Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Michelle Miron"'
Autor:
Stefan Siebert, Kristen M. Sweet, Christopher T. Ritchlin, Elizabeth C. Hsia, Alexa P. Kollmeier, Xie L. Xu, Loqmane Seridi, Qingxuan Song, Sheng Gao, Warner Chen, Michelle Miron
Publikováno v:
ACR Open Rheumatology, Vol 5, Iss 9, Pp 490-498 (2023)
Objective To evaluate gene expression in blood of patients with psoriatic arthritis (PsA) versus healthy controls and identify changes associated with guselkumab treatment. Methods Whole blood transcriptome profiling via paired‐end RNA sequencing w
Externí odkaz:
https://doaj.org/article/ee686f1b1c8d4522be8be3992db06eb5
Autor:
Michelle Miron, Wenzhao Meng, Aaron M. Rosenfeld, Shirit Dvorkin, Maya Meimei Li Poon, Nora Lam, Brahma V. Kumar, Yoram Louzoun, Eline T. Luning Prak, Donna L. Farber
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Background Immune-mediated protection is mediated by T cells expressing pathogen-specific T cell antigen receptors (TCR) that are maintained at diverse sites of infection as tissue-resident memory T cells (TRM) or that disseminate as circula
Externí odkaz:
https://doaj.org/article/c9735e3dd8794a808679dc6e6b7b0c8f
Autor:
Peter A. Szabo, Hanna Mendes Levitin, Michelle Miron, Mark E. Snyder, Takashi Senda, Jinzhou Yuan, Yim Ling Cheng, Erin C. Bush, Pranay Dogra, Puspa Thapa, Donna L. Farber, Peter A. Sims
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Immune cells are shaped by the tissue environment, yet the states of healthy human T cells are mainly studied in the blood. Here, the authors perform single cell RNA-seq of T cells from tissues and blood of healthy donors and show its utility as a re
Externí odkaz:
https://doaj.org/article/630f23689fa444fe9d811c61653d4606
Autor:
Brahma V. Kumar, Wenji Ma, Michelle Miron, Tomer Granot, Rebecca S. Guyer, Dustin J. Carpenter, Takashi Senda, Xiaoyun Sun, Siu-Hong Ho, Harvey Lerner, Amy L. Friedman, Yufeng Shen, Donna L. Farber
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2921-2934 (2017)
Tissue-resident memory T cells (TRMs) in mice mediate optimal protective immunity to infection and vaccination, while in humans, the existence and properties of TRMs remain unclear. Here, we use a unique human tissue resource to determine whether hum
Externí odkaz:
https://doaj.org/article/f3e9780754764601b97c47d562f49b9a
Autor:
Stefan Siebert, Kristen M. Sweet, Christopher T. Ritchlin, Elizabeth C. Hsia, Alexa P. Kollmeier, Ya-Wen Yang, Xie L. Xu, Qingxuan Song, Michelle Miron
Publikováno v:
Journal of the American Academy of Dermatology. 87:AB170
Autor:
Erin C. Bush, Michelle Miron, Peter A. Szabo, Donna L. Farber, Jinzhou Yuan, Hanna Mendes Levitin, Pranay Dogra, Peter A. Sims, Mark E. Snyder, Puspa Thapa, Takashi Senda, Yim Ling Cheng
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
Human T cells coordinate adaptive immunity in diverse anatomic compartments through production of cytokines and effector molecules, but it is unclear how tissue site influences T cell persistence and function. Here, we use single cell RNA-sequencing
Autor:
Takashi Senda, Puspa Thapa, Kazuhiro Furuhashi, Peter A. Szabo, Donna L. Farber, Tomer Granot, Mark E. Snyder, Pranay Dogra, Dustin J. Carpenter, Michelle Miron
Publikováno v:
Mucosal Immunology. 12:378-389
Defining adaptive immunity with the complex structures of the human gastrointestinal (GI) tract over life is essential for understanding immune responses to ingested antigens, commensal and pathogenic microorganisms, and dysfunctions in disease. We p
Autor:
Shirit Dvorkin, Maya Meimei Li Poon, Yoram Louzoun, Nora Lam, Brahma V Kumar, Eline T. Luning Prak, Donna L. Farber, Michelle Miron, Wenzhao Meng, Aaron M. Rosenfeld
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Genome Medicine
Genome Medicine
BackgroundImmune-mediated protection is mediated by T cells expressing pathogen-specific T cell antigen receptors (TCR) that are maintained at diverse sites of infection as tissue-resident memory T cells (TRM) or that disseminate as circulating effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c81d2eea554e3d5ca673edab42bae8
Autor:
Yufeng Shen, Uri Hershberg, Wenzhao Meng, Aaron M. Rosenfeld, Takashi Senda, Bochao Zhang, Dora Chen, Dustin J. Carpenter, Adeeb Rahman, Eline T. Luning Prak, Amy L. Friedman, Tomer Granot, Brahma V. Kumar, Michelle Miron, Harvey Lerner, Donna L. Farber
Publikováno v:
The Journal of Immunology. 201:2132-2140
Translating studies on T cell function and modulation from mouse models to humans requires extrapolating in vivo results on mouse T cell responses in lymphoid organs (spleen and lymph nodes [LN]) to human peripheral blood T cells. However, our unders
Autor:
Rebecca S. Guyer, Dustin Carpener, Takashi Senda, Yufeng Shen, Amy L. Friedman, Tomer Granot, Michelle Miron, Harvey Lerner, Brahma V. Kumar, Xiaoyun Sun, Donna L. Farber, Siu-hong Ho, Wenji Ma
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2921-2934 (2017)
Tissue-resident memory T cells (TRMs) in mice mediate optimal protective immunity to infection and vaccination, while in humans, the existence and properties of TRMs remain unclear. Here, we use a unique human tissue resource to determine whether hum