, Gib Bogle, Jens V. Stein, Andrew Godkin, Carl Ware, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Inken Kelch, Emma Jones, Jun Abe, Stefan Milutinovic
Global overview of intra-tumoral HEVs in a 4T1 regressor tumour following PI-3065 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466fe82b9967c7ea1f9fe51d9113da4d
https://doi.org/10.1158/2767-9764.22546244.v1
https://doi.org/10.1158/2767-9764.22546244.v1
Autor:
Awen Gallimore, Gib Bogle, Jens V. Stein, Andrew Godkin, Carl Ware, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Inken Kelch, Emma Jones, Jun Abe, Stefan Milutinovic
Global overview of intra-tumoral HEVs in a 4T1 regressor tumour following PI-3065 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e944befcda97f2cc10fb832aa8210f
https://doi.org/10.1158/2767-9764.22546241.v1
https://doi.org/10.1158/2767-9764.22546241.v1
Autor:
Awen Gallimore, Gib Bogle, Jens V. Stein, Andrew Godkin, Carl Ware, Michelle Somerville, Sarah N. Lauder, Kathryn Smart, Inken Kelch, Emma Jones, Jun Abe, Stefan Milutinovic
Global overview of intra-tumoral HEVs in a 4T1 non-regressor tumour following PI-3065 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27be105a2d529ce9ecfa31a2bb2c218f
https://doi.org/10.1158/2767-9764.22546235
https://doi.org/10.1158/2767-9764.22546235
Autor:
Aleksandra Frankow, Andrew C. Newby, Jason L. Johnson, Christopher L. Jackson, Sarah J George, Karina Di Gregoli, Rosaria Bianco, Michelle Somerville, Aniita C. Thomas
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Galectin-3 (formerly known as Mac-2), encoded by the LGALS3 gene, is proposed to regulate macrophage adhesion, chemotaxis, and apoptosis. We investigated the role of galectin-3 in
Objective: Galectin-3 (formerly known as Mac-2), encoded by the LGALS3 gene, is proposed to regulate macrophage adhesion, chemotaxis, and apoptosis. We investigated the role of galectin-3 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77534c245c7a509c6c8d4bab1b7d2952
https://doi.org/10.1161/atvbaha.120.314252
https://doi.org/10.1161/atvbaha.120.314252