Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michelle Pemberton"'
Autor:
Jonathan D Lea, Robert J. Young, Duncan S. Holmes, Christopher P. Tinworth, Jonathan P. Hutchinson, Semra Kitchen, Justyna Wojno-Picon, Leng Nickels, Michelle Pemberton, Hester Sheehan, Justyna Korczynska, Margarete Neu, Jessica L. Schneck, Efstratios Stratikos, Despoina Koumantou, Iain Uings, Ted Cecconie, Alex Phillipou, Emma J. Jones, John Liddle, Paul Rowland
Publikováno v:
Journal of medicinal chemistry. 63(6)
ER aminopeptidase 1 (ERAP1) is an intracellular enzyme that generates antigenic peptides and is an emerging target for cancer immunotherapy and the control of autoimmunity. ERAP1 inhibitors described previously target the active site and are limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a308daba45dd112f8cbd5048d0a1cc
https://pubmed.ncbi.nlm.nih.gov/32109056
https://pubmed.ncbi.nlm.nih.gov/32109056
Autor:
Rab K. Prinjha, Alex Preston, Inma Rioja, Roy Katso, Melanie Leveridge, Chun-wa Chung, Michael David Barker, Laurens Kruidenier, Gerard Joberty, Kevin Lee, Onkar M. P. Singh, Joanna Taylor, Matthew Campbell, Michelle Pemberton, Fiona Brown, Robert Eagle, Carl Haslam, David Matthew Wilson, Neil Stuart Garton, Tracy Jane Shipley, Colin J. Suckling, Philip G. Humphreys, Gerard Drewes, Laurie J. Gordon, Pamela Thomas, Jack A. Brown, Gail A. Seal, Thomas George Christopher Hayhow, Susan Marie Westaway
Publikováno v:
Journal of Medicinal Chemistry. 59:1370-1387
Following the discovery of cell penetrant pyridine-4-carboxylate inhibitors of the KDM4 (JMJD2) and KDM5 (JARID1) families of histone lysine demethylases (e.g., 1), further optimization led to the identification of non-carboxylate inhibitors derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd41f32203668dbba76c4b0b0fbc2e4
https://doi.org/10.1021/acs.jmedchem.5b01538
https://doi.org/10.1021/acs.jmedchem.5b01538
Publikováno v:
Water Environment & Technology, 1994 Aug 01. 6(8), 37-38.
Externí odkaz:
https://www.jstor.org/stable/24663829
Autor:
John Hellicar, Neil Hardy, Peter S. Marshall, Arne Fuetterer, Michelle Pemberton, Melanie Leveridge, Anja Resemannand, Rainer Paape, Carl Haslam, Adrian J. Dunn
Publikováno v:
Journal of biomolecular screening. 21(2)
Mass spectrometry (MS) offers a label-free, direct-detection method, in contrast to fluorescent or colorimetric methodologies. Over recent years, solid-phase extraction-based techniques, such as the Agilent RapidFire system, have emerged that are cap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31eabe9c872bb2369e067716ef1cf506
https://pubmed.ncbi.nlm.nih.gov/26428484
https://pubmed.ncbi.nlm.nih.gov/26428484