Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Michelle Nicholas"'
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-7 (2023)
Abstract We aimed to determine if a novel digital therapeutic intervention could reduce agitation and unscheduled medication use in an adult delirious acute care population. Delirious participants were randomly allocated (1:1) to receive standard of
Externí odkaz:
https://doaj.org/article/a91858ac9cd04f5e8d70de182e9ef54d
Autor:
Thiago G. Bassi, Michelle Nicholas, Jessica Wittmann, Marlena Ornowska, Karl C. Fernandez, Matt Gani, Steven C. Reynolds
Publikováno v:
Canadian Journal of Respiratory Therapy, Vol 59, Pp 103-110 (2023)
Introduction: Mechanical ventilator breaths provided to deeply sedated patients have an abnormal volume distribution, encouraging alveolar collapse in dependent regions and promoting alveolar overdistention in non-dependent regions. Collapse and over
Externí odkaz:
https://doaj.org/article/c084b2477c104753b8e490cb53c2c589
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ImportanceIdentifying biomarkers that, at hospital admission, predict subsequent delirium will help to focus our clinical efforts on prevention and management.ObjectiveThe study aimed to investigate biomarkers at hospital admission that may be associ
Externí odkaz:
https://doaj.org/article/1656aea316684fbfa2b99adf0d813aef
Autor:
Thiago G. Bassi, Elizabeth C. Rohrs, Karl C. Fernandez, Marlena Ornowska, Michelle Nicholas, Jessica Wittmann, Matt Gani, Doug Evans, Steven C. Reynolds
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Rationale: In porcine healthy-lung and moderate acute respiratory distress syndrome (ARDS) models, groups that received phrenic nerve stimulation (PNS) with mechanical ventilation (MV) showed lower hippocampal apoptosis, and microglia and astrocyte p
Externí odkaz:
https://doaj.org/article/36268b7c30274af4aae44e1e63bbe3a0
Autor:
Thiago G. Bassi, Elizabeth C. Rohrs, Karl C. Fernandez, Marlena Ornowska, Michelle Nicholas, Matt Gani, Doug Evans, Steven C. Reynolds
Publikováno v:
European Journal of Medical Research, Vol 27, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/e2821ef646d2406c96be86a8c42fbe57
Autor:
Elizabeth C. Rohrs, Thiago G. Bassi, Michelle Nicholas, Jessica Wittmann, Marlena Ornowska, Karl C. Fernandez, Matt Gani, Steven C. Reynolds
Publikováno v:
Canadian Journal of Respiratory Therapy, Vol 59 (2023)
Introduction Mechanical ventilator breaths provided to deeply sedated patients have an abnormal volume distribution, encouraging alveolar collapse in dependent regions and promoting alveolar overdistention in non-dependent regions. Collapse and over
Externí odkaz:
https://doaj.org/article/1c6329da315349c8891d1051d53af5b9
Autor:
Thiago G. Bassi, Elizabeth C. Rohrs, Karl C. Fernandez, Marlena Ornowska, Michelle Nicholas, Matt Gani, Doug Evans, Steven C. Reynolds
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Mechanical ventilation is the cornerstone of the Intensive Care Unit. However, it has been associated with many negative consequences. Recently, ventilator-induced brain injury has been reported in rodents under injurious ventilation setting
Externí odkaz:
https://doaj.org/article/648a6a24c0d54728b8a0e4a0eca8ddcb
Negative-pressure-assisted ventilation lowers driving pressure and mechanical power in an ARDS model
Autor:
Elizabeth C. Rohrs, Thiago G. Bassi, Michelle Nicholas, Jessica Wittmann, Marlena Ornowska, Karl C. Fernandez, Matt Gani, Steven C. Reynolds
Publikováno v:
Journal of Applied Physiology. 133:1237-1249
Increased lung heterogeneity from regional alveolar collapse drives ventilator-induced lung injury in patients with acute respiratory distress syndrome (ARDS). New methods of preventing this injury require study. Our study objective was to determine
Autor:
Karl C. Fernandez, Elizabeth C. Rohrs, Thiago G. Bassi, Marlena Ornowska, Michelle Nicholas, Matt Gani, Steven C. Reynolds
Publikováno v:
Journal of Applied Physiology.
Introduction: Mechanical ventilation (MV) induced diaphragmatic atrophy can contribute to weaning difficulties. A temporary transvenous diaphragm neurostimulation (TTDN) device that elicits diaphragm contractions has previously been shown to mitigate
Background: We aimed to determine if a novel digital therapeutic intervention could reduce agitation and unscheduled medication use in an adult delirious acute care population. Methods: Delirious participants were randomly allocated (1:1) to receive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d7f8e13ed3c7cded7006d73fd585f4
https://doi.org/10.2139/ssrn.4357913
https://doi.org/10.2139/ssrn.4357913