Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michelle S Ong"'
Autor:
Bothayna Al-Gashgari, Alaguraj Veluchamy, Lorena V. Cortés-Medina, Wolfgang Fischle, Zhadyra Yerkesh, Abrar Aljahani, Dulat Azhibek, Sarah Kreuz, Alexander Lemak, Scott Houliston, Papita Mandal, Lixin Fan, Shili Duan, Cheryl H. Arrowsmith, Maria Tauber, Michelle S. Ong
Publikováno v:
Nucleic Acids Research
UHRF1 is an important epigenetic regulator associated with apoptosis and tumour development. It is a multidomain protein that integrates readout of different histone modification states and DNA methylation with enzymatic histone ubiquitylation activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7bfa0e2ba5801462c169fb7c0809ed
https://pubmed.ncbi.nlm.nih.gov/32609811
https://pubmed.ncbi.nlm.nih.gov/32609811
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
High mobility group N proteins (HMGNs) bind specifically to the nucleosome core and act as chromatin unfolding and activating factors. Using an all-Xenopus system, we found that HMGN1 and HMGN2 binding to nucleosomes results in distinct ion-dependent
Externí odkaz:
https://doaj.org/article/963d763e6a22438dbf85d2b957eaba14
Publikováno v:
J Gerontol B Psychol Sci Soc Sci
Objectives To determine whether auditory and visual computer games yield transfer effects that (a) are modality-specific to verbal memory (auditory stimulus presentation) and visual-processing tests, (b) affect working memory and processing speed, (c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533c363a4f5d784547271b6caf316370
https://europepmc.org/articles/PMC7265809/
https://europepmc.org/articles/PMC7265809/
Autor:
Danton Ivanochko, Peter Brown, Lixin Fan, Shili Duan, Guillermo Senisterra, Cheryl H. Arrowsmith, Alexander Lemak, Aman Iqbal, Lilia Kaustov, R. Scott Houliston, Yun-Xing Wang, Michelle S. Ong
Publikováno v:
The Journal of Biological Chemistry
UHRF1 is a key mediator of inheritance of epigenetic DNA methylation patterns during cell division and is a putative target for cancer therapy. Recent studies indicate that interdomain interactions critically influence UHRF1's chromatin-binding prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75ed82e9af224026dfe3bad356e26df
https://pubmed.ncbi.nlm.nih.gov/29074623
https://pubmed.ncbi.nlm.nih.gov/29074623
Autor:
Stefan Winter, Kathy Ann Gelato, Alexander Lemak, Yvette Bultsma, Wolfgang Fischle, Maria Tauber, Julia Sindlinger, Cheryl H. Arrowsmith, Nullin Divecha, Scott Houliston, Dirk Schwarzer, Michelle S. Ong, Kyoko Hiragami-Hamada
Publikováno v:
Molecular Cell
UHRF1 is a multidomain protein crucially linking histone H3 modification states and DNA methylation. While the interaction properties of its specific domains are well characterized, little is known about the regulation of these functionalities. We sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a57481ba762a1b8a9eb4bd8aab8583b
https://doi.org/10.1016/j.molcel.2014.04.004
https://doi.org/10.1016/j.molcel.2014.04.004
Autor:
Michelle S. Ong, Scott B. Rothbart, Dmitri Kireev, Krzysztof Krajewski, Bradley M. Dickson, Cheryl H. Arrowsmith, Brian D. Strahl, Scott Houliston
Publikováno v:
Genes & Development. 27:1288-1298
Histone post-translational modifications regulate chromatin structure and function largely through interactions with effector proteins that often contain multiple histone-binding domains. While significant progress has been made characterizing indivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321926fd5b29aa39e09e62e6f5a4e0ac
https://doi.org/10.1101/gad.220467.113
https://doi.org/10.1101/gad.220467.113
Publikováno v:
Journal of Molecular Biology. 368:1067-1074
DNA stretching in chromatin may facilitate its compaction and influence site recognition by nuclear factors. In vivo, stretching has been estimated to occur at the equivalent of one to two base-pairs (bp) per nucleosome. We have determined the crysta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e440c74c5a572571b23f18f67331f3d
https://doi.org/10.1016/j.jmb.2007.02.062
https://doi.org/10.1016/j.jmb.2007.02.062
Autor:
Michael Groessl, Paul J. Dyson, Curt A. Davey, Bin Wu, Zenita Adhireksan, Michelle S. Ong, Christian G. Hartinger
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 17(13)
Keywords: bioinorganic chemistry ; cancer ; histone binding ; nucleosomes ; Rapta-C ; ruthenium ; Mass-Spectrometry ; Anticancer Metallodrugs ; Complexes ; Chromatin ; Binding ; Dna ; Particle ; Chemotherapy ; Selectivity ; Inhibition Reference EPFL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d529bd02c256c48d1824996cbc6981
https://pubmed.ncbi.nlm.nih.gov/21344528
https://pubmed.ncbi.nlm.nih.gov/21344528
Publikováno v:
Journal of Nucleic Acids
Journal of Nucleic Acids, Vol 2010 (2010)
Journal of Nucleic Acids, Vol 2010 (2010)
High mobility group N proteins (HMGNs) bind specifically to the nucleosome core and act as chromatin unfolding and activating factors. Using an all-Xenopussystem, we found that HMGN1 and HMGN2 binding to nucleosomes results in distinct ion-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b148a5b16a6fab653ef6f0343de09d8d
Autor:
Scott B. Rothbart, Bradley M. Dickson, Michelle S. Ong, Krzysztof Krajewski, Brian D. Strahl, Scott Houliston, Cheryl H. Arrowsmith, Dmitri Kireev
Publikováno v:
Cancer Research. 73:PR03-PR03
DNA methylation and histone post-translational modifications (PTMs) represent two key epigenetic regulators of DNA information in chromatin. The faithful inheritance of DNA methylation is essential for normal mammalian development and long-term trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::435083276e8c7efd444fec82e3bdbd7a
https://doi.org/10.1158/1538-7445.cec13-pr03
https://doi.org/10.1158/1538-7445.cec13-pr03