Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michelle R Robinson"'
Autor:
Joshua E Mayfield, Seema Irani, Edwin E Escobar, Zhao Zhang, Nathaniel T Burkholder, Michelle R Robinson, M Rachel Mehaffey, Sarah N Sipe, Wanjie Yang, Nicholas A Prescott, Karan R Kathuria, Zhijie Liu, Jennifer S Brodbelt, Yan Zhang
Publikováno v:
eLife, Vol 8 (2019)
The Positive Transcription Elongation Factor b (P-TEFb) phosphorylates Ser2 residues of the C-terminal domain (CTD) of the largest subunit (RPB1) of RNA polymerase II and is essential for the transition from transcription initiation to elongation in
Externí odkaz:
https://doaj.org/article/53e0122eb0c34ddbb874f06e2b7e518b
Autor:
Daniel S. Spellman, Gia Jokhadze, Christian Hoppmann, Mandy Li, Lisa A Vasicek, Michelle R. Robinson
Publikováno v:
The Analyst. 145(8)
Continued interest in protein therapeutics has motivated the development of improved bioanalytical tools to support development programs. LC-MS offers specificity, sensitivity, and multiplexing capabilities without the need for target-specific reagen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bad1aae840774a6c620fec0629813b3
https://pubmed.ncbi.nlm.nih.gov/32191233
https://pubmed.ncbi.nlm.nih.gov/32191233
Autor:
Jennifer S. Brodbelt, Joe R. Cannon, Anjana Ram, Yan Jessie Zhang, David S. Gilmour, Seema Irani, Victoria C. Cotham, Wendy L. Matthews, Joshua E. Mayfield, Michelle R. Robinson
Publikováno v:
ACS Chemical Biology. 12:153-162
Phosphorylation of the C-terminal domain of RNA polymerase II (CTD) plays an essential role in eukaryotic transcription by recruiting transcriptional regulatory factors to the active polymerase. However, the scarcity of basic residues and repetitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f80a773ee02f3768057a5b85a8fb2d4
https://doi.org/10.1021/acschembio.6b00729
https://doi.org/10.1021/acschembio.6b00729
Publikováno v:
Advances in experimental medicine and biology. 1140
Advances in mass spectrometry, proteomics, protein bioanalytical approaches, and biochemistry have led to a rapid evolution and expansion in the area of mass spectrometry-based biomarker discovery and development. The last decade has also seen signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::015416e608c1886973690a4ae86c5ee1
https://pubmed.ncbi.nlm.nih.gov/31347063
https://pubmed.ncbi.nlm.nih.gov/31347063
Autor:
Michelle R. Robinson, Edwin E. Escobar, Jennifer S. Brodbelt, M. Rachel Mehaffey, Nathaniel T. Burkholder, Wanjie Yang, Zhao Zhang, Seema Irani, Karan R. Kathuria, Joshua E. Mayfield, Yan Zhang, Nicholas A Prescott, Sarah N. Sipe, Zhijie Liu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b89da89095279049161cdf2bd54afeb2
https://doi.org/10.7554/elife.48725.020
https://doi.org/10.7554/elife.48725.020
Autor:
Wanjie Yang, Zhao Zhang, M. Rachel Mehaffey, Nathaniel T. Burkholder, Jennifer S. Brodbelt, Michelle R. Robinson, Joshua E. Mayfield, Karan R. Kathuria, Seema Irani, Zhijie Liu, Yan Zhang, Nicholas A Prescott, Sarah N. Sipe, Edwin E. Escobar
SummaryThe Positive Transcription Elongation Factor b (P-TEFb) phosphorylates Ser2 residues of RNA polymerase II’s C-terminal domain (CTD) and is essential for the transition from transcription initiation to elongationin vivo. Surprisingly, P-TEFb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd05bd6f3dfa0c2bf4cc0410adb63a74
Autor:
Nicholas A Prescott, Sarah N. Sipe, Zhao Zhang, Yan Zhang, Edwin E. Escobar, Wanjie Yang, M. Rachel Mehaffey, Michelle R. Robinson, Joshua E. Mayfield, Zhijie Liu, Karan R. Kathuria, Nathaniel T. Burkholder, Seema Irani, Jennifer S. Brodbelt
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
The Positive Transcription Elongation Factor b (P-TEFb) phosphorylates Ser2 residues of the C-terminal domain (CTD) of the largest subunit (RPB1) of RNA polymerase II and is essential for the transition from transcription initiation to elongation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d5a63208b9fb6896b8ffab730ed9e3
https://pubmed.ncbi.nlm.nih.gov/31385803
https://pubmed.ncbi.nlm.nih.gov/31385803
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030159498
Advances in mass spectrometry, proteomics, protein bioanalytical approaches, and biochemistry have led to a rapid evolution and expansion in the area of mass spectrometry-based biomarker discovery and development. The last decade has also seen signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0409634a5293639a6e456f35b5d81ee
https://doi.org/10.1007/978-3-030-15950-4_25
https://doi.org/10.1007/978-3-030-15950-4_25
Publikováno v:
Analytical Chemistry. 88:11037-11045
Tyrosine sulfation is an important post-translational modification but remains difficult to detect in biological samples owing to its low stoichiometric abundance and the lack of effective enrichment methods. In the present study, weak anion exchange
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f89def4bac63c5218a4e3cdbbe5c45
https://doi.org/10.1021/acs.analchem.6b02899
https://doi.org/10.1021/acs.analchem.6b02899
Publikováno v:
Journal of Proteome Research. 15:2739-2748
Advances in liquid chromatography tandem mass spectrometry (LC-MS/MS) have permitted phosphoproteomic analysis on a grand scale, but ongoing challenges specifically associated with confident phosphate localization continue to motivate the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9689d670c9ac79fe8a075bccd190757b
https://doi.org/10.1021/acs.jproteome.6b00289
https://doi.org/10.1021/acs.jproteome.6b00289