Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Michelle Seif"'
Autor:
P. Lewis White, Jan Springer, Matt P. Wise, Hermann Einsele, Claudia Löffler, Michelle Seif, Sabrina Prommersberger, Matthijs Backx, Jürgen Löffler
Publikováno v:
Journal of Fungi, Vol 8, Iss 1, p 81 (2022)
The COVID-19 pandemic has resulted in large numbers of patients requiring critical care management. With the established association between severe respiratory virus infection and invasive pulmonary aspergillosis (7.6% for COVID-19-associated pulmona
Externí odkaz:
https://doaj.org/article/efe845a2579c447080bbf98a4ec3a177
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Infectious diseases are still a significant cause of morbidity and mortality worldwide. Despite the progress in drug development, the occurrence of microbial resistance is still a significant concern. Alternative therapeutic strategies are required f
Externí odkaz:
https://doaj.org/article/dccffadc9b0a4b74a943e7ea81563c1a
Autor:
Michelle Seif, Tamara Katharina Kakoschke, Frank Ebel, Marina Maria Bellet, Nora Trinks, Giorgia Renga, Marilena Pariano, Luigina Romani, Beeke Tappe, David Espie, Emmanuel Donnadieu, Kerstin Hünniger, Antje Häder, Markus Sauer, Diane Damotte, Marco Alifano, P. Lewis White, Matthijs Backx, Thomas Nerreter, Markus Machwirth, Oliver Kurzai, Sabrina Prommersberger, Hermann Einsele, Michael Hudecek, Jürgen Löffler
Publikováno v:
Science Translational Medicine. 14
Aspergillus fumigatus is a ubiquitous mold that can cause severe infections in immunocompromised patients, typically manifesting as invasive pulmonary aspergillosis (IPA). Adaptive and innate immune cells that respond to A. fumigatus are present in t
Publikováno v:
Current opinion in microbiology. 58
Invasive fungal infections mainly occur in patients suffering from impaired immunity. Their associated mortality is high despite antifungal treatment. Thus, several efforts have been made to translate our knowledge on protective antifungal immunity i
Autor:
Anja A. Kühl, Alexander Scheffold, Olaf Kniemeyer, Josephine Schlosser, Jan Springer, Kerstin Rosen, Axel A. Brakhage, Michelle Seif, Petra Bacher, Jürgen Löffler, Friederike Ebner, Uwe Rösler, Lydia Scharek-Tedin, Susanne Hartmann, Stefanie Schmidt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aa17ef7c390d4e9979b6f6ce8a785b3
https://doi.org/10.1002/eji.201948524/v2/response1
https://doi.org/10.1002/eji.201948524/v2/response1
Autor:
Uwe Rösler, Axel A. Brakhage, Susanne Hartmann, Jan Springer, Petra Bacher, Lydia Scharek-Tedin, Michelle Seif, Olaf Kniemeyer, Josephine Schlosser, Alexander Scheffold, Jürgen Löffler, Friederike Ebner, Stefanie Schmidt, Kerstin Rosen, Anja A. Kühl
Pulmonary mucosal immune response is critical for preventing opportunistic Aspergillus fumigatus infections. Although fungus‐specific CD4\(^{+}\) T cells in blood are described to reflect the actual host–pathogen interaction status, little is kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce755b7f1affb6dda845f18157182e8
Macrophages have increasingly gained interest as a therapeutic target since they represent an integral component of the tumor microenvironment. In fact, M2 macrophage accumulation in solid tumors is associated with poor prognosis and therapy failure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10d8c38147f2285830f1f3a2a8e91c0
Publikováno v:
Inflammation. 39:1690-1703
Macrophages are a heterogeneous and plastic cell population with two main phenotypes: pro-inflammatory classically activated macrophages (M1) and anti-inflammatory alternatively activated macrophages (M2). Saccharomyces cerevisiae is a promising vehi
Autor:
Andrew R. Findlay, Sarah E. Robinson, Stephanie Poelker, Michelle Seiffert, Rocio Bengoechea, Conrad C. Weihl
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 2, Pp 181-194 (2023)
ABSTRACT Objective To delineate the full phenotypic spectrum and characterize the natural history of limb girdle muscular dystrophy type D1 (LGMDD1). Methods We extracted age at clinical events of interest contributing to LGMDD1 disease burden via a
Externí odkaz:
https://doaj.org/article/df6f0a45ecd440df9b017670faeb1e15
Autor:
Jessica Hoppstädter, Hanno Huwer, Annette Kraegeloh, Anna Dembek, Christian Cavelius, Michelle Seif, Alexandra K. Kiemer
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Frontiers in Pharmacology
Frontiers in Pharmacology
While silica nanoparticles have enabled numerous industrial and medical applications, their toxicological safety requires further evaluation. Macrophages are the major cell population responsible for nanoparticle clearance in vivo. The prevailing mac