Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Michelle M. Troch"'
Autor:
Carolyn Paisie, Julie H. Ostrander, Shauna N. Vasilatos, Siya Lem, Craig Rowell, Victoria Scott, Gregory R. Bean, Vanessa Goldenberg, Patrick G. Pilie, Lee G. Wilke, Joseph C. Baker, Michelle M. Troch, Carola M. Zalles, Alejandro Torres-Hernandez, Tracey L. Grant, Nicholas C. D'Amato, Victoria L. Seewaldt, Gloria Broadwater, Sarah Rabiner, Catherine Ibarra-Drendall
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 17:1884-1890
Purpose: Currently, we lack biomarkers to predict whether high-risk women with mammary atypia will respond to tamoxifen chemoprevention. Experimental Design: Thirty-four women with cytologic mammary atypia from the Duke University High-Risk clinic we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260771dddc2c12f0d9fc9b75838a067f
https://doi.org/10.1158/1055-9965.epi-07-2696
https://doi.org/10.1158/1055-9965.epi-07-2696
Autor:
Victoria L. Seewaldt, Michelle L. Bowie, Jeffrey J. Delrow, Michelle M. Troch, Eric C. Dietze, Gregory R. Bean, Catherine Ibarra, G Pandiyan
Publikováno v:
Oncogene. 26:2017-2026
Interactions between extracellular matrix (ECM) and mammary epithelial cells are critical for mammary gland homeostasis and apoptotic signaling. Interferon regulatory factor-1 (IRF-1) is a transcriptional regulator that promotes apoptosis during mamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c9e8ac5c3f7a54f91f9f2e28987e78b
https://doi.org/10.1038/sj.onc.1210013
https://doi.org/10.1038/sj.onc.1210013
Autor:
Jeffery J. Delrow, Michelle L. Bowie, Eric C. Dietze, Victoria L. Seewaldt, Gregory R. Bean, Michelle M. Troch, Robin J. Marjoram
Publikováno v:
Oncogene. 23:8743-8755
Unlike estrogen receptor-positive (ER(+)) breast cancers, normal human mammary epithelial cells (HMECs) typically express low nuclear levels of ER (ER poor). We previously demonstrated that 1.0 microM tamoxifen (Tam) promotes apoptosis in acutely dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9adb8867326acc7b2ead6da21aeb3d8e
https://doi.org/10.1038/sj.onc.1208120
https://doi.org/10.1038/sj.onc.1208120
Autor:
Eric C. Dietze, Gregory R. Bean, Michelle M. Troch, Michelle L. Bowie, Victoria L. Seewaldt, Lisa D. Yee
Publikováno v:
Biochemical and Biophysical Research Communications. 302:841-848
The coactivators CBP and p300 are recruited by retinoic acid receptors (RARs) during retinoid mediated transcriptional regulation. To assess the role of CBP/p300 in all-trans-retinoic acid (ATRA)-mediated growth arrest in mammary epithelial cells, tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a156b9a3e6f4f923f890e977a17714e
https://doi.org/10.1016/s0006-291x(03)00266-3
https://doi.org/10.1016/s0006-291x(03)00266-3
Autor:
Abigail Hoffman, Lee G. Wilke, Michelle M. Troch, Lance A. Liotta, Siya Lem, Melanie Shivraj, Jamila Williams, Priya Mehta, Julia Wulfkuhle, Joseph C. Baker, Carola M. Zalles, Laurie W. Lee, Patrick G. Pilie, Gloria Broadwater, William T. Barry, Nora Tolbert, Catherine Ibarra-Drendall, Dihua Yu, Anne Ford, Nicole M. Kuderer, Victoria L. Seewaldt, Emanuel F. Petricoin
Normal mammary gland homeostasis requires the coordinated regulation of protein signaling networks. However, we have little prospective information on whether activation of protein signaling occurs in premalignant mammary epithelial cells, as represe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a832be61ca1526a9e755306b162ef7aa
https://europepmc.org/articles/PMC3638770/
https://europepmc.org/articles/PMC3638770/
Autor:
Gloria Broadwater, Siya Lem, Zuowei Su, Dihua Yu, Joseph Geradts, William T. Barry, Melanie Shivraj, Patrick G. Pilie, Victoria L. Seewaldt, Lance A. Liotta, Emanuel F. Petricoin, Carola M. Zalles, Jamila Williams, Lee G. Wilke, Catherine Ibarra-Drendall, Michelle M. Troch, Julia Wulfkuhle, Anne Ford, Priya Mehta, Joseph C. Baker, April Stouder
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 20(3)
Background: Obesity is a well-established risk factor for cancer, accounting for up to 20% of cancer deaths in women. Studies of women with breast cancer have shown obesity to be associated with an increased risk of dying from breast cancer and incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ef579a4ea6216d2161d227d345b5fc
https://pubmed.ncbi.nlm.nih.gov/21242333
https://pubmed.ncbi.nlm.nih.gov/21242333
Autor:
Lisa D. Yee, Vanessa Goldenberg, Paul K. Marcom, Carol J. Fabian, Victoria L. Seewaldt, Gloria Broadwater, Lee G. Wilke, Carolyn Paisie, Michelle M. Troch, Victoria Scott, Carola M. Zalles, Catherine Ibarra Drendall, Joseph C. Baker, Bruce F. Kimler, Gregory R. Bean
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 16(1)
Mutation of the breast cancer–associated gene 1 (BRCA1) plays an important role in familial breast cancer. Although hypermethylation of the BRCA1 promoter has been observed in sporadic breast cancer, its exact role in breast cancer initiation and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5a8dc22465f244679bdf3cef7610298
https://pubmed.ncbi.nlm.nih.gov/17220331
https://pubmed.ncbi.nlm.nih.gov/17220331
Autor:
Michelle L. Bowie, Kazunari K. Yokoyama, Michelle M. Troch, L. Elizabeth Caldwell, Victoria L. Seewaldt, Cassandra L. Neal, Robin J. Marjoram, Krzysztof Mrózek, Gregory R. Bean, Eric C. Dietze, Catherine Ibarra
Publikováno v:
Journal of cell science. 118(Pt 21)
Interactions between normal mammary epithelial cells and extracellular matrix (ECM) are important for mammary gland homeostasis. Loss of interactions between ECM and normal mammary epithelial cells are thought to be an early event in mammary carcinog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d63fdeb4ff0111dd0de1bf7d4ba451
https://pubmed.ncbi.nlm.nih.gov/16219677
https://pubmed.ncbi.nlm.nih.gov/16219677
Autor:
Michelle M. Troch, Brooke Ratliff-Daniel, Michelle L. Bowie, Lisa D. Yee, Gregory R. Bean, Carol J. Fabian, Carola M. Zalles, Victoria L. Seewaldt, Gloria Broadwater, Lee G. Wilke, Joseph C. Baker, Bruce F. Kimler, Victoria Scott, Paul K. Marcom, Jaimie Slade, Pearl Seo
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 14(4)
Methylation of the retinoic acid receptor-β2 (RARβ2) P2 promoter is hypothesized to be an important mechanism for loss of RARβ2 function during early mammary carcinogenesis. The frequency of RARβ2 P2 methylation was tested in (a) 16 early stage b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5fb5db4320ea435e2cd3dd69f84c350
https://pubmed.ncbi.nlm.nih.gov/15824145
https://pubmed.ncbi.nlm.nih.gov/15824145
Autor:
Gregory R. Bean, Michelle L. Bowie, Paul B. Rosenberg, Michelle M. Troch, Brooke Ratliff, Eric C. Dietze, Victoria L. Seewaldt, Joshua B Heffner
Publikováno v:
Oncogene. 23(21)
Normal human mammary epithelial cells (HMECs), unlike estrogen receptor-positive (ER+) breast cancers, typically express low nuclear levels of ER (ER-'poor'). We previously demonstrated that 1.0 microM tamoxifen (Tam) induced apoptosis in ER-'poor' H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10461ac45b0eb462a34fb7b986c4b027
https://pubmed.ncbi.nlm.nih.gov/14990993
https://pubmed.ncbi.nlm.nih.gov/14990993