Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michelle Sempkowski"'
Autor:
Stavroula Sofou, Alfred Morgenstern, Frank Bruchertseifer, Martin G. Pomper, Sangeeta Ray Banerjee, Michelle Sempkowski, Amey Bandekar, Charles Zhu
This study aims to evaluate the effect on killing efficacy of the intracellular trafficking patterns of α-particle emitters by using different radionuclide carriers in the setting of targeted antivascular α-radiotherapy. Nanocarriers (lipid vesicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f38227956279c2ebc6e780234dec488
https://doi.org/10.1158/1535-7163.c.6537633
https://doi.org/10.1158/1535-7163.c.6537633
Autor:
Stavroula Sofou, Alfred Morgenstern, Frank Bruchertseifer, Martin G. Pomper, Sangeeta Ray Banerjee, Michelle Sempkowski, Amey Bandekar, Charles Zhu
Viability (evaluated after one doubling time) of PSMA-positive HUVEC as a function of delivered radioactivity per cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ef343fa013d26495acd921df7ed0f5
https://doi.org/10.1158/1535-7163.22504143
https://doi.org/10.1158/1535-7163.22504143
Autor:
Stavroula Sofou, Alfred Morgenstern, Frank Bruchertseifer, Martin G. Pomper, Sangeeta Ray Banerjee, Michelle Sempkowski, Amey Bandekar, Charles Zhu
Effect on vesicles' targeting of the content of urea-based PSMA targeting ligand, and structure of the non active targeting construct (negative control) and of the free urea-based ligand.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135b508f80c6c32758ac4c9be53ac22b
https://doi.org/10.1158/1535-7163.22504158.v1
https://doi.org/10.1158/1535-7163.22504158.v1
Autor:
Stavroula Sofou, Alfred Morgenstern, Frank Bruchertseifer, Martin G. Pomper, Sangeeta Ray Banerjee, Michelle Sempkowski, Amey Bandekar, Charles Zhu
Effect of flow field on viability of PSMA-positive HUVEC as a function of delivered radioactivity per cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::391c29b7e80b8377a6cd6b5389192435
https://doi.org/10.1158/1535-7163.22504140
https://doi.org/10.1158/1535-7163.22504140
Autor:
Stavroula Sofou, Alfred Morgenstern, Frank Bruchertseifer, Martin G. Pomper, Sangeeta Ray Banerjee, Michelle Sempkowski, Amey Bandekar, Charles Zhu
Dissociation constants for targeted vesicle constructs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e6d72f457449dc40b6d7c35168e17f
https://doi.org/10.1158/1535-7163.22504155.v1
https://doi.org/10.1158/1535-7163.22504155.v1
Autor:
Stavroula Sofou, Alfred Morgenstern, Frank Bruchertseifer, Martin G. Pomper, Sangeeta Ray Banerjee, Michelle Sempkowski, Amey Bandekar, Charles Zhu
Effect of the presence of CCM on PSMA expression over time.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e2fc77d6f3f0485f229213cf820a3d
https://doi.org/10.1158/1535-7163.22504149
https://doi.org/10.1158/1535-7163.22504149
Autor:
Stavroula Sofou, Alfred Morgenstern, Frank Bruchertseifer, Martin G. Pomper, Sangeeta Ray Banerjee, Michelle Sempkowski, Amey Bandekar, Charles Zhu
Viability (evaluated after one doubling time) of PSMA-positive HUVEC in monolayers after treatment by targeted radiolabeled constructs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a92bde0024f6e01607fef36c15488ca
https://doi.org/10.1158/1535-7163.22504146
https://doi.org/10.1158/1535-7163.22504146
Autor:
Stavroula Sofou, Alfred Morgenstern, Frank Bruchertseifer, Martin G. Pomper, Sangeeta Ray Banerjee, Michelle Sempkowski, Amey Bandekar, Charles Zhu
Demonstration of enhanced expression of PSMA by HUVEC exposed to cell cultured media.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e1c08b8a03678546df99544c73b404
https://doi.org/10.1158/1535-7163.22504152
https://doi.org/10.1158/1535-7163.22504152
Autor:
George Sgouros, Stavroula Sofou, Omkar Bhatavdekar, Dominick Salerno, Alaina Howe, Aprameya Prasad, Rajiv Nair, Michelle Sempkowski, Kathleen L. Gabrielson, Jesus Pacheco-Torres, Zaver M. Bhujwalla, Anders Josefsson
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 48:4246-4258
Highly cytotoxic α-particle radiotherapy delivered by tumor-selective nanocarriers is evaluated on metastatic Triple Negative Breast Cancer (TNBC). On vascularized tumors, the limited penetration of nanocarriers (
Autor:
Charles Zhu, Michelle Sempkowski, Stavroula Sofou, Frank Bruchertseifer, Ioannis G. Kevrekidis, Monica Zofia Menzenski, Alfred Morgenstern
Publikováno v:
Langmuir. 32:8329-8338
Effective targeting by uniformly functionalized nanoparticles is limited to cancer cells expressing at least two copies of targeted receptors per nanoparticle footprint (approximately ≥2 × 10(5) receptor copies per cell); such a receptor density s