Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Michelle Manikkam"'
Autor:
Xu Wang, Rachel L. Edwards, Haley Ball, Claire Johnson, Amanda Haymond, Misgina Girma, Michelle Manikkam, Robert C. Brothers, Kyle T. McKay, Stacy D. Arnett, Damon M. Osbourn, Sophie Alvarez, Helena I. Boshoff, Marvin J. Meyers, Robin D. Couch, Audrey R. Odom John, Cynthia S. Dowd
Publikováno v:
Journal of Medicinal Chemistry. 61:8847-8858
Severe malaria due to Plasmodium falciparum remains a significant global health threat. DXR, the second enzyme in the MEP pathway, plays an important role to synthesize building blocks for isoprenoids. This enzyme is a promising drug target for malar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dab6bfdd47146ebb8455b713ccd99ac
https://doi.org/10.1021/acs.jmedchem.8b01026
https://doi.org/10.1021/acs.jmedchem.8b01026
Autor:
Sangmi, Oh, Yumi, Park, Curtis A, Engelhart, Joshua B, Wallach, Dirk, Schnappinger, Kriti, Arora, Michelle, Manikkam, Brian, Gac, Hongwu, Wang, Nicholas, Murgolo, David B, Olsen, Michael, Goodwin, Michelle, Sutphin, Danielle M, Weiner, Laura E, Via, Helena I M, Boshoff, Clifton E, Barry
Publikováno v:
Journal of Medicinal Chemistry
Magnesium plays an important role in infection with Mycobacterium tuberculosis ( Mtb) as a signal of the extracellular environment, as a cofactor for many enzymes, and as a structural element in important macromolecules. Raltegravir, an antiretrovira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97a745304ea6d9591c7e0c801f5f3d87
https://pubmed.ncbi.nlm.nih.gov/30350998
https://pubmed.ncbi.nlm.nih.gov/30350998