Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michelle Naessens"'
Autor:
David J. Whiteside, Negin Holland, Kamen A. Tsvetanov, Elijah Mak, Maura Malpetti, George Savulich, P. Simon Jones, Michelle Naessens, Matthew A. Rouse, Tim D. Fryer, Young T. Hong, Franklin I. Aigbirhio, Eoin Mulroy, Kailash P. Bhatia, Timothy Rittman, John T. O’Brien, James B. Rowe
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract There is extensive synaptic loss from frontotemporal lobar degeneration, in preclinical models and human in vivo and post mortem studies. Understanding the consequences of synaptic loss for network function is important to support translatio
Externí odkaz:
https://doaj.org/article/ab6733cf5df64638bd28121108e81c94
Autor:
Rebecca S. Williams, Natalie E. Adams, Laura E. Hughes, Matthew A. Rouse, Alexander G. Murley, Michelle Naessens, Duncan Street, Negin Holland, James B. Rowe
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Self-report scales are widely used in cognitive neuroscience and psychology. However, they rest on the central assumption that respondents engage meaningfully. We hypothesise that this assumption does not hold for many patients, especially t
Externí odkaz:
https://doaj.org/article/cb2dd1242c3f43fcb9bed820594f2ca8
Autor:
Alistair Perry, Laura E. Hughes, Natalie E. Adams, Michelle Naessens, Niels A. Kloosterman, Matthew A. Rouse, Alexander G. Murley, Duncan Street, P. Simon Jones, James B. Rowe
Publikováno v:
NeuroImage: Clinical, Vol 44, Iss , Pp 103671- (2024)
The consequences of frontotemporal lobar degeneration include changes in prefrontal cortical neurophysiology, with abnormalities of neural dynamics reported in the beta frequency range (14–30 Hz) that correlate with functional severity. We examined
Externí odkaz:
https://doaj.org/article/fb0bc11b9ec4436c85e0049fd7bb33ad
Autor:
Amirhossein Jafarian, Laura E Hughes, Natalie E Adams, Juliette H Lanskey, Michelle Naessens, Matthew A Rouse, Alexander G Murley, Karl J Friston, James B Rowe
Publikováno v:
NeuroImage, Vol 276, Iss , Pp 120193- (2023)
We present a hierarchical empirical Bayesian framework for testing hypotheses about neurotransmitters’ concertation as empirical prior for synaptic physiology using ultra-high field magnetic resonance spectroscopy (7T-MRS) and magnetoencephalograph
Externí odkaz:
https://doaj.org/article/3b2e34d1cffc4173b7f79bedb62b773e
Autor:
Alistair Perry, Laura E. Hughes, Natalie Adams, Michelle Naessens, Alexander G. Murley, Matthew A. Rouse, Duncan Street, P. Simon Jones, Thomas E. Cope, Ece Kocagoncu, James B. Rowe
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract There is a pressing need to accelerate therapeutic strategies against the syndromes caused by frontotemporal lobar degeneration, including symptomatic treatments. One approach is for experimental medicine, coupling neurophysiological studies
Externí odkaz:
https://doaj.org/article/1404c4740e9a446ba5dcb7174bcaf05f
Autor:
Maura Malpetti, P. Simon Jones, Thomas E. Cope, Negin Holland, Michelle Naessens, Matthew A. Rouse, Timothy Rittman, George Savulich, David J. Whiteside, Duncan Street, Tim D. Fryer, Young T. Hong, Selena Milicevic Sephton, Franklin I. Aigbirhio, John T. O′Brien, James B. Rowe
Publikováno v:
Annals of Neurology. 93:142-154
Autor:
Negin Holland, P. Simon Jones, George Savulich, Michelle Naessens, Maura Malpetti, David J. Whiteside, Duncan Street, Peter Swann, Young T. Hong, Tim D. Fryer, Timothy Rittman, Eoin Mulroy, Franklin I. Aigbirhio, Kailash P. Bhatia, John T. O'Brien, James B. Rowe
Publikováno v:
Movement Disorders.
Autor:
Maura Malpetti, P Simon Jones, Thomas E Cope, Negin Holland, Michelle Naessens, Matthew A Rouse, George Savulich, Tim D Fryer, Young T Hong, Selena Milicevic‐Sephton, Franklin I Aigbirhio, John T O'Brien, James B Rowe
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Maura Malpetti, P. Simon Jones, Thomas E. Cope, Negin Holland, Michelle Naessens, Matthew A. Rouse, George Savulich, Tim D. Fryer, Young T. Hong, Selena Milicevic Sephton, Franklin I. Aigbirhio, John T. O’Brien, James B. Rowe
Synaptic loss is an early feature of neurodegenerative disease models, and is often severe inpost mortemclinical studies, including frontotemporal dementia. Positron emission tomography (PET) imaging with radiotracers that bind to synaptic vesicle gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afbf4a4e9cd982cbd2f8ca6c36c6fde0
https://doi.org/10.1101/2022.01.30.22270123
https://doi.org/10.1101/2022.01.30.22270123
Autor:
Michelle Naessens, Thomas E Cope, Alexander G Murley, Maura Malpetti, Catarina Rua, Laura E Hughes, Alistair Perry, Rong Ye, Chris T Rodgers, P Simon Jones, James B Rowe
Publikováno v:
Alzheimer's & Dementia. 17