Výsledky vyhledávání - "Michelle N, Rheault"

Akademický článek

Sparsentan for Focal Segmental Glomerulosclerosis in the DUET Open-Label Extension: Long-term Efficacy and Safety

Autor: Kirk N. Campbell, Loreto Gesualdo, Edward Murphy, Michelle N. Rheault, Tarak Srivastava, Vladimir Tesar, Radko Komers, Howard Trachtman

Publikováno v: Kidney Medicine, Vol 6, Iss 6, Pp 100833- (2024)

Rationale & Objective: Sparsentan is a novel, non-immunosuppressive, single-molecule, dual endothelin angiotensin receptor antagonist (DEARA) examined in the ongoing phase 2 DUET trial for focal segmental glomerulosclerosis (FSGS). In the DUET 8-week

Externí odkaz: https://doaj.org/article/0ba95d86e588438faad9ebaf7857f509

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Akademický článek

IgA Nephropathy Patient Baseline Characteristics in the Sparsentan PROTECT Study

Autor: Jonathan Barratt, Brad Rovin, Muh Geot Wong, Charles E. Alpers, Stewart Bieler, Ping He, Jula Inrig, Radko Komers, Hiddo J.L. Heerspink, Alex Mercer, Irene L. Noronha, Jai Radhakrishnan, Michelle N. Rheault, William Rote, Howard Trachtman, Hernán Trimarchi, Vlado Perkovic

Publikováno v: Kidney International Reports, Vol 8, Iss 5, Pp 1043-1056 (2023)

Introduction: Sparsentan is a novel single-molecule dual endothelin angiotensin receptor antagonist with hemodynamic and anti-inflammatory properties and is not an immunosuppressant. The ongoing phase 3 PROTECT trial examines sparsentan in adults wit

Externí odkaz: https://doaj.org/article/25a866cd50534c7d82716666703db077

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Akademický článek

A randomized controlled trial of preemptive rituximab to prevent recurrent focal segmental glomerulosclerosis post-kidney transplant (PRI-VENT FSGS): protocol and study design

Publikováno v: Frontiers in Nephrology, Vol 3 (2023)

BackgroundFocal segmental glomerulosclerosis (FSGS) is a common cause of end-stage kidney disease requiring kidney transplantation and can recur in the allograft in 30-80% of recipients resulting in reduced graft survival. Plasmapheresis has shown ef

Externí odkaz: https://doaj.org/article/bacc39cbba8e4ab09a1ad3f137ad1b59

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Akademický článek

Clinical presentation and management of nephrotic syndrome in the first year of life: A report from the Pediatric Nephrology Research Consortium

Autor: Alexandru R. Constantinescu, Tej K. Mattoo, William E. Smoyer, Larry A. Greenbaum, Jianli Niu, Noel Howard, Melissa Muff-Luett, Elizabeth B. Benoit, Avram Traum, Ali A. Annaim, Scott E. Wenderfer, Emilee Plautz, Michelle N. Rheault, Robert L. Myette, Katherine E. Twombley, Yu Kamigaki, Belkis Wandique-Rapalo, Mohammad Kallash, Tetyana L. Vasylyeva

Publikováno v: Frontiers in Pediatrics, Vol 10 (2022)

Background and objectivesNephrotic syndrome (NS) in the first year of life is called congenital (CNS) if diagnosed between 0–3 months, or infantile (INS) if diagnosed between 3–12 months of age. The aim of this study was to determine if there wer

Externí odkaz: https://doaj.org/article/2c81f7d437a546a6b74c2da321434120

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Akademický článek

A dual efficacy-implementation trial of a novel mobile application for childhood nephrotic syndrome management: the UrApp for childhood nephrotic syndrome management pilot study protocol (UrApp pilot study)

Autor: Chia-shi Wang, Cam Escoffery, Rachel E. Patzer, Courtney McCracken, Diana Ross, Michelle N. Rheault, Amira Al-Uzri, Larry A. Greenbaum

Publikováno v: BMC Nephrology, Vol 21, Iss 1, Pp 1-9 (2020)

Abstract Background Idiopathic nephrotic syndrome has a relapsing-remitting course in the majority of pediatric patients, demanding vigilant monitoring and self-management. A novel, expert-designed, user-informed mobile application (app), UrApp©, wa

Externí odkaz: https://doaj.org/article/747b7514d65e4b938989f6570a8ebf77

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Akademický článek

Treatment Patterns Among Adults and Children With Membranous Nephropathy in the Cure Glomerulonephropathy Network (CureGN)

Publikováno v: Kidney International Reports, Vol 4, Iss 12, Pp 1725-1734 (2019)

Introduction: The 2012 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guidelines for Glomerulonephritis recommend that patients with membranous nephropathy (MN) at risk for progression receive immunosuppressive therapy (IST), usu

Externí odkaz: https://doaj.org/article/1255736fdabe40e6baaf52e887c5cba6

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Akademický článek

The Social Media Revolution in Nephrology Education

Autor: Gates B. Colbert, Joel Topf, Kenar D. Jhaveri, Tom Oates, Michelle N. Rheault, Silvi Shah, Swapnil Hiremath, Matthew A. Sparks

Publikováno v: Kidney International Reports, Vol 3, Iss 3, Pp 519-529 (2018)

The past decade has been marked by the increasing use of social media platforms, often on mobile devices. In the nephrology community, this has resulted in the organic and continued growth of individuals interested in using these platforms for educat

Externí odkaz: https://doaj.org/article/9925bf25a32c447d93642b8c5d23708b

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Akademický článek

Prevalence of Cardiovascular Disease Risk Factors in Childhood Glomerular Diseases

Autor: Isa F. Ashoor, Sarah A. Mansfield, Michelle M. O'Shaughnessy, Rulan S. Parekh, Jarcy Zee, Tetyana L. Vasylyeva, Amy J. Kogon, Christine B. Sethna, Dorey A. Glenn, Aftab S. Chishti, Donald J. Weaver, Margaret E. Helmuth, Hilda E. Fernandez, Michelle N. Rheault

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 14 (2019)

Background Cardiovascular disease is a major cause of morbidity and mortality in children with chronic kidney disease. We sought to determine the prevalence of cardiovascular risk factors in children with glomerular disease and to describe current pr

Externí odkaz: https://doaj.org/article/3f407ad16004479aab6afe10a0479237

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