Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Michelle Perner"'
Autor:
Christina Farr Zuend, Alana Lamont, Laura Noel-Romas, Samantha Knodel, Kenzie Birse, Kateryna Kratzer, Peter McQueen, Michelle Perner, Hossaena Ayele, Sarah Mutch, Alicia R. Berard, John J. Schellenberg, Faruk Senturk, Stuart McCorrister, Garrett Westmacott, Fran Mulhall, Bonnie Sandberg, Adelicia Yu, Margaret Burnett, Vanessa Poliquin, Adam D. Burgener
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Background Cervicovaginal inflammation has been linked to negative reproductive health outcomes including the acquisition of HIV, other sexually transmitted infections, and cervical carcinogenesis. While changes to the vaginal microbiome hav
Externí odkaz:
https://doaj.org/article/1af3ea388c5e4f578c6b6afe6c865734
Autor:
Alicia R. Berard, Douglas K. Brubaker, Kenzie Birse, Alana Lamont, Romel D. Mackelprang, Laura Noël-Romas, Michelle Perner, Xuanlin Hou, Elizabeth Irungu, Nelly Mugo, Samantha Knodel, Timothy R. Muwonge, Elly Katabira, Sean M. Hughes, Claire Levy, Fernanda L. Calienes, Douglas A. Lauffenburger, Jared M. Baeten, Connie Celum, Florian Hladik, Jairam Lingappa, Adam D. Burgener
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112474- (2023)
Summary: Bacterial vaginosis (BV) is characterized by depletion of Lactobacillus and overgrowth of anaerobic and facultative bacteria, leading to increased mucosal inflammation, epithelial disruption, and poor reproductive health outcomes. However, t
Externí odkaz:
https://doaj.org/article/7e7c96530b7143479c58b3f44a85ad62
Autor:
Aloysious Ssemaganda, Francois Cholette, Michelle Perner, Cheli Kambaran, Wendy Adhiambo, Peter M. Wambugu, Henok Gebrebrhan, Amy Lee, Faisal Nuhu, Ruth S. Mwatelah, Naima Jahan, Tosin E. Omole, Tabitha Wanjiru, Apollo Gitau, Joshua Kimani, Lyle R. McKinnon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Regulatory T cells (Tregs) play important roles in tissue homeostasis, but few studies have investigated tissue Tregs in the context of genital inflammation, HIV target cell density, and vaginal microbiota in humans. In women from Nairobi (n=64), the
Externí odkaz:
https://doaj.org/article/494025d9bf704595991953ddaa50bf00
Autor:
Laura Noël-Romas, Michelle Perner, Refilwe Molatlhegi, Christina Farr Zuend, Amanda Mabhula, Sarah Hoger, Alana Lamont, Kenzie Birse, Alicia Berard, Stuart McCorrister, Garett Westmacott, Al Leslie, Vanessa Poliquin, Renee Heffron, Lyle R McKinnon, Adam D Burgener
Publikováno v:
PLoS Pathogens, Vol 16, Iss 12, p e1009097 (2020)
Alterations to the mucosal environment of the female genital tract, such as genital inflammation, have been associated with increased HIV acquisition in women. As the microbiome and hormonal contraceptives can affect vaginal mucosal immunity, we hypo
Externí odkaz:
https://doaj.org/article/4aa8c2a61e09450bbe96238e45e65caa
Autor:
Yiran Wang, Laura Noël-Romas, Michelle Perner, Samantha Knodel, Refilwe Molatlhegi, Sarah Hoger, Kenzie Birse, Christina Farr Zuend, Lyle R McKinnon, Adam D Burgener
Publikováno v:
Clinical Infectious Diseases. 76:1372-1381
Background Adolescent girls and young women aged 15‒24 years in sub-Saharan Africa are at disproportionate risk of human immunodeficiency virus (HIV) infection. Given the known association between vaginal microbial dysbiosis and HIV susceptibility,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdee0657ddd93fc4da0949c022811c55
https://doi.org/10.1093/cid/ciac938
https://doi.org/10.1093/cid/ciac938
Autor:
Yiran, Wang, Laura, Noël-Romas, Michelle, Perner, Samantha, Knodel, Refilwe, Molatlhegi, Sarah, Hoger, Kenzie, Birse, Christina Farr, Zuend, Lyle R, McKinnon, Adam D, Burgener
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
Adolescent girls and young women aged 15-24 in sub-Saharan Africa are at disproportionate risk of HIV infection. Given the known association between vaginal microbial dysbiosis and HIV susceptibility, we performed an age-stratified analysis of the va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eecdedb8d3c9a916ec2e9003b764558a
https://pubmed.ncbi.nlm.nih.gov/36504254
https://pubmed.ncbi.nlm.nih.gov/36504254
Autor:
Christina Farr Zuend, Alana Lamont, Laura Noel-Romas, Samantha Knodel, Kenzie Birse, Kateryna Kratzer, Peter McQueen, Michelle Perner, Hossaena Ayele, Sarah Mutch, Alicia R. Berard, John J. Schellenberg, Faruk Senturk, Stuart McCorrister, Garrett Westmacott, Fran Mulhall, Bonnie Sandberg, Adelicia Yu, Margaret Burnett, Vanessa Poliquin, Adam D. Burgener
Background: Cervicovaginal inflammation has been linked to negative reproductive health outcomes including acquisition of HIV, other sexually transmitted infections, and cervical carcinogenesis. While changes to the vaginal microbiome have been linke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e52252426642abe54cd934b54952cf18
https://doi.org/10.21203/rs.3.rs-1674482/v1
https://doi.org/10.21203/rs.3.rs-1674482/v1
Autor:
Lyle R. McKinnon, Christina Farr Zuend, Adam Burgener, Hossaena Ayele, Michelle Perner, Kenzie Birse
Publikováno v:
American Journal of Reproductive Immunology
Background Access to safe, effective, and affordable contraception is important for women’s health and essential to mitigate maternal and fetal mortality rates. The progestin‐based contraceptive depot medroxyprogesterone acetate (DMPA) is a popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8097e82a33d45c6632c6f4a8b1c1f72a
https://doi.org/10.1111/aji.13455
https://doi.org/10.1111/aji.13455
Autor:
Adam Burgener, Irene Y. Xie, Quarraisha Abdool Karim, Salim S. Abdool Karim, Alexander S. Zevin, Nichole R. Klatt, Michelle Perner, Laura Noël-Romas, Jennifer. Butler, Lyle R. McKinnon, Leila E. Mansoor, Anna Christina. Grobler, Kenzie Birse, Jo-Ann S. Passmore, Garrett Westmacott, Ryan Cheu
Publikováno v:
Science. 356:938-945
Antiretroviral-based strategies for HIV prevention have shown inconsistent results in women. We investigated whether vaginal microbiota modulated tenofovir gel microbicide efficacy in the CAPRISA (Centre for the AIDS Program of Research in South Afri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6896faf52c60ab62adabac038b3674
https://doi.org/10.1126/science.aai9383
https://doi.org/10.1126/science.aai9383
Autor:
Cobi E. Wiwchar, Marlon De Leon, Lucy Karp, Vanessa Poliquin, Alicia R. Berard, Kenzie Birse, Hossaena Ayele, Helen C. Pymar, Alana Lamont, Christina Farr Zuend, Michelle Perner, Laura Noël-Romas, Max Abou, Adam Burgener
Publikováno v:
Journal of Obstetrics and Gynaecology Canada. 42:668-669
Objectives Bacterial vaginosis (BV) is a common gynecologic complaint, prone to recurrence, with limited therapeutic options. The purpose of this study is to identify bacterial or host drivers of BV recurrences. Methods A prospective study of women w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5d21db3a368b126fddd3a1d996b1cef
https://doi.org/10.1016/j.jogc.2020.02.023
https://doi.org/10.1016/j.jogc.2020.02.023