Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michelle S. Libério"'
Autor:
Charles L. Bidgood, Michelle S. Libério, Martin C. Sadowski, Melanie Lehman, Colleen C. Nelson, John D. Wade, Jennifer H. Gunter, Lisa Philp, Anja Rockstroh, Stephen McPherson, Laszlo Otvos, Gregor Tevz, Nenad Bartonicek, Atefeh Taherian Fard
Publikováno v:
Philp, Lisa K; Rockstroh, Anja; Sadowski, Martin C; Taherian Fard, Atefeh; Lehman, Melanie; Tevz, Gregor; Libério, Michelle S; Bidgood, Charles L; Gunter, Jennifer H; McPherson, Stephen; Bartonicek, Nenad; Wade, John D; Otvos, Laszlo; Nelson, Colleen C (2021). Leptin antagonism inhibits prostate cancer xenograft growth and progression. Endocrine-related cancer, 28(5), pp. 353-375. BioScientifica Ltd. 10.1530/ERC-20-0405
Hyperleptinaemia is a well-established therapeutic side effect of drugs inhibiting the androgen axis in prostate cancer (PCa), including main stay androgen deprivation therapy (ADT) and androgen targeted therapies (ATT). Given significant crossover b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ea4121f76d184e85e5e2e7dda6b1d9
https://boris.unibe.ch/161800/1/33794502.pdf
https://boris.unibe.ch/161800/1/33794502.pdf
Autor:
Martin C. Sadowski, Colleen C. Nelson, Raj Vasireddy, Melanie Lehman, Anja Rockstroh, Michelle S. Libério, Rohan A. Davis
Publikováno v:
ResearcherID
Oncotarget
Oncotarget
As part of an anti-cancer natural product drug discovery program, we recently identified eusynstyelamide B (EB), which displayed cytotoxicity against MDA-MB-231 breast cancer cells (IC50 = 5 μM) and induced apoptosis. Here, we investigated the mecha
Publikováno v:
Protein & Peptide Letters. 20:380-391
Despite progress in understanding carcinogenesis, cancer is still a major cause of morbidity and mortality worldwide. Treatment is complicated by the resistance to chemotherapeutics acquired by tumors, ability to repair damaged DNA, alteration of the
Publikováno v:
Org. Biomol. Chem.. 11:261-270
Four new acylated pteridine alkaloids, duramidines A-D, two new acylated thymidine alkaloids, leptoclinidines A and B, two new 1-acylglyceryl-3-(O-carboxyhydroxymethylcholine) alkaloids, durabetaines A and B, three new 1,3-dimethyl-5-methylsulfanylim
Autor:
Colleen C. Nelson, Carolina Soekmadji, Michelle S. Libério, Martin C. Sadowski, Rohan A. Davis
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e112122 (2014)
PLoS ONE, Vol 9, Iss 11, p e112122 (2014)
Weak cell-surface adhesion of cell lines to tissue culture surfaces is a common problem and presents technical limitations to the design of experiments. To overcome this problem, various surface coating protocols have been developed. However, a compa
Publikováno v:
Tetrahedron Letters. 52:6729-6731
Chemical investigation of the CH2Cl2/MeOH extract from the Australian ascidian Leptoclinides kingi led to the isolation of a new brominated indole alkaloid, kingamide A (1). The planar structure of kingamide A was elucidated following the interpretat
Publikováno v:
Marine Drugs
Marine Drugs, Vol 12, Iss 10, Pp 5222-5239 (2014)
Volume 12
Issue 10
Pages 5222-5239
Marine Drugs, Vol 12, Iss 10, Pp 5222-5239 (2014)
Volume 12
Issue 10
Pages 5222-5239
Ascidians are marine invertebrates that have been a source of numerous cytotoxic compounds. Of the first six marine-derived drugs that made anticancer clinical trials, three originated from ascidian specimens. In order to identify new anti-neoplastic
Autor:
Mariana S. Castro, Jaime M. Santana, Osmindo Rodrigues Pires Júnior, Izabela Marques Dourado Bastos, Michelle S. Libério, Wagner Fontes
Publikováno v:
PLoS ONE
Repositório Institucional da UnB
Universidade de Brasília (UnB)
instacron:UNB
PLoS ONE, Vol 9, Iss 6, p e96893 (2014)
Repositório Institucional da UnB
Universidade de Brasília (UnB)
instacron:UNB
PLoS ONE, Vol 9, Iss 6, p e96893 (2014)
Peptidases are ubiquitous enzymes involved in diverse biological processes. Fragments from bioactive peptides have been found in skin secretions from frogs, and their presence suggests processing by peptidases. Thus, the aim of this work was to chara
Autor:
Graziella Anselmo Joanitti, Wagner Fontes, Eduardo Maffud Cilli, Mariana S. Castro, Osmindo Rodrigues Pires Júnior, Anna Christina C. Nascimento, Michelle S. Libério, Marcelo Valle de Sousa, Ricardo Bentes Azevedo, Lanuse C. Zanotta
Publikováno v:
Amino Acids
Nowadays, the emergence of resistance to the current available chemotherapeutic drugs by cancer cells makes the development of new agents imperative. The skin secretion of amphibians is a natural rich source of antimicrobial peptides (AMP), and resea