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pro vyhledávání: '"Michelle N Mary-Sinclair"'
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116998 (2015)
Neuroblastomas (NBL) and Ewing's sarcomas (EWS) together cause 18% of all pediatric cancer deaths. Though there is growing interest in targeting the dysregulated metabolism of cancer as a therapeutic strategy, this approach has not been fully examine
Externí odkaz:
https://doaj.org/article/92a191977c3341d8a901357ae07c429d
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 1, p e0116998 (2015)
PLoS ONE, Vol 10, Iss 1, p e0116998 (2015)
Neuroblastomas (NBL) and Ewing’s sarcomas (EWS) together cause 18% of all pediatric cancer deaths. Though there is growing interest in targeting the dysregulated metabolism of cancer as a therapeutic strategy, this approach has not been fully exami
Publikováno v:
Molecular Cancer Research. 13:B37-B37
Oncogenic Myc is known to alter cellular metabolism resulting in glutamine addiction, and the MYCN-amplified subclass of neuroblastoma is associated with extremely poor prognosis. Successful identification of therapeutic agents that are effective in