Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michelle Padget"'
Autor:
Kathleen E. Fenerty, Michelle Padget, Benjamin Wolfson, Sofia R. Gameiro, Zhen Su, John H. Lee, Shahrooz Rabizadeh, Patrick Soon-Shiong, James W. Hodge
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Background Poly (ADP-ribose) polymerase inhibitors (PARPi) prevent single-stranded DNA repair. Olaparib is a PARPi approved for the treatment of BRCA mutant ovarian and breast carcinoma. Emerging clinical data suggest a benefit of combining
Externí odkaz:
https://doaj.org/article/4f6eac2c2b1c4a31bc564e9a3f29ade8
Autor:
Jay Friedman, Megan Morisada, Lillian Sun, Ellen C. Moore, Michelle Padget, James W. Hodge, Jeffrey Schlom, Sofia R. Gameiro, Clint T. Allen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Background Natural killer (NK) cells recognize and lyse target tumor cells in an MHC-unrestricted fashion and complement antigen- and MHC-restricted killing by T-lymphocytes. NK cells and T-lymphocytes mediate early killing of targets throug
Externí odkaz:
https://doaj.org/article/9452867cafaa4abaadb8103de56db9b3
Autor:
Kathleen E. Fenerty, Michelle Padget, Benjamin Wolfson, Sofia R. Gameiro, Zhen Su, John H. Lee, Shahrooz Rabizadeh, Patrick Soon-Shiong, James W. Hodge
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-2 (2019)
Following publication of the original article [1], an error was noted in the GAPDH in the western blot depicted in Figure 4b.
Externí odkaz:
https://doaj.org/article/2aaa4f9c0dd249a4b7a5b8f2dfa0bef1
Autor:
Jung-Min Lee, Seth M. Steinberg, Janis M. Taube, Christina M. Annunziata, Stanley Lipkowitz, Marc R. Radke, Elliott Levy, Mohammad H. Bagheri, Erin Nichols, Andrew B. Nixon, James W. Hodge, Elizabeth M. Swisher, Yingmiao Liu, Jayakumar R. Nair, Ashley Cimino-Mathews, Michelle Padget, Alexandra Zimmer, Erika J. Lampert
Supplementary methods, tables, figures 1-5 with corresponding figure legends, and references
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d4e53e79f70b59e1d9a2637b68d09a
https://doi.org/10.1158/1078-0432.22479107.v1
https://doi.org/10.1158/1078-0432.22479107.v1
Autor:
Jung-Min Lee, Seth M. Steinberg, Janis M. Taube, Christina M. Annunziata, Stanley Lipkowitz, Marc R. Radke, Elliott Levy, Mohammad H. Bagheri, Erin Nichols, Andrew B. Nixon, James W. Hodge, Elizabeth M. Swisher, Yingmiao Liu, Jayakumar R. Nair, Ashley Cimino-Mathews, Michelle Padget, Alexandra Zimmer, Erika J. Lampert
Purpose:Preclinical studies suggest PARP inhibition (PARPi) induces immunostimulatory micromilieu in ovarian cancer thus complementing activity of immune checkpoint blockade. We conducted a phase II trial of PARPi olaparib and anti–PD-L1 durvalumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::572309380d18f2e0fb8fb6a6ca8c8066
https://doi.org/10.1158/1078-0432.c.6530135
https://doi.org/10.1158/1078-0432.c.6530135
Autor:
Kara A. Scheibner, Jae-Woong Lee, Kimberly Cramer-Morales, Margaret Nieborowska-Skorska, Mariusz A. Wasik, Mhairi Copland, Tomasz Skorski, Michelle Padget, Curt I. Civin, David Irvine, Huimin Geng, Kimberly Haas, Markus Müschen, Feyruz V. Rassool, Wayne E. Childers, Tomasz Sliwinski, Darshan Roy, Artur Slupianek
Publikováno v:
Blood. 122:1293-1304
Homologous recombination repair (HRR) protects cells from the lethal effect of spontaneous and therapy-induced DNA double-stand breaks. HRR usually depends on BRCA1/2-RAD51, and RAD52-RAD51 serves as back-up. To target HRR in tumor cells, a phenomeno
Autor:
Michelle Padget, Brian J. Druker, Takayo Sasaki, David M. Gilbert, Jared Zimmerman, Connie J. Eaves, Daniel L. Vera, Juan Carlos Rivera-Mulia, Andrew P. Weng, Curt I. Civin, Naoto Nakamichi, Jeffrey W. Tyner, Sunny Das, Bill H. Chang
Publikováno v:
Experimental Hematology. 51:71-82.e3
Genome-wide DNA replication timing (RT) profiles reflect the global 3D chromosome architecture of cells. They also provide a comprehensive and unique megabase-scale picture of the cellular epigenetic state. Thus normal differentiation involves reprod
Publikováno v:
Australian Health Review
Objective: To evaluate cardiac arrest outcomes following the introduction of the Australian Resuscitation Council (ARC) 2006 amended guidelines for basic and advanced life support.\ud \ud Methods: A retrospective study of all consecutive cardiac arre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ccd26a77e7131eef97c049fb4216ab
https://openaccess.city.ac.uk/id/eprint/4566/3/In-hospital_cardiac_arrests__final_post-print_version.pdf
https://openaccess.city.ac.uk/id/eprint/4566/3/In-hospital_cardiac_arrests__final_post-print_version.pdf
Autor:
Alan S. Wayne, Patrick A. Brown, Michelle Padget, Yin Guo, Curt I. Civin, Sebastien Morisot, Srujana Cherukuri, Diana Heckel
Publikováno v:
Cancer Research. 72:3385-3385
Introduction: Pediatric ALL is still fatal in ∼20% of cases, motivating development and clinical trials of novel antineoplastic agents in recurrent ALL such as CD22 monoclonal antibody and immunotoxins. CD22 is expressed on most ALL cases, but not