Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michelle Queau"'
Autor:
James B. Johnston, Trina Wang, Susi Snitzler, Harminder Paul, Sumeet Kakar, Suzanne Trudel, Deborah A. Smith, Olga Levina, Ellen N Wei, Christine Chen, Anthea Lau, Michelle Queau, Lisa W. Le
Publikováno v:
Leukemia & Lymphoma. 60:92-100
AKT plays a centralized role in tumor proliferation and survival and is aberrantly activated in chronic lymphocytic leukemia (CLL). In this phase 2 trial, 30 relapsed/refractory CLL patients were treated with combination afuresertib, a novel oral AKT
Autor:
Spencer B. Gibson, James B. Johnston, Danielle C Croucher, Barbara Sherry, Susi Snitzler, Anthea Lau, Ellen N Wei, Michelle Queau, Suzanne Trudel, David Spaner, Christine Chen, Sumeet Kakar, Lisa W. Le, Harminder Paul
Publikováno v:
Leukemialymphoma. 60(4)
Lenalidomide has anti-tumor activity in CLL but can be complicated by tumor lysis syndrome (TLS) and tumor flare (TF). In our previous study using low-dose lenalidomide in treatment-naive CLL, TLS was averted but TF remained frequent and complete res
Autor:
Christine I, Chen, Harminder, Paul, Lisa W, Le, Ellen N, Wei, Susi, Snitzler, Trina, Wang, Olga, Levina, Sumeet, Kakar, Anthea, Lau, Michelle, Queau, James B, Johnston, Deborah A, Smith, Suzanne, Trudel
Publikováno v:
Leukemialymphoma. 60(1)
AKT plays a centralized role in tumor proliferation and survival and is aberrantly activated in chronic lymphocytic leukemia (CLL). In this phase 2 trial, 30 relapsed/refractory CLL patients were treated with combination afuresertib, a novel oral AKT
Autor:
Sara E.F. Kost, James B. Johnston, Spencer B. Gibson, Sachin Katyal, Xibiao Ye, William S. Liang, Élise LaBossière, Michelle Queau, Eric D.J. Bouchard, Versha Banerji
Publikováno v:
Leukemia research. 50
Bendamustine (BEN) has structural similarities to an alkylating agent and a nucleoside analog, and effective against tumor cells that are resistant to standard therapy. In this study we compared the activities of BEN against that of the alkylating ag
Autor:
Teralee R. Burton, Meghan B. Azad, Wenyan Xiao, Elizabeth S. Henson, Akshay Sathya, Epsita Shome, Michelle Queau, Yongqiang Chen, Spencer B. Gibson, David D. Eisenstat
Mcl-1 is an anti-apoptotic Bcl-2 family member that is often over-expressed in the malignant brain tumor glioblastoma (GBM). It has been previously shown that epidermal growth factor receptors up-regulate Mcl-1 contributing to a cell survival respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f5fca8c8b361db7fbc894d8dd0897f1
https://europepmc.org/articles/PMC4990400/
https://europepmc.org/articles/PMC4990400/
Autor:
Versha Banerji, William S. Liang, Michelle Queau, Spencer B. Gibson, James B. Johnston, Xibiao Ye, Sara E.F. Kost, Élise LaBossière, Eric D.J. Bouchard, Sachin Katyal
Publikováno v:
Cancer Research. 76:281-281
Bendamustine (BEN) is a promising new treatment for chronic lymphocytic leukemia (CLL) and may function as an alkylating agent (eg, chlorambucil, CLB) while sharing structural similarities to a nucleoside analogue (eg, fludarabine, FLU). Enhanced cel
Autor:
Suzanne Trudel, Tong (Trina) Wang, Olga Levina, James B. Johnston, Christine Chen, Harminder Paul, Deborah A. Smith, Anthea Lau, Ellen Nong Wei, Lisa W. Le, Michelle Queau, Susi Snitzler
Publikováno v:
Blood. 126:1742-1742
Introduction: Ofatumumab is an anti-CD20 monoclonal antibody with single-agent responses of 47-58% in refractory CLL (Wierda et al 2010) and a median response duration ranging from 5.6-7.1 months. In order to improve upon these results, we combined o