Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michelle Orlick"'
Autor:
Michelle Orlick, Weichung Shih, Mao Jung Lee, Chung S. Yang, Xi Zheng, Isaac Yi Kim, Susan Goodin
Publikováno v:
Nutr Cancer
The vitamin E forms γ- and δ-tocopherols (T) inhibit carcinogenesis in animal models; nevertheless, their cancer preventive activities in humans are uncertain. As an initial step to address this issue, we conducted a pilot phase 0 trial to determin
Autor:
Salma K. Jabbour, Michelle Orlick, Jyoti Malhotra, Eileen White, Joseph Aisner, Yanxiang Guo, Gregory Riedlinger
Publikováno v:
Cancer Treatment and Research Communications. 21:100158
Objectives Activation of cell survival pathways such as autophagy represents a potential resistance mechanism to chemotherapy in NSCLC. Preclinical studies report that autophagy inhibition suppresses lung tumor development and progression. We report
Autor:
Jyoti Malhotra, Gregory Riedlinger, Eileen White, Michelle Orlick, Sonali Joshi, Joseph Aisner, Salma K. Jabbour, Jessie Yanxiang Guo
Publikováno v:
Journal of Clinical Oncology. 36:e21138-e21138
e21138Background: A potential resistance mechanism to chemotherapy in NSCLC is through activation of cell survival pathways such as autophagy. Studies in genetically engineered mouse models demonst...
Publikováno v:
The Breast Journal. 9:116-119
Treatment of selected patients with anti-HER-2/neu antibodies alone (1) or in combination with chemotherapy (2) may be of benefit to patients with refractory breast cancer. Approximately 30% of breast cancers overexpress HER-2/neu, a member of the ep
Autor:
Judy, Bash-Babula, Deborah, Toppmeyer, Marie, Labassi, Janice, Reidy, Michelle, Orlick, Rachelle, Senzon, Elizabeth, Alli, Thomas, Kearney, David, August, Weichung, Shih, Jin-Ming, Yang, William N, Hait
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 8(5)
Few molecular determinants of sensitivity to cancer chemotherapy exist. In experimental systems, p53 regulates the sensitivity to antimicrotubule drugs through its effect on microtubule-associated protein 4 (MAP4). MAP4 is the major microtubule-assoc