Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michelle Nguyen-McCarty"'
Autor:
Michelle Nguyen-McCarty, Peter S Klein
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177054 (2017)
Hematopoietic stem cells (HSCs) are able to self-renew and to differentiate into all blood cells. HSCs reside in a low-perfusion niche and depend on local signals to survive and to maintain the capacity for self-renewal. HSCs removed from the niche a
Externí odkaz:
https://doaj.org/article/545c205b4cfc46419ea046a3ade4d125
Autor:
Heather Jewell, Akinola Olumide Emmanuel, Albert Ruzo, Boris Gorovits, Caspian Harding, Bindu Varghese, Yonatan Lipsitz, Vidur Patel, Justine Cunningham, Sundeep Chandra, Victoria Duback, Hemant Chavan, Joohwan Kim, Michelle Nguyen-McCarty, Shannon Joyce, Aaron E. Foster, Carmela Passaro, Sergey Lyubinetsky, Lauren Pepper, Jason Rodriguez, Trevor McGill, Kelan Hlavaty, Misha Shamashkin, Paige Baldwin, Terry J. Fry, Shirisha Amatya, Carl Co, Salvatore Iovino, Jagesh V Shah, Hanane Ennajdaoui, Jess Elman, Allyse Mazzarelli, Donna Dambach, Kutlu G. Elpek, Carrie Rocca, Vasily Vagin, James Kaczmarek, Pattie Cruite, Michael Laska
Publikováno v:
Blood. 138:2769-2769
Introduction: Ex vivo manufactured chimeric antigen receptor (CAR) T cell therapies are highly effective for treating B cell malignancies. However, the complexity, cost and time required to manufacture CAR T cells limits access. To overcome conventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46946ed5099ec17431d5555f68d3aae8
https://doi.org/10.1182/blood-2021-148709
https://doi.org/10.1182/blood-2021-148709
Autor:
I. Collie, James Robinson, Jon Read, Roland Bürli, Nicholas J. Brandon, Carly I. Dix, Bernard G. Van den Hoven, Leslie C. Conway, Elizabeth Flavell, Dean G. Brown, Gerard Donohoe, Juli Warwicker, Jayanta Mukherjee, Stephen J. Haggarty, Eileen McCall, Michelle Nguyen-McCarty, Christopher Lucaj, Stephen J. Moss, Andrew Madin, Karolina Peciak
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(15)
The TRAF2 and NCK interacting kinase (TNIK) has been proposed to play a role in cytoskeletal organization and synaptic plasticity and has been linked, among others, to neurological disorders. However, target validation efforts for TNIK have been hamp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac38084604a3e61bd771a7855e143d8
https://pubmed.ncbi.nlm.nih.gov/31153805
https://pubmed.ncbi.nlm.nih.gov/31153805
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 5, p e0177054 (2017)
PLoS ONE, Vol 12, Iss 5, p e0177054 (2017)
Hematopoietic stem cells (HSCs) are able to self-renew and to differentiate into all blood cells. HSCs reside in a low-perfusion niche and depend on local signals to survive and to maintain the capacity for self-renewal. HSCs removed from the niche a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce486a793997de25f55fd2822cba973
https://pubmed.ncbi.nlm.nih.gov/28486555
https://pubmed.ncbi.nlm.nih.gov/28486555
Autor:
Peter S. Klein, Gwenn Danet-Desnoyers, Jian Huang, Michelle Nguyen-McCarty, Elizabeth O. Hexner
Publikováno v:
Nature Medicine. 18:1778-1785
Hematopoietic stem cell (HSC) self-renewal and lineage commitment depend on complex interactions with the microenvironment, and the ability to maintain or expand HSCs for clinical applications or for basic research has been significantly limited beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df562b67944b00c713089184a0303254
https://doi.org/10.1038/nm.2984
https://doi.org/10.1038/nm.2984
Autor:
Arjun G. Yodh, M. Celeste Simon, Amar J. Majmundar, Meeri N. Kim, Michelle Nguyen-McCarty, Rickson C. Mesquita, Nicolas Skuli
Publikováno v:
Molecular and Cellular Biology. 32:36-49
Skeletal muscle stem/progenitor cells, which give rise to terminally differentiated muscle, represent potential therapies for skeletal muscle diseases. Delineating the factors regulating these precursors will facilitate their reliable application in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9dfef207a50c9dc8ee6329b0d3980f9
https://doi.org/10.1128/mcb.05857-11
https://doi.org/10.1128/mcb.05857-11
Autor:
Andrew G. Szent-Györgyi, Elizabeth O'Neall-Hennessey, Ludmila Reshetnikova, Howard Robinson, V. S. Senthil Kumar, Michelle Nguyen-McCarty, Carolyn Cohen, Jerry H. Brown
Publikováno v:
Proceedings of the National Academy of Sciences. 108:114-119
We have determined the 2.3-Å-resolution crystal structure of a myosin light chain domain, corresponding to one type found in sea scallop catch (“smooth”) muscle. This structure reveals hinges that may function in the “on” and “off” stat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7736dfbbb15a4ea6d0f8c22542c6cffd
https://doi.org/10.1073/pnas.1016288107
https://doi.org/10.1073/pnas.1016288107
Autor:
Arjun G. Yodh, Nicolas Skuli, M. Celeste Simon, Bo Li, David Lee, Michelle Nguyen-McCarty, Rickson C. Mesquita, Amar J. Majmundar, Meeri N. Kim
Publikováno v:
Development (Cambridge, England). 142(14)
Deeper insight into the molecular pathways that orchestrate skeletal myogenesis should enhance our understanding of, and ability to treat, human skeletal muscle disease. It is now widely appreciated that nutrients, such as molecular oxygen (O2), modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0235a675c72debb48479d07f00a09b79
https://pubmed.ncbi.nlm.nih.gov/26153230
https://pubmed.ncbi.nlm.nih.gov/26153230
Autor:
Julia Durzyńska, Elisabeth R. Barton, Michelle Nguyen-McCarty, Anastassios Philippou, Becky K. Brisson
IGF-I is a key regulator of muscle development and growth. The pre-pro-peptide produced by the Igf1gene undergoes several posttranslational processing steps to result in a secreted mature protein, which is thought to be the obligate ligand for the IG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86af6b167284e39d51bfdcd81c1fa52e
https://europepmc.org/articles/PMC3578996/
https://europepmc.org/articles/PMC3578996/
Autor:
David Lee, M. C. Simon, Rickson C. Mesquita, Arjun G. Yodh, Michelle Nguyen-McCarty, Amar J. Majmundar, Meeri N. Kim, Nicolas Skuli, Bo Li
Publikováno v:
Journal of Cell Science. 128:e1.1-e1.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee068e5476e3cf1c5a76b94e64d9bd9c
https://doi.org/10.1242/jcs.177576
https://doi.org/10.1242/jcs.177576