Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michelle Simpson-Abelson"'
Autor:
Richard B Bankert, Sathy V Balu-Iyer, Kunle Odunsi, Leonard D Shultz, Raymond J Kelleher, Jennifer L Barnas, Michelle Simpson-Abelson, Robert Parsons, Sandra J Yokota
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24420 (2011)
Ovarian cancer is the most common cause of death from gynecological cancer. Understanding the biology of this disease, particularly how tumor-associated lymphocytes and fibroblasts contribute to the progression and metastasis of the tumor, has been i
Externí odkaz:
https://doaj.org/article/4a0c79cad6b74baa884cf56dcd3f5a1b
Autor:
Juan Agustin Cruz, Erin Childs, Nilesh Amatya, Michelle Simpson-Abelson, Abhishek Garg, Rudi Beyaert, Brian Aneskievich, Averil Ma, Sarah L Gaffen
Publikováno v:
The Journal of Immunology. 198:61.3-61.3
IL-17 is a pro-inflammatory cytokine that drives autoimmune diseases and promotes immunity to fungi. IL-17 binding to the IL-17 receptor initiates recruitment of adaptor proteins that activate NF-κB. IL-17 also induces expression of A20, a feedback
Autor:
Krit Ritthipichai, Marcus Machin, Michelle Simpson-Abelson, Christopher Mosychuk, Anand Veerapathran, Michael Lotze
Publikováno v:
The Journal of Immunology. 198:198.1-198.1
Only two K+ channels are known to be expressed by T-cells. Activated effector T cells express high levels of Kv1.3; activated naïve and central memory T-cell subsets express high levels of KCa3.1. Overexpression of Kv1.3 in murine T-cells increases
Autor:
Michelle Simpson-Abelson, Erin Childs, Shrinivas Bishu, Norma Solis, Satoshi Uematsu, Heather Conti, Shizuo Akira, Scott Filler, Sarah Gaffen
Publikováno v:
The Journal of Immunology. 194:132.9-132.9
Th17 cells and IL-17 play essential host-defensive roles in immunity to pathogens, particularly the commensal microbe Candida albicans. Although best known for activation of NF-κB, IL-17 potently activates CCAAT enhancer binding protein transcriptio
Autor:
Heather Conti, Alanna Peterson, Nydiaris Hernandez-Santos, Lucas Brane, Anna Huppler, Natasha Whibley, Kristia Hamilton, Abhishek Garg, Shrinivas Bishu, Michelle Simpson-Abelson, Anna Mamo, David Artis, Angus Thomson, Simon Watkins, Mandy McGeachy, Sarah Gaffen
Publikováno v:
The Journal of Immunology. 192:197.1-197.1
Oropharyngeal candidiasis (OPC) is an opportunistic mucosal infection caused by the commensal fungus Candida albicans. To date, there is a paucity of research on oral mucosal immunity in general and to fungi in particular. Humans with rare mutations
Autor:
Shrinivas Bishu, Nydiaris Hernandez-Santos, Michelle Simpson-Abelson, Anna Huppler, Heather Conti, Nico Ghilardi, Anna Mamo, Xin Lin, Sarah Gaffen
Publikováno v:
The Journal of Immunology. 192:132.5-132.5
Oropharyngeal candidiasis (OPC, thrush) is an opportunistic infection caused by the commensal fungus Candida albicans. OPC is common in individuals with HIV/AIDS, infants, and individuals with congenital immune defects. Immunity to OPC is dependent o
Publikováno v:
The Journal of Immunology. 192:63.13-63.13
Th17 cells and IL-17 play essential host-defensive roles in immunity to pathogens, particularly fungi such as Candida albicans. However, the specific signaling pathways used by IL-17 and its receptor are still poorly defined. We have shown that IL-17